| Presence of epidermal growth factor receptor gene T790M mutation as a minor clone in non–small cell lung cancer M Inukai, S Toyooka, S Ito, H Asano, S Ichihara, J Soh, H Suehisa, ... Cancer research 66 (16), 7854-7858, 2006 | 540 | 2006 |
| PIK3CA mutations and copy number gains in human lung cancers H Yamamoto, H Shigematsu, M Nomura, WW Lockwood, M Sato, ... Cancer research 68 (17), 6913-6921, 2008 | 530 | 2008 |
| Acquired resistance to EGFR inhibitors is associated with a manifestation of stem cell–like properties in cancer cells K Shien, S Toyooka, H Yamamoto, J Soh, M Jida, KL Thu, S Hashida, ... Cancer research 73 (10), 3051-3061, 2013 | 298 | 2013 |
| Genetic predictors of MEK dependence in non–small cell lung cancer CA Pratilas, AJ Hanrahan, E Halilovic, Y Persaud, J Soh, D Chitale, ... Cancer research 68 (22), 9375-9383, 2008 | 275 | 2008 |
| Oncogene mutations, copy number gains and mutant allele specific imbalance (MASI) frequently occur together in tumor cells J Soh, N Okumura, WW Lockwood, H Yamamoto, H Shigematsu, ... PloS one 4 (10), e7464, 2009 | 264 | 2009 |
| Alterations in genes of the EGFR signaling pathway and their relationship to EGFR tyrosine kinase inhibitor sensitivity in lung cancer cell lines J Gandhi, J Zhang, Y Xie, J Soh, H Shigematsu, W Zhang, H Yamamoto, ... PloS one 4 (2), e4576, 2009 | 233 | 2009 |
| Knockdown of oncogenic KRAS in non–small cell lung cancers suppresses tumor growth and sensitizes tumor cells to targeted therapy N Sunaga, DS Shames, L Girard, M Peyton, JE Larsen, H Imai, J Soh, ... Molecular cancer therapeutics 10 (2), 336-346, 2011 | 192 | 2011 |
| MET gene amplification or EGFR mutation activate MET in lung cancers untreated with EGFR tyrosine kinase inhibitors T Kubo, H Yamamoto, WW Lockwood, I Valencia, J Soh, M Peyton, M Jida, ... International journal of cancer 124 (8), 1778-1784, 2009 | 157 | 2009 |
| Frequent methylation and oncogenic role of microRNA-34b/c in small-cell lung cancer N Tanaka, S Toyooka, J Soh, T Kubo, H Yamamoto, Y Maki, T Muraoka, ... Lung cancer 76 (1), 32-38, 2012 | 147 | 2012 |
| The impact of epidermal growth factor receptor gene status on gefitinib‐treated Japanese patients with non‐small‐cell lung cancer S Ichihara, S Toyooka, Y Fujiwara, K Hotta, H Shigematsu, M Tokumo, ... International journal of cancer 120 (6), 1239-1247, 2007 | 147 | 2007 |
| Hereditary lung cancer syndrome targets never smokers with germline EGFR gene T790M mutations A Gazdar, L Robinson, D Oliver, C Xing, WD Travis, J Soh, S Toyooka, ... Journal of Thoracic Oncology 9 (4), 456-463, 2014 | 145 | 2014 |
| KRAS secondary mutations that confer acquired resistance to KRAS G12C inhibitors, sotorasib and adagrasib, and overcoming strategies: insights from in vitro experiments T Koga, K Suda, T Fujino, S Ohara, A Hamada, M Nishino, M Chiba, ... Journal of Thoracic Oncology 16 (8), 1321-1332, 2021 | 137 | 2021 |
| Epigenetic silencing of microRNA-34b/c plays an important role in the pathogenesis of malignant pleural mesothelioma T Kubo, S Toyooka, K Tsukuda, M Sakaguchi, T Fukazawa, J Soh, ... Clinical cancer research 17 (15), 4965-4974, 2011 | 132 | 2011 |
| Novel Germline Mutation in the Transmembrane Domain of HER2 in Familial Lung Adenocarcinomas H Yamamoto, K Higasa, M Sakaguchi, K Shien, J Soh, K Ichimura, ... Journal of the National Cancer Institute 106 (1), djt338, 2014 | 130 | 2014 |
| ERCC1 protein expression predicts the response of cisplatin-based neoadjuvant chemotherapy in non-small-cell lung cancer T Fujii, S Toyooka, K Ichimura, Y Fujiwara, K Hotta, J Soh, H Suehisa, ... Lung Cancer 59 (3), 377-384, 2008 | 127 | 2008 |
| Usefulness of EGFR mutation screening in pleural fluid to predict the clinical outcome of gefitinib treated patients with lung cancer J Soh, S Toyooka, K Aoe, H Asano, S Ichihara, H Katayama, A Hiraki, ... International journal of cancer 119 (10), 2353-2358, 2006 | 125 | 2006 |
| Prognostic impact of cancer stem cell-related markers in non-small cell lung cancer patients treated with induction chemoradiotherapy K Shien, S Toyooka, K Ichimura, J Soh, M Furukawa, Y Maki, T Muraoka, ... Lung cancer 77 (1), 162-167, 2012 | 121 | 2012 |
| Molecular oncology of lung cancer S Toyooka, T Mitsudomi, J Soh, K Aokage, M Yamane, T Oto, K Kiura, ... General thoracic and cardiovascular surgery 59, 527-537, 2011 | 107 | 2011 |
| The impact of sex and smoking status on the mutational spectrum of epidermal growth factor receptor gene in non–small cell lung cancer S Toyooka, K Matsuo, H Shigematsu, T Kosaka, M Tokumo, Y Yatabe, ... Clinical Cancer Research 13 (19), 5763-5768, 2007 | 105 | 2007 |
| CDKN2A/p16 inactivation mechanisms and their relationship to smoke exposure and molecular features in non–small-cell lung cancer KW Tam, W Zhang, J Soh, V Stastny, M Chen, H Sun, K Thu, JJ Rios, ... Journal of thoracic oncology 8 (11), 1378-1388, 2013 | 103 | 2013 |
Adi GazdarProfessor of Pathology, UT Southwestern Medical CenterVerified email at utsouthwestern.edu
