Klaas Poelstra
Klaas Poelstra
Professor of Drug Targeting, University of Groningen
Verified email at rug.nl
Cited by
Cited by
Dephosphorylation of endotoxin by alkaline phosphatase in vivo.
K Poelstra, WW Bakker, PA Klok, JA Kamps, MJ Hardonk, DK Meijer
The American journal of pathology 151 (4), 1163, 1997
Cytokine regulation of pro-and anti-apoptotic genes in rat hepatocytes: NF-κB-regulated inhibitor of apoptosis protein 2 (cIAP2) prevents apoptosis
MH Schoemaker, JE Ros, M Homan, C Trautwein, P Liston, K Poelstra, ...
Journal of hepatology 36 (6), 742-750, 2002
A physiologic function for alkaline phosphatase: endotoxin detoxification.
K Poelstra, WW Bakker, PA Klok, MJ Hardonk, DK Meijer
Laboratory investigation; a journal of technical methods and pathology 76 (3 …, 1997
Removal of phosphate from lipid A as a strategy to detoxify lipopolysaccharide
H Bentala, WR Verweij, A Huizinga-Van der Vlag, ...
Shock 18 (6), 561-566, 2002
Albumin modified with mannose 6‐phosphate: A potential carrier for selective delivery of antifibrotic drugs to rat and human hepatic stellate cells
L Beljaars, G Molema, B Weert, H Bonnema, P Olinga, GM Groothuis, ...
Hepatology 29 (5), 1486-1493, 1999
Tauroursodeoxycholic acid protects rat hepatocytes from bile acid‐induced apoptosis via activation of survival pathways
MH Schoemaker, L Conde de la Rosa, M Buist‐Homan, TE Vrenken, ...
Hepatology 39 (6), 1563-1573, 2004
The effect of parenterally administered cyclodextrins on cholesterol levels in the rat
HW Frijlink, AC Eissens, NR Hefting, K Poelstra, CF Lerk, DKF Meijer
Pharmaceutical research 8 (1), 9-16, 1991
Successful targeting to rat hepatic stellate cells using albumin modified with cyclic peptides that recognize the collagen type VI receptor
L Beljaars, G Molema, D Schuppan, A Geerts, PJ De Bleser, B Weert, ...
Journal of Biological Chemistry 275 (17), 12743-12751, 2000
Resistance of rat hepatocytes against bile acid-induced apoptosis in cholestatic liver injury is due to nuclear factor-kappa B activation
MH Schoemaker, WM Gommans, LC de la Rosa, M Homan, P Klok, ...
Journal of hepatology 39 (2), 153-161, 2003
Role of alkaline phosphatase in colitis in man and rats
A Tuin, K Poelstra, A de Jager-Krikken, L Bok, W Raaben, MP Velders, ...
Gut 58 (3), 379-387, 2009
Reduction of advanced liver fibrosis by short‐term targeted delivery of an angiotensin receptor blocker to hepatic stellate cells in rats
M Moreno, T Gonzalo, RJ Kok, P Sancho‐Bru, M Van Beuge, J Swart, ...
Hepatology 51 (3), 942-952, 2010
Drug targeting to the diseased liver
K Poelstra, J Prakash, L Beljaars
Journal of Controlled Release 161 (2), 188-197, 2012
Targeting dexamethasone to Kupffer cells: effects on liver inflammation and fibrosis in rats
BN Melgert, P Olinga, JMS Van Der Laan, B Weert, J Cho, D Schuppan, ...
Hepatology 34 (4), 719-728, 2001
The preferential homing of a platelet derived growth factor receptor-recognizing macromolecule to fibroblast-like cells in fibrotic tissue
L Beljaars, B Weert, A Geerts, DKF Meijer, K Poelstra
Biochemical pharmacology 66 (7), 1307-1317, 2003
Targeting hepatic stellate cells for cell-specific treatment of liver fibrosis.
L Beljaars, DK Meijer, K Poelstra
Frontiers in bioscience: a journal and virtual library 7, e214-22, 2002
On the role and fate of LPS-dephosphorylating activity in the rat liver
A Tuin, A Huizinga-Van der Vlag, AMMA van Loenen-Weemaes, ...
American Journal of Physiology-Gastrointestinal and Liver Physiology 290 (2 …, 2006
Rat liver slices as a tool to study LPS-induced inflammatory response in the liver
P Olinga, MT Merema, MH De Jager, F Derks, BN Melgert, H Moshage, ...
Journal of hepatology 35 (2), 187-194, 2001
Local inhibition of liver fibrosis by specific delivery of a platelet-derived growth factor kinase inhibitor to hepatic stellate cells
T Gonzalo, L Beljaars, M Van De Bovenkamp, K Temming, ...
Journal of Pharmacology and Experimental Therapeutics 321 (3), 856-865, 2007
Intraglomerular platelet aggregation and experimental glomerulonephritis
K Poelstra, MJ Hardonk, J Koudstaal, WW Bakker
Kidney international 37 (6), 1500-1508, 1990
Characteristics of the hepatic stellate cell‐selective carrier mannose 6‐phosphate modified albumin (M6P28‐HSA)
L Beljaars, P Olinga, G Molema, P De Bleser, A Geerts, GMM Groothuis, ...
Liver 21 (5), 320-328, 2001
The system can't perform the operation now. Try again later.
Articles 1–20