Intratumor heterogeneity and branched evolution revealed by multiregion sequencing M Gerlinger, AJ Rowan, S Horswell, J Larkin, D Endesfelder, E Gronroos, ... N Engl j Med 366, 883-892, 2012 | 6513 | 2012 |
The MicroArray Quality Control (MAQC) project shows inter-and intraplatform reproducibility of gene expression measurements L Shi, LH Reid, WD Jones, R Shippy, JA Warrington, SC Baker, PJ Collins, ... Nature biotechnology 24 (9), 1151, 2006 | 2210 | 2006 |
An online survival analysis tool to rapidly assess the effect of 22,277 genes on breast cancer prognosis using microarray data of 1,809 patients B Györffy, A Lanczky, AC Eklund, C Denkert, J Budczies, Q Li, Z Szallasi Breast cancer research and treatment 123 (3), 725-731, 2010 | 1908 | 2010 |
Efficacy of neoadjuvant Cisplatin in triple-negative breast cancer DP Silver, AL Richardson, AC Eklund, ZC Wang, Z Szallasi, Q Li, N Juul, ... Journal of clinical oncology 28 (7), 1145, 2010 | 1021 | 2010 |
A signature of chromosomal instability inferred from gene expression profiles predicts clinical outcome in multiple human cancers SL Carter, AC Eklund, IS Kohane, LN Harris, Z Szallasi Nature genetics 38 (9), 1043-1048, 2006 | 944 | 2006 |
Reliability and reproducibility issues in DNA microarray measurements S Draghici, P Khatri, AC Eklund, Z Szallasi TRENDS in Genetics 22 (2), 101-109, 2006 | 695 | 2006 |
PGC-1α, a potential therapeutic target for early intervention in Parkinson’s disease B Zheng, Z Liao, JJ Locascio, KA Lesniak, SS Roderick, ML Watt, ... Science translational medicine 2 (52), 52ra73-52ra73, 2010 | 627 | 2010 |
Molecular markers of early Parkinson's disease based on gene expression in blood CR Scherzer, AC Eklund, LJ Morse, Z Liao, JJ Locascio, D Fefer, ... Proceedings of the National Academy of Sciences 104 (3), 955-960, 2007 | 496 | 2007 |
MicroRNA profile analysis of human prostate cancers AW Tong, P Fulgham, C Jay, P Chen, I Khalil, S Liu, N Senzer, AC Eklund, ... Cancer gene therapy 16 (3), 206-216, 2009 | 322 | 2009 |
Sequenza: allele-specific copy number and mutation profiles from tumor sequencing data F Favero, T Joshi, AM Marquard, NJ Birkbak, M Krzystanek, Q Li, ... Annals of Oncology 26 (1), 64-70, 2015 | 302 | 2015 |
Paradoxical relationship between chromosomal instability and survival outcome in cancer NJ Birkbak, AC Eklund, Q Li, SE McClelland, D Endesfelder, P Tan, ... Cancer research 71 (10), 3447-3452, 2011 | 273 | 2011 |
A large-scale analysis of tissue-specific pathology and gene expression of human disease genes and complexes K Lage, NT Hansen, EO Karlberg, AC Eklund, FS Roque, PK Donahoe, ... Proceedings of the National Academy of Sciences 105 (52), 20870-20875, 2008 | 269 | 2008 |
Telomeric allelic imbalance indicates defective DNA repair and sensitivity to DNA-damaging agents NJ Birkbak, ZC Wang, JY Kim, AC Eklund, Q Li, R Tian, C Bowman-Colin, ... Cancer discovery 2 (4), 366-375, 2012 | 262 | 2012 |
Chromosomal instability determines taxane response C Swanton, B Nicke, M Schuett, AC Eklund, C Ng, Q Li, T Hardcastle, ... Proceedings of the National Academy of Sciences 106 (21), 8671-8676, 2009 | 239 | 2009 |
GATA transcription factors directly regulate the Parkinson's disease-linked gene α-synuclein CR Scherzer, JA Grass, Z Liao, I Pepivani, B Zheng, AC Eklund, PA Ney, ... Proceedings of the National Academy of Sciences 105 (31), 10907-10912, 2008 | 238 | 2008 |
Jetset: selecting the optimal microarray probe set to represent a gene Q Li, NJ Birkbak, B Gyorffy, Z Szallasi, AC Eklund BMC bioinformatics 12 (1), 1-7, 2011 | 230 | 2011 |
Large-scale detection of antigen-specific T cells using peptide-MHC-I multimers labeled with DNA barcodes AK Bentzen, AM Marquard, R Lyngaa, SK Saini, S Ramskov, M Donia, ... Nature biotechnology 34 (10), 1037-1045, 2016 | 167 | 2016 |
Redefinition of Affymetrix probe sets by sequence overlap with cDNA microarray probes reduces cross-platform inconsistencies in cancer-associated gene expression measurements SL Carter, AC Eklund, BH Mecham, IS Kohane, Z Szallasi BMC bioinformatics 6 (1), 1-15, 2005 | 144 | 2005 |
Relationship of extreme chromosomal instability with long-term survival in a retrospective analysis of primary breast cancer R Roylance, D Endesfelder, P Gorman, RA Burrell, J Sander, I Tomlinson, ... Cancer Epidemiology and Prevention Biomarkers 20 (10), 2183-2194, 2011 | 127 | 2011 |
Tumor mutation burden forecasts outcome in ovarian cancer with BRCA1 or BRCA2 mutations NJ Birkbak, B Kochupurakkal, JMG Izarzugaza, AC Eklund, Y Li, J Liu, ... PloS one 8 (11), e80023, 2013 | 107 | 2013 |