| A conformational switch controls hepatitis delta virus ribozyme catalysis A Ke, K Zhou, F Ding, JHD Cate, JA Doudna Nature 429 (6988), 201-205, 2004 | 362 | 2004 |
| Cas5d protein processes pre-crRNA and assembles into a cascade-like interference complex in subtype IC/Dvulg CRISPR-Cas system KH Nam, C Haitjema, X Liu, F Ding, H Wang, MP DeLisa, A Ke Structure 20 (9), 1574-1584, 2012 | 258 | 2012 |
| Structures of CRISPR Cas3 offer mechanistic insights into Cascade-activated DNA unwinding and degradation Y Huo, KH Nam, F Ding, H Lee, L Wu, Y Xiao, MD Farchione Jr, S Zhou, ... Nature structural & molecular biology 21 (9), 771-777, 2014 | 240 | 2014 |
| Crystallization of RNA and RNA–protein complexes A Ke, JA Doudna Methods 34 (3), 408-414, 2004 | 199 | 2004 |
| Structure basis for directional R-loop formation and substrate handover mechanisms in type I CRISPR-Cas system Y Xiao, M Luo, RP Hayes, J Kim, S Ng, F Ding, M Liao, A Ke Cell 170 (1), 48-60. e11, 2017 | 192 | 2017 |
| Crystal structures of the SAM-III/SMK riboswitch reveal the SAM-dependent translation inhibition mechanism C Lu, AM Smith, RT Fuchs, F Ding, K Rajashankar, TM Henkin, A Ke Nature structural & molecular biology 15 (10), 1076-1083, 2008 | 188 | 2008 |
| Structural basis for promiscuous PAM recognition in type I–E Cascade from E. coli RP Hayes, Y Xiao, F Ding, PBG Van Erp, K Rajashankar, S Bailey, ... Nature 530 (7591), 499-503, 2016 | 185 | 2016 |
| The crystal structure of the signal recognition particle in complex with its receptor SF Ataide, N Schmitz, K Shen, A Ke, S Shan, JA Doudna, N Ban Science 331 (6019), 881-886, 2011 | 173 | 2011 |
| Introducing a spectrum of long-range genomic deletions in human embryonic stem cells using type I CRISPR-Cas AE Dolan, Z Hou, Y Xiao, MJ Gramelspacher, J Heo, SE Howden, ... Molecular cell 74 (5), 936-950. e5, 2019 | 157 | 2019 |
| How type II CRISPR–Cas establish immunity through Cas1–Cas2-mediated spacer integration Y Xiao, S Ng, KH Nam, A Ke Nature 550 (7674), 137-141, 2017 | 147 | 2017 |
| Envelope stress is a trigger of CRISPR RNA‐mediated DNA silencing in Escherichia coli R Perez‐Rodriguez, C Haitjema, Q Huang, KH Nam, S Bernardis, A Ke, ... Molecular microbiology 79 (3), 584-599, 2011 | 140 | 2011 |
| Mn2+-sensing mechanisms of yybP-ykoY orphan riboswitches IR Price, A Gaballa, F Ding, JD Helmann, A Ke Molecular cell 57 (6), 1110-1123, 2015 | 130 | 2015 |
| Double-stranded endonuclease activity in Bacillus halodurans clustered regularly interspaced short palindromic repeats (CRISPR)-associated Cas2 protein KH Nam, F Ding, C Haitjema, Q Huang, MP DeLisa, A Ke Journal of Biological Chemistry 287 (43), 35943-35952, 2012 | 127 | 2012 |
| Structure basis for RNA-guided DNA degradation by Cascade and Cas3 Y Xiao, M Luo, AE Dolan, M Liao, A Ke Science 361 (6397), eaat0839, 2018 | 125 | 2018 |
| Architecture of the yeast Rrp44–exosome complex suggests routes of RNA recruitment for 3′ end processing HW Wang, J Wang, F Ding, K Callahan, MA Bratkowski, JS Butler, ... Proceedings of the National Academy of Sciences 104 (43), 16844-16849, 2007 | 119 | 2007 |
| Massively parallel biophysical analysis of CRISPR-Cas complexes on next generation sequencing chips C Jung, JA Hawkins, SK Jones, Y Xiao, JR Rybarski, KE Dillard, ... Cell 170 (1), 35-47. e13, 2017 | 107 | 2017 |
| SAM recognition and conformational switching mechanism in the Bacillus subtilis yitJ S box/SAM-I riboswitch C Lu, F Ding, A Chowdhury, V Pradhan, J Tomsic, WM Holmes, ... Journal of molecular biology 404 (5), 803-818, 2010 | 104 | 2010 |
| Crystal structure of Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR)-associated Csn2 protein revealed Ca2+-dependent double-stranded DNA binding activity*♦ KH Nam, I Kurinov, A Ke Journal of Biological Chemistry 286 (35), 30759-30768, 2011 | 98 | 2011 |
| Assembly and translocation of a CRISPR-Cas primed acquisition complex KE Dillard, MW Brown, NV Johnson, Y Xiao, A Dolan, E Hernandez, ... Cell 175 (4), 934-946. e15, 2018 | 91 | 2018 |
| T box RNA decodes both the information content and geometry of tRNA to affect gene expression JC Grigg, Y Chen, FJ Grundy, TM Henkin, L Pollack, A Ke Proceedings of the National Academy of Sciences 110 (18), 7240-7245, 2013 | 84 | 2013 |
Jason GriggUniversity of British ColumbiaVerified email at mail.ubc.ca
