Cloning of a disintegrin metalloproteinase that processes precursor tumour-necrosis factor-α ML Moss, SLC Jin, ME Milla, W Burkhart, HL Carter, WJ Chen, WC Clay, ... Nature 385 (6618), 733-736, 1997 | 2111 | 1997 |
Regulation of tumour necrosis factor-α processing by a metalloproteinase inhibitor GM McGeehan, JD Becherer, RC Bast Jr, CM Boyer, B Champion, ... Nature 370 (6490), 558-561, 1994 | 724 | 1994 |
Evidence for a role of a tumor necrosis factor-α (TNF-α)-converting enzyme-like protease in shedding of TRANCE, a TNF family member involved in osteoclastogenesis and dendritic … L Lum, BR Wong, R Josien, JD Becherer, H Erdjument-Bromage, ... Journal of Biological Chemistry 274 (19), 13613-13618, 1999 | 590 | 1999 |
Intracellular maturation and localization of the tumour necrosis factor α convertase (TACE) J Schlöndorff, JD Becherer, CP Blobel Biochemical Journal 347 (1), 131-138, 2000 | 488 | 2000 |
Metalloprotease-disintegrin MDC9: intracellular maturation and catalytic activity M Roghani, JD Becherer, ML Moss, RE Atherton, H Erdjument-Bromage, ... Journal of Biological Chemistry 274 (6), 3531-3540, 1999 | 415 | 1999 |
Metalloproteinase inhibitors for the disintegrin-like metalloproteinases ADAM10 and ADAM17 that differentially block constitutive and phorbol ester-inducible shedding of cell … A Ludwig, C Hundhausen, MH Lambert, N Broadway, RC Andrews, ... Combinatorial chemistry & high throughput screening 8 (2), 161-171, 2005 | 414 | 2005 |
Involvement of the proteasome in the programmed cell death of NGF‐deprived sympathetic neurons. R Sadoul, PA Fernandez, AL Quiquerez, I Martinou, M Maki, M Schröter, ... The EMBO journal 15 (15), 3845-3852, 1996 | 331 | 1996 |
The Τumor Necrosis Factor-α Converting Enzyme (TACE): A Unique Metalloproteinase with Highly Defined Substrate Selectivity MJ Mohan, T Seaton, J Mitchell, A Howe, K Blackburn, W Burkhart, ... Biochemistry 41 (30), 9462-9469, 2002 | 301 | 2002 |
Granzyme A is an interleukin 1 beta-converting enzyme. M Irmler, S Hertig, HR MacDonald, R Sadoul, JD Becherer, A Proudfoot, ... The Journal of experimental medicine 181 (5), 1917-1922, 1995 | 286 | 1995 |
A potent and specific CD38 inhibitor ameliorates age-related metabolic dysfunction by reversing tissue NAD+ decline MG Tarragó, CCS Chini, KS Kanamori, GM Warner, A Caride, ... Cell metabolism 27 (5), 1081-1095. e10, 2018 | 276 | 2018 |
ADAM10 is a principal'sheddase'of the low-affinity immunoglobulin E receptor CD23 G Weskamp, JW Ford, J Sturgill, S Martin, AJP Docherty, S Swendeman, ... Nature immunology 7 (12), 1293-1298, 2006 | 272 | 2006 |
Altered tumor necrosis factor-α (TNF-α) processing in adipocytes and increased expression of transmembrane TNF-α in obesity H Xu, KT Uysal, JD Becherer, P Arner, GS Hotamisligil Diabetes 51 (6), 1876-1883, 2002 | 272 | 2002 |
Specific sequence elements are required for the expression of functional tumor necrosis factor-α-converting enzyme (TACE) ME Milla, MA Leesnitzer, ML Moss, WC Clay, HL Carter, AB Miller, JL Su, ... Journal of Biological Chemistry 274 (43), 30563-30570, 1999 | 227 | 1999 |
Evidence for a critical role of the tumor necrosis factor α convertase (TACE) in ectodomain shedding of the p75 neurotrophin receptor (p75NTR) G Weskamp, J Schlöndorff, L Lum, JD Becherer, TW Kim, P Saftig, ... Journal of Biological Chemistry 279 (6), 4241-4249, 2004 | 202 | 2004 |
The enzymatic activity of ADAM8 and ADAM9 is not regulated by TIMPs A Amour, CG Knight, WR English, A Webster, PM Slocombe, V Knäuper, ... FEBS letters 524 (1-3), 154-158, 2002 | 187 | 2002 |
Structural features and biochemical properties of TNF-α converting enzyme (TACE) ML Moss, SLC Jin, JD Becherer, DM Bickett, W Burkhart, WJ Chen, ... Journal of neuroimmunology 72 (2), 127-129, 1997 | 172 | 1997 |
Catalytic properties of ADAM19 V Chesneau, JD Becherer, Y Zheng, H Erdjument-Bromage, P Tempst, ... Journal of Biological Chemistry 278 (25), 22331-22340, 2003 | 156 | 2003 |
Biochemical properties and functions of membrane-anchored metalloprotease-disintegrin proteins (ADAMs) JD Becherer, CP Blobel Academic Press 54, 101-123, 2003 | 132 | 2003 |
Dissection of CR1, factor H, membrane cofactor protein, and factor B binding and functional sites in the third complement component. JD Lambris, Z Lao, TJ Oglesby, JP Atkinson, CE Hack, JD Becherer Journal of immunology (Baltimore, Md.: 1950) 156 (12), 4821-4832, 1996 | 126 | 1996 |
Discovery, synthesis, and biological evaluation of thiazoloquin (az) olin (on) es as potent CD38 inhibitors CD Haffner, JD Becherer, EE Boros, R Cadilla, T Carpenter, D Cowan, ... Journal of medicinal chemistry 58 (8), 3548-3571, 2015 | 121 | 2015 |