|Bioengineered 3D platform to explore cell–ECM interactions and drug resistance of epithelial ovarian cancer cells|
D Loessner, KS Stok, MP Lutolf, DW Hutmacher, JA Clements, SC Rizzi
Biomaterials 31 (32), 8494-8506, 2010
|Can tissue engineering concepts advance tumor biology research?|
DW Hutmacher, D Loessner, S Rizzi, DL Kaplan, DJ Mooney, ...
Trends in biotechnology 28 (3), 125-133, 2010
|Translating tissue engineering technology platforms into cancer research|
DW Hutmacher, RE Horch, D Loessner, S Rizzi, S Sieh, JC Reichert, ...
Journal of cellular and molecular medicine 13 (8a), 1417-1427, 2009
|Design and fabrication of tubular scaffolds via direct writing in a melt electrospinning mode|
TD Brown, A Slotosch, L Thibaudeau, A Taubenberger, D Loessner, ...
Biointerphases 7 (1), 13, 2012
|Discrepancies between metabolic activity and DNA content as tool to assess cell proliferation in cancer research|
V Quent, D Loessner, T Friis, JC Reichert, DW Hutmacher
Journal of cellular and molecular medicine 14 (4), 1003-1013, 2010
|Gelatine methacrylamide-based hydrogels: An alternative three-dimensional cancer cell culture system|
E Kaemmerer, FPW Melchels, BM Holzapfel, T Meckel, DW Hutmacher, ...
Acta biomaterialia 10 (6), 2551-2562, 2014
|Reactivation of embryonic nodal signaling is associated with tumor progression and promotes the growth of prostate cancer cells|
MG Lawrence, NV Margaryan, D Loessner, A Collins, KM Kerr, M Turner, ...
The Prostate 71 (11), 1198-1209, 2011
|Kallikrein-Related Peptidase 7 Promotes Multicellular Aggregation via the α5β1 Integrin Pathway and Paclitaxel Chemoresistance in Serous Epithelial Ovarian Carcinoma|
Y Dong, OL Tan, D Loessner, C Stephens, C Walpole, GM Boyle, ...
Cancer research 70 (7), 2624-2633, 2010
|Species-specific homing mechanisms of human prostate cancer metastasis in tissue engineered bone|
BM Holzapfel, F Wagner, D Loessner, NP Holzapfel, L Thibaudeau, ...
Biomaterials 35 (13), 4108-4115, 2014
|The reduced expression of the HADH2 protein causes X-linked mental retardation, choreoathetosis, and abnormal behavior|
C Lenski, RF Kooy, E Reyniers, D Loessner, RJA Wanders, ...
The American Journal of Human Genetics 80 (2), 372-377, 2007
|Secretome and degradome profiling shows that Kallikrein-related peptidases 4, 5, 6, and 7 induce TGFβ-1 signaling in ovarian cancer cells|
H Shahinian, D Loessner, ML Biniossek, JN Kizhakkedathu, JA Clements, ...
Molecular oncology 8 (1), 68-82, 2014
|Tissue engineered humanized bone supports human hematopoiesis in vivo|
BM Holzapfel, DW Hutmacher, B Nowlan, V Barbier, L Thibaudeau, ...
Biomaterials 61, 103-114, 2015
|Growth of confined cancer spheroids: a combined experimental and mathematical modelling approach|
D Loessner, JA Flegg, HM Byrne, JA Clements, DW Hutmacher
Integrative Biology 5 (3), 597-605, 2013
|The kallikrein-related peptidase family: Dysregulation and functions during cancer progression|
T Kryza, ML Silva, D Loessner, N Heuzé-Vourc'h, JA Clements
|A bioengineered 3D ovarian cancer model for the assessment of peptidase–mediated enhancement of spheroid growth and intraperitoneal spread|
D Loessner, SC Rizzi, KS Stok, T Fuehrmann, B Hollier, V Magdolen, ...
Biomaterials 34 (30), 7389-7400, 2013
|Engineered microenvironments provide new insights into ovarian and prostate cancer progression and drug responses|
D Loessner, BM Holzapfel, JA Clements
Advanced drug delivery reviews 79, 193-213, 2014
|Combined expression of KLK4, KLK5, KLK6, and KLK7 by ovarian cancer cells leads to decreased adhesion and paclitaxel-induced chemoresistance|
D Loessner, V Quent, J Kraemer, EC Weber, DW Hutmacher, V Magdolen, ...
Gynecologic oncology 127 (3), 569-578, 2012
|Integrin αvβ3 upregulates integrin‐linked kinase expression in human ovarian cancer cells via enhancement of ILK gene transcription|
D Lössner, C Abou‐Ajram, A Benge, M Aumercier, M Schmitt, U Reuning
Journal of cellular physiology 220 (2), 367-375, 2009
|Integrin αvβ3 mediates upregulation of epidermal growth-factor receptor expression and activity in human ovarian cancer cells|
D Lössner, C Abou-Ajram, A Benge, U Reuning
The international journal of biochemistry & cell biology 40 (12), 2746-2761, 2008
|Metastasis of ovarian cancer is mediated by kallikrein related peptidases|
Y Dong, D Loessner, H Irving-Rodgers, A Obermair, JL Nicklin, ...
Clinical & experimental metastasis 31 (1), 135-147, 2014