Martine I. Abboud
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Molecular and cellular mechanisms of HIF prolyl hydroxylase inhibitors in clinical trials
TL Yeh, TM Leissing, MI Abboud, CC Thinnes, O Atasoylu, JP Holt-Martyn, ...
Chemical science 8 (11), 7651-7668, 2017
The road to avibactam: the first clinically useful non-β-lactam working somewhat like a β-lactam
DY Wang, MI Abboud, MS Markoulides, J Brem, CJ Schofield
Future medicinal chemistry 8 (10), 1063-1084, 2016
Interaction of avibactam with class B metallo-β-lactamases
MI Abboud, C Damblon, J Brem, N Smargiasso, P Mercuri, B Gilbert, ...
Antimicrobial agents and chemotherapy 60 (10), 5655-5662, 2016
Structural basis for oxygen degradation domain selectivity of the HIF prolyl hydroxylases
R Chowdhury, IKH Leung, YM Tian, MI Abboud, W Ge, C Domene, ...
Nature communications 7 (1), 1-10, 2016
NMR-filtered virtual screening leads to non-metal chelating metallo-β-lactamase inhibitors
GB Li, MI Abboud, J Brem, H Someya, CT Lohans, SY Yang, J Spencer, ...
Chemical science 8 (2), 928-937, 2017
Targeting protein–protein interactions in the HIF system
SE Wilkins, MI Abboud, RL Hancock, CJ Schofield
ChemMedChem 11 (8), 773, 2016
Carcinogenic and neurotoxic risks of acrylamide and heavy metals from potato and corn chips consumed by the Lebanese population
E Hariri, MI Abboud, S Demirdjian, S Korfali, M Mroueh, RI Taleb
Journal of Food Composition and Analysis 42, 91-97, 2015
Comparison of Verona integron-borne metallo-β-lactamase (VIM) variants reveals differences in stability and inhibition profiles
A Makena, A Dzgn, J Brem, MA McDonough, AM Rydzik, MI Abboud, ...
Antimicrobial agents and chemotherapy 60 (3), 1377-1384, 2015
Lack of activity of recombinant HIF prolyl hydroxylases (PHDs) on reported non-HIF substrates
ME Cockman, K Lippl, YM Tian, HB Pegg, WDF Jnr, MI Abboud, R Heilig, ...
Elife 8, e46490, 2019
Structural and stereoelectronic insights into oxygenase-catalyzed formation of ethylene from 2-oxoglutarate
Z Zhang, TJ Smart, H Choi, F Hardy, CT Lohans, MI Abboud, ...
Proceedings of the National Academy of Sciences 114 (18), 4667-4672, 2017
In silico fragment-based design identifies subfamily B1 metallo-β-lactamase inhibitors
R Cain, J Brem, D Zollman, MA McDonough, RM Johnson, J Spencer, ...
Journal of medicinal chemistry 61 (3), 1255-1260, 2018
Crystallographic analyses of isoquinoline complexes reveal a new mode of metallo-β-lactamase inhibition
GB Li, J Brem, R Lesniak, MI Abboud, CT Lohans, IJ Clifton, SY Yang, ...
Chemical communications 53 (43), 5806-5809, 2017
2-Oxoglutarate regulates binding of hydroxylated hypoxia-inducible factor to prolyl hydroxylase domain 2
MI Abboud, TE McAllister, IKH Leung, R Chowdhury, C Jorgensen, ...
Chemical Communications 54 (25), 3130-3133, 2018
19F‐NMR Reveals the Role of Mobile Loops in Product and Inhibitor Binding by the So Paulo Metallo‐β‐Lactamase
MI Abboud, P Hinchliffe, J Brem, R Macsics, I Pfeffer, A Makena, ...
Angewandte Chemie International Edition 56 (14), 3862-3866, 2017
Cyclobutanone mimics of intermediates in metallo‐β‐lactamase catalysis
MI Abboud, M Kosmopoulou, AP Krismanich, JW Johnson, P Hinchliffe, ...
Chemistry (Weinheim an der Bergstrasse, Germany) 24 (22), 5734, 2018
Carcinogenic and neurotoxic risks of acrylamide consumed through caffeinated beverages among the lebanese population
GEZ Naous, A Merhi, MI Abboud, M Mroueh, RI Taleb
Chemosphere 208, 352-357, 2018
Normal tissue radioprotection by amifostine via Warburg-type effects
MI Koukourakis, A Giatromanolaki, CE Zois, D Kalamida, S Pouliliou, ...
Scientific reports 6 (1), 1-14, 2016
The Jumonji-C oxygenase JMJD7 catalyzes (3 S)-lysyl hydroxylation of TRAFAC GTPases
S Markolovic, Q Zhuang, SE Wilkins, CD Eaton, MI Abboud, MJ Katz, ...
Nature chemical biology 14 (7), 688-695, 2018
The clinically used iron chelator deferasirox is an inhibitor of epigenetic JumonjiC domain-containing histone demethylases
M Roatsch, I Hoffmann, MI Abboud, RL Hancock, H Tarhonskaya, KF Hsu, ...
ACS chemical biology 14 (8), 1737-1750, 2019
Non-competitive cyclic peptides for targeting enzyme–substrate complexes
TE McAllister, TL Yeh, MI Abboud, IKH Leung, ES Hookway, ONF King, ...
Chemical Science 9 (20), 4569-4578, 2018
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