Philippe P. Roux
Philippe P. Roux
Professor of Pathology and Cell Biology, IRIC, University of Montreal
Verified email at umontreal.ca - Homepage
TitleCited byYear
ERK and p38 MAPK-activated protein kinases: a family of protein kinases with diverse biological functions
PP Roux, J Blenis
Microbiol. Mol. Biol. Rev. 68 (2), 320-344, 2004
24492004
Activation and function of the MAPKs and their substrates, the MAPK-activated protein kinases
M Cargnello, PP Roux
Microbiol. Mol. Biol. Rev. 75 (1), 50-83, 2011
15682011
Tuberous sclerosis complex gene products, Tuberin and Hamartin, control mTOR signaling by acting as a GTPase-activating protein complex toward Rheb
AR Tee, BD Manning, PP Roux, LC Cantley, J Blenis
Current biology 13 (15), 1259-1268, 2003
10992003
Tumor-promoting phorbol esters and activated Ras inactivate the tuberous sclerosis tumor suppressor complex via p90 ribosomal S6 kinase
PP Roux, BA Ballif, R Anjum, SP Gygi, J Blenis
Proceedings of the National Academy of Sciences 101 (37), 13489-13494, 2004
7522004
Neurotrophin signaling through the p75 neurotrophin receptor
PP Roux, PA Barker
Progress in neurobiology 67 (3), 203-233, 2002
7202002
Rapamycin differentially inhibits S6Ks and 4E-BP1 to mediate cell-type-specific repression of mRNA translation
AY Choo, SO Yoon, SG Kim, PP Roux, J Blenis
Proceedings of the National Academy of Sciences 105 (45), 17414-17419, 2008
6982008
RAS/ERK signaling promotes site-specific ribosomal protein S6 phosphorylation via RSK and stimulates cap-dependent translation
PP Roux, D Shahbazian, H Vu, MK Holz, MS Cohen, J Taunton, ...
Journal of Biological Chemistry 282 (19), 14056-14064, 2007
5812007
The mTOR/PI3K and MAPK pathways converge on eIF4B to control its phosphorylation and activity
D Shahbazian, PP Roux, V Mieulet, MS Cohen, B Raught, J Taunton, ...
The EMBO journal 25 (12), 2781-2791, 2006
4622006
mTORC1-activated S6K1 phosphorylates Rictor on threonine 1135 and regulates mTORC2 signaling
LA Julien, A Carriere, J Moreau, PP Roux
Molecular and cellular biology 30 (4), 908-921, 2010
3652010
NRAGE, a novel MAGE protein, interacts with the p75 neurotrophin receptor and facilitates nerve growth factor–dependent apoptosis
AH Salehi, PP Roux, CJ Kubu, C Zeindler, A Bhakar, LL Tannis, JM Verdi, ...
Neuron 27 (2), 279-288, 2000
3322000
Oncogenic MAPK signaling stimulates mTORC1 activity by promoting RSK-mediated raptor phosphorylation
A Carrière, M Cargnello, LA Julien, H Gao, É Bonneil, P Thibault, ...
Current biology 18 (17), 1269-1277, 2008
2952008
Regulation and function of the RSK family of protein kinases
Y Romeo, X Zhang, PP Roux
Biochemical Journal 441 (2), 553-569, 2012
2572012
mTORC2 can associate with ribosomes to promote cotranslational phosphorylation and stability of nascent Akt polypeptide
WJ Oh, C Wu, SJ Kim, V Facchinetti, LA Julien, M Finlan, PP Roux, B Su, ...
The EMBO journal 29 (23), 3939-3951, 2010
2562010
p75 neurotrophin receptor expression is induced in apoptotic neurons after seizure
PP Roux, MA Colicos, PA Barker, TE Kennedy
Journal of neuroscience 19 (16), 6887-6896, 1999
2391999
Quantitative phosphorylation profiling of the ERK/p90 ribosomal S6 kinase-signaling cassette and its targets, the tuberous sclerosis tumor suppressors
BA Ballif, PP Roux, SA Gerber, JP MacKeigan, J Blenis, SP Gygi
Proceedings of the National Academy of Sciences 102 (3), 667-672, 2005
2342005
A comprehensive map of the mTOR signaling network
E Caron, S Ghosh, Y Matsuoka, D Ashton‐Beaucage, M Therrien, ...
Molecular systems biology 6 (1), 2010
2242010
ERK1/2 phosphorylate Raptor to promote Ras-dependent activation of mTOR complex 1 (mTORC1)
A Carriere, Y Romeo, HA Acosta-Jaquez, J Moreau, E Bonneil, P Thibault, ...
Journal of Biological Chemistry 286 (1), 567-577, 2011
2032011
Phosphorylation of p90 ribosomal S6 kinase (RSK) regulates extracellular signal-regulated kinase docking and RSK activity
PP Roux, SA Richards, J Blenis
Molecular and cellular biology 23 (14), 4796-4804, 2003
2002003
Transmembrane receptor DCC associates with protein synthesis machinery and regulates translation
J Tcherkezian, PA Brittis, F Thomas, PP Roux, JG Flanagan
Cell 141 (4), 632-644, 2010
1952010
The RSK factors of activating the Ras/MAPK signaling cascade
A Carriere, H Ray, J Blenis, PP Roux
Front Biosci 13 (10), 4258-4275, 2008
1792008
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Articles 1–20