Leo J. Lee
Leo J. Lee
Senior Research Scientist, University of Toronto
Verified email at psi.toronto.edu - Homepage
TitleCited byYear
Deep surveying of alternative splicing complexity in the human transcriptome by high-throughput sequencing
Q Pan, O Shai, LJ Lee, BJ Frey, BJ Blencowe
Nature genetics 40 (12), 1413, 2008
27452008
The human splicing code reveals new insights into the genetic determinants of disease
HY Xiong, B Alipanahi, LJ Lee, H Bretschneider, D Merico, RKC Yuen, ...
Science 347 (6218), 1254806, 2015
6562015
The evolutionary landscape of alternative splicing in vertebrate species
NL Barbosa-Morais, M Irimia, Q Pan, HY Xiong, S Gueroussov, LJ Lee, ...
Science 338 (6114), 1587-1593, 2012
6342012
Deep learning of the tissue-regulated splicing code
MKK Leung, HY Xiong, LJ Lee, BJ Frey
Bioinformatics 30 (12), i121-i129, 2014
2742014
Current-generation high-throughput sequencing: deepening insights into mammalian transcriptomes
BJ Blencowe, S Ahmad, LJ Lee
Genes & development 23 (12), 1379-1386, 2009
1762009
Genome-wide analysis of alternative splicing in Caenorhabditis elegans
AK Ramani, JA Calarco, Q Pan, S Mavandadi, Y Wang, AC Nelson, ...
Genome research 21 (2), 342-348, 2011
1332011
Functional coordination of alternative splicing in the mammalian central nervous system
M Fagnani, Y Barash, JY Ip, C Misquitta, Q Pan, AL Saltzman, O Shai, ...
Genome biology 8 (6), R108, 2007
1022007
Immunity through swarms: Agent-based simulations of the human immune system
C Jacob, J Litorco, L Lee
International Conference on Artificial Immune Systems, 400-412, 2004
632004
Mutations in STAMBP, encoding a deubiquitinating enzyme, cause microcephaly–capillary malformation syndrome
LM McDonell, GM Mirzaa, D Alcantara, J Schwartzentruber, MT Carter, ...
Nature genetics 45 (5), 556, 2013
622013
Adaptive Kalman filtering and smoothing for tracking vocal tract resonances using a continuous-valued hidden dynamic model
L Deng, LJ Lee, H Attias, A Acero
IEEE Transactions on Audio, Speech, and Language Processing 15 (1), 13-23, 2006
512006
A structured speech model with continuous hidden dynamics and prediction-residual training for tracking vocal tract resonances
L Deng, LJ Lee, H Attias, A Acero
2004 IEEE International Conference on Acoustics, Speech, and Signal …, 2004
422004
AVISPA: a web tool for the prediction and analysis of alternative splicing
Y Barash, J Vaquero-Garcia, J González-Vallinas, HY Xiong, W Gao, ...
Genome biology 14 (10), R114, 2013
322013
Challenges in estimating percent inclusion of alternatively spliced junctions from RNA-seq data
B Kakaradov, HY Xiong, LJ Lee, N Jojic, BJ Frey
BMC bioinformatics 13 (6), S11, 2012
292012
A functional articulatory dynamic model for speech production
LJ Lee, P Fieguth, L Deng
2001 IEEE International Conference on Acoustics, Speech, and Signal …, 2001
292001
A probabilistic living cell segmentation model
NN Kachouie, LJ Lee, P Fieguth
IEEE International Conference on Image Processing 2005 1, I-1137, 2005
242005
Method of speech recognition using variational inference with switching state space models
H Attias, LJ Lee, L Deng
US Patent 6,931,374, 2005
232005
Variational inference and learning for segmental switching state space models of hidden speech dynamics
LJ Lee, H Attias, L Deng
2003 IEEE International Conference on Acoustics, Speech, and Signal …, 2003
212003
Generating and designing DNA with deep generative models
N Killoran, LJ Lee, A Delong, D Duvenaud, BJ Frey
arXiv preprint arXiv:1712.06148, 2017
182017
Systems and methods for classifying, prioritizing and interpreting genetic variants and therapies using a deep neural network
B Frey, MKK Leung, AT Delong, HY Xiong, B Alipanahi, LJ Lee, ...
US Patent App. 14/739,432, 2016
172016
Variational inference and learning for segmental switching state space models of hidden speech dynamics
H Attias, L Deng, LJ Lee
US Patent 7,454,336, 2008
172008
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Articles 1–20