| Targeting the ubiquitin-proteasome pathway to overcome anti-cancer drug resistance S Narayanan, CY Cai, YG Assaraf, HQ Guo, Q Cui, L Wei, JJ Huang, ... Drug Resistance Updates 48, 100663, 2020 | 216 | 2020 |
| Multidrug resistance proteins (MRPs): Structure, function and the overcoming of cancer multidrug resistance JQ Wang, Y Yang, CY Cai, QX Teng, Q Cui, J Lin, YG Assaraf, ZS Chen Drug Resistance Updates 54, 100743, 2021 | 128 | 2021 |
| Dacomitinib antagonizes multidrug resistance (MDR) in cancer cells by inhibiting the efflux activity of ABCB1 and ABCG2 transporters YF Fan, W Zhang, L Zeng, ZN Lei, CY Cai, P Gupta, DH Yang, Q Cui, ... Cancer letters 421, 186-198, 2018 | 108 | 2018 |
| Selonsertib (GS-4997), an ASK1 inhibitor, antagonizes multidrug resistance in ABCB1-and ABCG2-overexpressing cancer cells N Ji, Y Yang, CY Cai, ZN Lei, JQ Wang, P Gupta, S Shukla, SV Ambudkar, ... Cancer letters 440, 82-93, 2019 | 99 | 2019 |
| Analogues of xanthones——Chalcones and bis-chalcones as α-glucosidase inhibitors and anti-diabetes candidates CY Cai, L Rao, Y Rao, JX Guo, ZZ Xiao, JY Cao, ZS Huang, B Wang European journal of medicinal chemistry 130, 51-59, 2017 | 97 | 2017 |
| Design and synthesis of novel xanthone-triazole derivatives as potential antidiabetic agents: α-Glucosidase inhibition and glucose uptake promotion GJ Ye, T Lan, ZX Huang, XN Cheng, CY Cai, SM Ding, ML Xie, B Wang European Journal of Medicinal Chemistry 177, 362-373, 2019 | 85 | 2019 |
| Tepotinib reverses ABCB1-mediated multidrug resistance in cancer cells ZX Wu, QX Teng, CY Cai, JQ Wang, ZN Lei, Y Yang, YF Fan, JY Zhang, ... Biochemical pharmacology 166, 120-127, 2019 | 57 | 2019 |
| Olmutinib (BI1482694/HM61713), a novel epidermal growth factor receptor tyrosine kinase inhibitor, reverses ABCG2-mediated multidrug resistance in cancer cells W Zhang, YF Fan, CY Cai, JQ Wang, QX Teng, ZN Lei, L Zeng, P Gupta, ... Frontiers in pharmacology 9, 1097, 2018 | 56 | 2018 |
| Tetrandrine interaction with ABCB1 reverses multidrug resistance in cancer cells through competition with anti-cancer drugs followed by downregulation of ABCB1 expression D Liao, W Zhang, P Gupta, ZN Lei, JQ Wang, CY Cai, AAD Vera, L Zhang, ... Molecules 24 (23), 4383, 2019 | 54 | 2019 |
| VS-4718 antagonizes multidrug resistance in ABCB1-and ABCG2-overexpressing cancer cells by inhibiting the efflux function of ABC transporters N Ji, Y Yang, CY Cai, ZN Lei, JQ Wang, P Gupta, QX Teng, ZS Chen, ... Frontiers in Pharmacology 9, 1236, 2018 | 52 | 2018 |
| Ulixertinib (BVD-523) antagonizes ABCB1-and ABCG2-mediated chemotherapeutic drug resistance N Ji, Y Yang, ZN Lei, CY Cai, JQ Wang, P Gupta, X Xian, DH Yang, ... Biochemical Pharmacology 158, 274-285, 2018 | 49 | 2018 |
| Hsa-miR-3178/RhoB/PI3K/Akt, a novel signaling pathway regulates ABC transporters to reverse gemcitabine resistance in pancreatic cancer J Gu, W Huang, X Wang, J Zhang, T Tao, Y Zheng, S Liu, J Yang, ... Molecular Cancer 21 (1), 112, 2022 | 41 | 2022 |
| Overexpression of ABCB1 transporter confers resistance to mTOR inhibitor WYE-354 in cancer cells J Wang, DH Yang, Y Yang, JQ Wang, CY Cai, ZN Lei, QX Teng, ZX Wu, ... International journal of molecular sciences 21 (4), 1387, 2020 | 35 | 2020 |
| Sitravatinib, a Tyrosine Kinase Inhibitor, Inhibits the Transport Function of ABCG2 and Restores Sensitivity to Chemotherapy-Resistant Cancer Cells in vitro Y Yang, N Ji, QX Teng, CY Cai, JQ Wang, ZX Wu, ZN Lei, S Lusvarghi, ... Frontiers in oncology 10, 700, 2020 | 34 | 2020 |
| Benzoyl indoles with metabolic stability as reversal agents for ABCG2-mediated multidrug resistance CY Cai, H Zhai, ZN Lei, CP Tan, BL Chen, ZY Du, JQ Wang, YK Zhang, ... European journal of medicinal chemistry 179, 849-862, 2019 | 32 | 2019 |
| Midostaurin Reverses ABCB1-Mediated Multidrug Resistance, an in vitro Study N Ji, Y Yang, CY Cai, JQ Wang, ZN Lei, ZX Wu, Q Cui, DH Yang, ZS Chen, ... Frontiers in oncology 9, 514, 2019 | 32 | 2019 |
| Cycloruthenated Self‐Assembly with Metabolic Inhibition to Efficiently Overcome Multidrug Resistance in Cancers J Li, L Zeng, Z Wang, H Chen, S Fang, J Wang, CY Cai, E Xing, X Liao, ... Advanced Materials 34 (1), 2100245, 2022 | 28 | 2022 |
| Biological evaluation of non-basic chalcone CYB-2 as a dual ABCG2/ABCB1 inhibitor CY Cai, W Zhang, JQ Wang, ZN Lei, YK Zhang, YJ Wang, P Gupta, ... Biochemical Pharmacology 175, 113848, 2020 | 27 | 2020 |
| Modulating the function of ABCB1: in vitro and in vivo characterization of sitravatinib, a tyrosine kinase inhibitor Y Yang, N Ji, CY Cai, JQ Wang, ZN Lei, QX Teng, ZX Wu, Q Cui, Y Pan, ... Cancer Communications 40 (7), 285-300, 2020 | 26 | 2020 |
| Glesatinib, a c-MET/SMO dual inhibitor, antagonizes P-glycoprotein mediated multidrug resistance in cancer cells Q Cui, CY Cai, HL Gao, L Ren, N Ji, P Gupta, Y Yang, S Shukla, ... Frontiers in Oncology 9, 313, 2019 | 26 | 2019 |
