| Structure and mechanism of the glycerol-3-phosphate transporter from Escherichia coli Y Huang, MJ Lemieux, J Song, M Auer, DN Wang Science 301 (5633), 616-620, 2003 | 1212 | 2003 |
| Feline coronavirus drug inhibits the main protease of SARS-CoV-2 and blocks virus replication W Vuong, MB Khan, C Fischer, E Arutyunova, T Lamer, J Shields, ... Nature communications 11 (1), 4282, 2020 | 400 | 2020 |
| Crystallographic structure of human β-hexosaminidase A: interpretation of Tay-Sachs mutations and loss of GM2 ganglioside hydrolysis MJ Lemieux, BL Mark, MM Cherney, SG Withers, DJ Mahuran, ... Journal of molecular biology 359 (4), 913-929, 2006 | 222 | 2006 |
| Membrane protein structure, function, and dynamics: a perspective from experiments and theory Z Cournia, TW Allen, I Andricioaei, B Antonny, D Baum, G Brannigan, ... The Journal of membrane biology 248, 611-640, 2015 | 220 | 2015 |
| The crystal structure of the rhomboid peptidase from Haemophilus influenzae provides insight into intramembrane proteolysis MJ Lemieux, SJ Fischer, MM Cherney, KS Bateman, MNG James Proceedings of the National Academy of Sciences 104 (3), 750-754, 2007 | 178 | 2007 |
| Three‐dimensional crystallization of the Escherichia coli glycerol‐3‐phosphate transporter: A member of the major facilitator superfamily MJ Lemieux, J Song, MJ Kim, Y Huang, A Villa, M Auer, XD Li, DN Wang Protein science 12 (12), 2748-2756, 2003 | 140 | 2003 |
| Comprehensive in vitro characterization of PD-L1 small molecule inhibitors A Ganesan, M Ahmed, I Okoye, E Arutyunova, D Babu, WL Turnbull, ... Scientific reports 9 (1), 12392, 2019 | 115 | 2019 |
| Practical aspects of overexpressing bacterial secondary membrane transporters for structural studies DN Wang, M Safferling, MJ Lemieux, H Griffith, Y Chen, XD Li Biochimica et Biophysica Acta (BBA)-Biomembranes 1610 (1), 23-36, 2003 | 111 | 2003 |
| High-Yield Expression and Functional Analysis of Escherichia coli Glycerol-3-phosphate Transporter M Auer, MJ Kim, MJ Lemieux, A Villa, J Song, XD Li, DN Wang Biochemistry 40 (22), 6628-6635, 2001 | 109 | 2001 |
| Glycerol-3-phosphate transporter of Escherichia coli: structure, function and regulation MJ Lemieux, Y Huang, DN Wang Research in Microbiology 155 (8), 623-629, 2004 | 97 | 2004 |
| The structural basis of substrate translocation by the Escherichia coli glycerol-3-phosphate transporter: a member of the major facilitator superfamily MJ Lemieux, Y Huang, DN Wang Current opinion in structural biology 14 (4), 405-412, 2004 | 92 | 2004 |
| Proline residues in transmembrane segment IV are critical for activity, expression and targeting of the Na+/H+ exchanger isoform 1 ER Slepkov, S Chow, MJ Lemieux, L Fliegel Biochemical Journal 379 (1), 31-38, 2004 | 92 | 2004 |
| Peptidomimetic α-acyloxymethylketone warheads with six-membered lactam P1 glutamine mimic: SARS-CoV-2 3CL protease inhibition, coronavirus antiviral activity, and in vitro … B Bai, A Belovodskiy, M Hena, AS Kandadai, MA Joyce, HA Saffran, ... Journal of Medicinal Chemistry 65 (4), 2905-2925, 2021 | 80 | 2021 |
| Properties and biotechnological applications of acyl‐CoA: diacylglycerol acyltransferase and phospholipid: diacylglycerol acyltransferase from terrestrial plants and microalgae Y Xu, KMP Caldo, D Pal‐Nath, J Ozga, MJ Lemieux, RJ Weselake, ... Lipids 53 (7), 663-688, 2018 | 77 | 2018 |
| Allosteric regulation of rhomboid intramembrane proteolysis E Arutyunova, P Panwar, PM Skiba, N Gale, MW Mak, MJ Lemieux The EMBO journal 33 (17), 1869-1881, 2014 | 76 | 2014 |
| Importance of detergent and phospholipid in the crystallization of the human erythrocyte anion-exchanger membrane domain MJ Lemieux, RAF Reithmeier, DN Wang Journal of structural biology 137 (3), 322-332, 2002 | 76 | 2002 |
| Improved SARS-CoV-2 Mpro inhibitors based on feline antiviral drug GC376: Structural enhancements, increased solubility, and micellar studies W Vuong, C Fischer, MB Khan, MJ van Belkum, T Lamer, KD Willoughby, ... European journal of medicinal chemistry 222, 113584, 2021 | 72 | 2021 |
| Eukaryotic major facilitator superfamily transporter modeling based on the prokaryotic GlpT crystal structure MJ Lemieux Molecular membrane biology 24 (5-6), 333-341, 2007 | 60 | 2007 |
| Crystal structure and mechanism of GlpT, the glycerol-3-phosphate transporter from E. coli MJ Lemieux, Y Huang, DN Wang Journal of electron microscopy 54 (suppl_1), i43-i46, 2005 | 55 | 2005 |
| A genetically encoded fluorescent biosensor for extracellular l-lactate Y Nasu, C Murphy-Royal, Y Wen, JN Haidey, RS Molina, A Aggarwal, ... Nature communications 12 (1), 7058, 2021 | 50 | 2021 |
