| Odd-skipped related 1 is required for development of the metanephric kidney and regulates formation and differentiation of kidney precursor cells RG James, CN Kamei, Q Wang, R Jiang, TM Schultheiss Development 133 (15), 2995-3004, 2006 | 276 | 2006 |
| A disease-associated PTPN22 variant promotes systemic autoimmunity in murine models X Dai, RG James, T Habib, S Singh, S Jackson, S Khim, RT Moon, ... The Journal of clinical investigation 123 (5), 2024-2036, 2013 | 206 | 2013 |
| Wnt/β-catenin signaling and AXIN1 regulate apoptosis triggered by inhibition of the mutant kinase BRAFV600E in human melanoma TL Biechele, RM Kulikauskas, RA Toroni, OM Lucero, RD Swift, ... Science signaling 5 (206), ra3-ra3, 2012 | 204 | 2012 |
| A general molecular affinity strategy for global detection and proteomic analysis of lysine methylation KE Moore, SM Carlson, ND Camp, P Cheung, RG James, KF Chua, ... Molecular cell 50 (3), 444-456, 2013 | 193 | 2013 |
| Bmp signaling promotes intermediate mesoderm gene expression in a dose-dependent, cell-autonomous and translation-dependent manner RG James, TM Schultheiss Developmental biology 288 (1), 113-125, 2005 | 177 | 2005 |
| The forkhead genes, Foxc1 and Foxc2, regulate paraxial versus intermediate mesoderm cell fate B Wilm, RG James, TM Schultheiss, BLM Hogan Developmental biology 271 (1), 176-189, 2004 | 141 | 2004 |
| Wilms tumor gene on X chromosome (WTX) inhibits degradation of NRF2 protein through competitive binding to KEAP1 protein ND Camp, RG James, DW Dawson, F Yan, JM Davison, SA Houck, ... Journal of Biological Chemistry 287 (9), 6539-6550, 2012 | 136 | 2012 |
| The A946T variant of the RNA sensor IFIH1 mediates an interferon program that limits viral infection but increases the risk for autoimmunity JA Gorman, C Hundhausen, JS Errett, AE Stone, EJ Allenspach, Y Ge, ... Nature immunology 18 (7), 744-752, 2017 | 120 | 2017 |
| Engineering Protein-Secreting Plasma Cells by Homology-Directed Repair in Primary Human B Cells KL Hung, I Meitlis, M Hale, CY Chen, S Singh, SW Jackson, CH Miao, ... Molecular Therapy 26 (2), 456-67, 2018 | 110 | 2018 |
| WIKI4, a novel inhibitor of tankyrase and Wnt/ß-catenin signaling RG James, KC Davidson, KA Bosch, TL Biechele, NC Robin, RJ Taylor, ... PloS one 7 (12), e50457, 2012 | 107 | 2012 |
| Microfluidic device generating stable concentration gradients for long term cell culture: application to Wnt3a regulation of β-catenin signaling E Cimetta, C Cannizzaro, R James, T Biechele, RT Moon, N Elvassore, ... Lab on a Chip 10 (23), 3277-3283, 2010 | 105 | 2010 |
| Patterning of the avian intermediate mesoderm by lateral plate and axial tissues RG James, TM Schultheiss Developmental biology 253 (1), 109-124, 2003 | 102 | 2003 |
| Wnt/β‐catenin pathway regulates bone morphogenetic protein (BMP2)‐mediated differentiation of dental follicle cells KG Silvério, KC Davidson, RG James, AM Adams, BL Foster, FH Nociti Jr, ... Journal of periodontal research 47 (3), 309-319, 2012 | 97 | 2012 |
| β-catenin-independent Wnt pathways: signals, core proteins, and effectors RG James, WH Conrad, RT Moon Wnt signaling: Pathway methods and mammalian models, 131-144, 2008 | 86 | 2008 |
| Simvastatin promotes adult hippocampal neurogenesis by enhancing Wnt/β-catenin signaling NC Robin, Z Agoston, TL Biechele, RG James, JD Berndt, RT Moon Stem cell reports 2 (1), 9-17, 2014 | 79 | 2014 |
| Bruton’s tyrosine kinase revealed as a negative regulator of Wnt–β-catenin signaling RG James, TL Biechele, WH Conrad, ND Camp, DM Fass, MB Major, ... Science signaling 2 (72), ra25-ra25, 2009 | 70 | 2009 |
| Activated PIK3CD drives innate B cell expansion yet limits B cell–intrinsic immune responses MN Wray-Dutra, F Al Qureshah, G Metzler, M Oukka, RG James, ... Journal of Experimental Medicine 215 (10), 2485-2496, 2018 | 47 | 2018 |
| Recommendations for the collection and use of multiplexed functional data for clinical variant interpretation H Gelman, JN Dines, J Berg, AH Berger, S Brnich, FM Hisama, RG James, ... Genome Medicine 11, 1-11, 2019 | 44 | 2019 |
| A role for Vg1/Nodal signaling in specification of the intermediate mesoderm BM Fleming, R Yelin, RG James, TM Schultheiss Development 140 (8), 1819-1829, 2013 | 40 | 2013 |
| Multiplexed functional assessment of genetic variants in CARD11 I Meitlis, EJ Allenspach, BM Bauman, IQ Phan, G Dabbah, EG Schmitt, ... The American Journal of Human Genetics 107 (6), 1029-1043, 2020 | 39 | 2020 |
Alejandro Wolf-YadlinProfessor of Genome Sciences, University of WashingtonVerified email at uw.edu
