Sanjeev Gupta
Sanjeev Gupta
Discipline of Pathology, NUI Galway
Verified email at - Homepage
Cited by
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The eIF2α kinases: their structures and functions
N Donnelly, AM Gorman, S Gupta, A Samali
Cellular and Molecular Life Sciences 70 (19), 3493-3511, 2013
PERK is required at the ER-mitochondrial contact sites to convey apoptosis after ROS-based ER stress
T Verfaillie, N Rubio, AD Garg, G Bultynck, R Rizzuto, JP Decuypere, ...
Cell Death & Differentiation 19 (11), 1880-1891, 2012
Loss of Omi mitochondrial protease activity causes the neuromuscular disorder of mnd2 mutant mice
JM Jones, P Datta, SM Srinivasula, W Ji, S Gupta, ZJ Zhang, E Davies, ...
Nature 425 (6959), 721-727, 2003
Targeting the endoplasmic reticulum-stress response as an anticancer strategy
SJM Healy, AM Gorman, P Mousavi-Shafaei, S Gupta, A Samali
European journal of pharmacology 625 (1-3), 234-246, 2009
Unfolded proteins and endoplasmic reticulum stress in neurodegenerative disorders
KM Doyle, D Kennedy, AM Gorman, S Gupta, SJM Healy, A Samali
Journal of cellular and molecular medicine 15 (10), 2025-2039, 2011
Bcl-2 family on guard at the ER
E Szegezdi, DC MacDonald, T Ní Chonghaile, S Gupta, A Samali
American Journal of Physiology-Cell Physiology 296 (5), C941-C953, 2009
Methods for monitoring endoplasmic reticulum stress and the unfolded protein response
A Samali, U FitzGerald, S Deegan, S Gupta
International journal of cell biology 2010, 2010
Inhibitor of apoptosis proteins are substrates for the mitochondrial serine protease Omi/HtrA2
SM Srinivasula, S Gupta, P Datta, ZJ Zhang, R Hegde, NE Cheong, ...
Journal of Biological Chemistry 278 (34), 31469-31472, 2003
HSP72 protects cells from ER stress-induced apoptosis via enhancement of IRE1α-XBP1 signaling through a physical interaction
S Gupta, A Deepti, S Deegan, F Lisbona, C Hetz, A Samali
PLoS Biol 8 (7), e1000410, 2010
Regulation of HAX-1 anti-apoptotic protein by Omi/HtrA2 protease during cell death
L Cilenti, MM Soundarapandian, GA Kyriazis, V Stratico, S Singh, S Gupta, ...
Journal of Biological Chemistry 279 (48), 50295-50301, 2004
The mitochondrial death pathway: a promising therapeutic target in diseases
S Gupta, GEN Kass, E Szegezdi, B Joseph
Journal of cellular and molecular medicine 13 (6), 1004-1033, 2009
cIAP2 is a ubiquitin protein ligase for BCL10 and is dysregulated in mucosa-associated lymphoid tissue lymphomas
S Hu, MQ Du, SM Park, A Alcivar, L Qu, S Gupta, J Tang, M Baens, H Ye, ...
The Journal of clinical investigation 116 (1), 174-181, 2006
Direct transcriptional activation of human caspase-1 by tumor suppressor p53
S Gupta, V Radha, Y Furukawa, G Swarup
Journal of Biological Chemistry 276 (14), 10585-10588, 2001
The C-terminal tail of presenilin regulates Omi/HtrA2 protease activity
S Gupta, R Singh, P Datta, ZJ Zhang, C Orr, Z Lu, G DuBois, AS Zervos, ...
Journal of Biological Chemistry 279 (44), 45844-45854, 2004
Perk-dependent repression of miR-106b-25 cluster is required for ER stress-induced apoptosis
S Gupta, DE Read, A Deepti, K Cawley, A Gupta, D Oommen, T Verfaillie, ...
Cell death & disease 3 (6), e333-e333, 2012
Mechanisms of ER stress-mediated mitochondrial membrane permeabilization
S Gupta, L Cuffe, E Szegezdi, SE Logue, C Neary, S Healy, A Samali
International journal of cell biology 2010, 2010
Caspase-1 activator Ipaf is a p53-inducible gene involved in apoptosis
S Sadasivam, S Gupta, V Radha, K Batta, TK Kundu, G Swarup
Oncogene 24 (4), 627-636, 2005
A close connection between the PERK and IRE arms of the UPR and the transcriptional regulation of autophagy
S Deegan, I Koryga, SA Glynn, S Gupta, AM Gorman, A Samali
Biochemical and biophysical research communications 456 (1), 305-311, 2015
Assays for detecting the unfolded protein response
K Cawley, S Deegan, A Samali, S Gupta
Methods in enzymology 490, 31-51, 2011
A nuclear protein tyrosine phosphatase activates p53 and induces caspase‐1‐dependent apoptosis
S Gupta, V Radha, C Sudhakar, G Swarup
FEBS letters 532 (1-2), 61-66, 2002
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