| BBS6, BBS10, and BBS12 form a complex with CCT/TRiC family chaperonins and mediate BBSome assembly S Seo, LM Baye, NP Schulz, JS Beck, Q Zhang, DC Slusarski, ... Proceedings of the National Academy of Sciences 107 (4), 1488-1493, 2010 | 359 | 2010 |
| Requirement of Bardet-Biedl syndrome proteins for leptin receptor signaling S Seo, DF Guo, K Bugge, DA Morgan, K Rahmouni, VC Sheffield Human molecular genetics 18 (7), 1323-1331, 2009 | 344 | 2009 |
| Leptin resistance contributes to obesity and hypertension in mouse models of Bardet-Biedl syndrome K Rahmouni, MA Fath, S Seo, DR Thedens, CJ Berry, R Weiss, ... The Journal of clinical investigation 118 (4), 1458-1467, 2008 | 262 | 2008 |
| ARL13B, PDE6D, and CEP164 form a functional network for INPP5E ciliary targeting MC Humbert, K Weihbrecht, CC Searby, Y Li, RM Pope, VC Sheffield, ... Proceedings of the National Academy of Sciences 109 (48), 19691-19696, 2012 | 242 | 2012 |
| Neurogenin and NeuroD direct transcriptional targets and their regulatory enhancers S Seo, JW Lim, D Yellajoshyula, LW Chang, KL Kroll The EMBO journal 26 (24), 5093-5108, 2007 | 231 | 2007 |
| A novel protein LZTFL1 regulates ciliary trafficking of the BBSome and Smoothened S Seo, Q Zhang, K Bugge, DK Breslow, CC Searby, MV Nachury, ... PLoS genetics 7 (11), e1002358, 2011 | 229 | 2011 |
| The SWI/SNF chromatin remodeling protein Brg1 is required for vertebrate neurogenesis and mediates transactivation of Ngn and NeuroD S Seo, GA Richardson, KL Kroll Oxford University Press for The Company of Biologists Limited 132 (1), 105-115, 2005 | 229 | 2005 |
| Geminin regulates neuronal differentiation by antagonizing Brg1 activity S Seo, A Herr, JW Lim, GA Richardson, H Richardson, KL Kroll Genes & development 19 (14), 1723-1734, 2005 | 214 | 2005 |
| Intrinsic protein-protein interaction-mediated and chaperonin-assisted sequential assembly of stable bardet-biedl syndrome protein complex, the BBSome Q Zhang, D Yu, S Seo, EM Stone, VC Sheffield Journal of Biological Chemistry 287 (24), 20625-20635, 2012 | 179 | 2012 |
| BBS proteins interact genetically with the IFT pathway to influence SHH-related phenotypes Q Zhang, S Seo, K Bugge, EM Stone, VC Sheffield Human molecular genetics 21 (9), 1945-1953, 2012 | 170 | 2012 |
| Bardet-Biedl syndrome 3 (Bbs3) knockout mouse model reveals common BBS-associated phenotypes and Bbs3 unique phenotypes Q Zhang, D Nishimura, S Seo, T Vogel, DA Morgan, C Searby, K Bugge, ... Proceedings of the National Academy of Sciences 108 (51), 20678-20683, 2011 | 170 | 2011 |
| Accumulation of non-outer segment proteins in the outer segment underlies photoreceptor degeneration in Bardet–Biedl syndrome P Datta, C Allamargot, JS Hudson, EK Andersen, S Bhattarai, AV Drack, ... Proceedings of the National Academy of Sciences 112 (32), E4400-E4409, 2015 | 137 | 2015 |
| Abnormal development of NG2+PDGFR-α+ neural progenitor cells leads to neonatal hydrocephalus in a ciliopathy mouse model CS Carter, TW Vogel, Q Zhang, S Seo, RE Swiderski, TO Moninger, ... Nature medicine 18 (12), 1797-1804, 2012 | 131 | 2012 |
| Subretinal gene therapy of mice with Bardet-Biedl syndrome type 1 S Seo, RF Mullins, AV Dumitrescu, S Bhattarai, D Gratie, K Wang, ... Investigative ophthalmology & visual science 54 (9), 6118-6132, 2013 | 102 | 2013 |
| INPP5E interacts with AURKA, linking phosphoinositide signaling to primary cilium stability OV Plotnikova, S Seo, DL Cottle, S Conduit, S Hakim, JM Dyson, ... Journal of cell science 128 (2), 364-372, 2015 | 92 | 2015 |
| Geminin's double life: chromatin connections that regulate transcription at the transition from proliferation to differentiation S Seo, KL Kroll Cell Cycle 5 (4), 374-379, 2006 | 78 | 2006 |
| BBS mutations modify phenotypic expression of CEP290-related ciliopathies Y Zhang, S Seo, S Bhattarai, K Bugge, CC Searby, Q Zhang, AV Drack, ... Human molecular genetics 23 (1), 40-51, 2014 | 75 | 2014 |
| BBSome function is required for both the morphogenesis and maintenance of the photoreceptor outer segment Y Hsu, JE Garrison, G Kim, AR Schmitz, CC Searby, Q Zhang, P Datta, ... PLoS genetics 13 (10), e1007057, 2017 | 70 | 2017 |
| Spl and C/EBP-related factor regulate the transcription of human Cu/Zn SOD gene SJ Seo, HT Kim, G Cho, HM Rho, G Jung Gene 178 (1-2), 177-185, 1996 | 66 | 1996 |
| The centriolar satellite protein AZI1 interacts with BBS4 and regulates ciliary trafficking of the BBSome X Chamling, S Seo, CC Searby, GH Kim, DC Slusarski, VC Sheffield PLoS genetics 10 (2), e1004083, 2014 | 48 | 2014 |
Val C. Sheffield, M.D., Ph.D.Investigator, Howard Hughes Medical Institute, Professor of Pediatrics, University of IowaVerified email at uiowa.edu
