| Deep surveying of alternative splicing complexity in the human transcriptome by high-throughput sequencing Q Pan, O Shai, LJ Lee, BJ Frey, BJ Blencowe Nature genetics 40 (12), 1413, 2008 | 2919 | 2008 |
| The human splicing code reveals new insights into the genetic determinants of disease HY Xiong, B Alipanahi, LJ Lee, H Bretschneider, D Merico, RKC Yuen, ... Science 347 (6218), 1254806, 2015 | 746 | 2015 |
| The evolutionary landscape of alternative splicing in vertebrate species NL Barbosa-Morais, M Irimia, Q Pan, HY Xiong, S Gueroussov, LJ Lee, ... Science 338 (6114), 1587-1593, 2012 | 688 | 2012 |
| Deep learning of the tissue-regulated splicing code MKK Leung, HY Xiong, LJ Lee, BJ Frey Bioinformatics 30 (12), i121-i129, 2014 | 313 | 2014 |
| Current-generation high-throughput sequencing: deepening insights into mammalian transcriptomes BJ Blencowe, S Ahmad, LJ Lee Genes & development 23 (12), 1379-1386, 2009 | 184 | 2009 |
| Genome-wide analysis of alternative splicing in Caenorhabditis elegans AK Ramani, JA Calarco, Q Pan, S Mavandadi, Y Wang, AC Nelson, ... Genome research 21 (2), 342-348, 2011 | 139 | 2011 |
| Functional coordination of alternative splicing in the mammalian central nervous system M Fagnani, Y Barash, JY Ip, C Misquitta, Q Pan, AL Saltzman, O Shai, ... Genome biology 8 (6), R108, 2007 | 107 | 2007 |
| Mutations in STAMBP, encoding a deubiquitinating enzyme, cause microcephaly–capillary malformation syndrome LM McDonell, GM Mirzaa, D Alcantara, J Schwartzentruber, MT Carter, ... Nature genetics 45 (5), 556, 2013 | 70 | 2013 |
| Immunity through swarms: Agent-based simulations of the human immune system C Jacob, J Litorco, L Lee International Conference on Artificial Immune Systems, 400-412, 2004 | 64 | 2004 |
| Adaptive Kalman filtering and smoothing for tracking vocal tract resonances using a continuous-valued hidden dynamic model L Deng, LJ Lee, H Attias, A Acero IEEE transactions on audio, speech, and language processing 15 (1), 13-23, 2006 | 52 | 2006 |
| A structured speech model with continuous hidden dynamics and prediction-residual training for tracking vocal tract resonances L Deng, LJ Lee, H Attias, A Acero 2004 IEEE International Conference on Acoustics, Speech, and Signal …, 2004 | 42 | 2004 |
| AVISPA: a web tool for the prediction and analysis of alternative splicing Y Barash, J Vaquero-Garcia, J González-Vallinas, HY Xiong, W Gao, ... Genome biology 14 (10), R114, 2013 | 35 | 2013 |
| Challenges in estimating percent inclusion of alternatively spliced junctions from RNA-seq data B Kakaradov, HY Xiong, LJ Lee, N Jojic, BJ Frey BMC bioinformatics 13 (S6), S11, 2012 | 30 | 2012 |
| A functional articulatory dynamic model for speech production LJ Lee, P Fieguth, L Deng 2001 IEEE International Conference on Acoustics, Speech, and Signal …, 2001 | 29 | 2001 |
| Generating and designing DNA with deep generative models N Killoran, LJ Lee, A Delong, D Duvenaud, BJ Frey arXiv preprint arXiv:1712.06148, 2017 | 23 | 2017 |
| A probabilistic living cell segmentation model NN Kachouie, LJ Lee, P Fieguth IEEE International Conference on Image Processing 2005 1, I-1137, 2005 | 23 | 2005 |
| Method of speech recognition using variational inference with switching state space models H Attias, LJ Lee, L Deng US Patent 6,931,374, 2005 | 23 | 2005 |
| Systems and methods for classifying, prioritizing and interpreting genetic variants and therapies using a deep neural network B Frey, MKK Leung, AT Delong, HY Xiong, B Alipanahi, LJ Lee, ... US Patent 10,185,803, 2019 | 21 | 2019 |
| Variational inference and learning for segmental switching state space models of hidden speech dynamics LJ Lee, H Attias, L Deng 2003 IEEE International Conference on Acoustics, Speech, and Signal …, 2003 | 21 | 2003 |
| RED-ML: a novel, effective RNA editing detection method based on machine learning H Xiong, D Liu, Q Li, M Lei, L Xu, L Wu, Z Wang, S Ren, W Li, M Xia, L Lu, ... Gigascience 6 (5), gix012, 2017 | 19 | 2017 |
Brendan FreyFounder & CEO, Deep Genomics; Co-Founder, Vector Institute; Professor, University of TorontoVerified email at psi.toronto.edu
