AraGEM, a genome-scale reconstruction of the primary metabolic network in Arabidopsis CG de Oliveira Dal'Molin, LE Quek, RW Palfreyman, SM Brumbley, ... Plant physiology 152 (2), 579-589, 2010 | 398 | 2010 |
Recon 2.2: from reconstruction to model of human metabolism N Swainston, K Smallbone, H Hefzi, PD Dobson, J Brewer, M Hanscho, ... Metabolomics 12, 1-7, 2016 | 309 | 2016 |
OpenFLUX: efficient modelling software for 13C-based metabolic flux analysis LE Quek, C Wittmann, LK Nielsen, JO Krömer Microbial cell factories 8, 1-15, 2009 | 300 | 2009 |
Metabolic flux analysis in mammalian cell culture LE Quek, S Dietmair, JO Krömer, LK Nielsen Metabolic engineering 12 (2), 161-171, 2010 | 269 | 2010 |
A consensus genome-scale reconstruction of Chinese hamster ovary cell metabolism H Hefzi, KS Ang, M Hanscho, A Bordbar, D Ruckerbauer, M Lakshmanan, ... Cell systems 3 (5), 434-443. e8, 2016 | 238 | 2016 |
C4GEM, a Genome-Scale Metabolic Model to Study C4 Plant Metabolism CG de Oliveira Dal’Molin, LE Quek, RW Palfreyman, SM Brumbley, ... Plant physiology 154 (4), 1871-1885, 2010 | 227 | 2010 |
Flux balance analysis of CHO cells before and after a metabolic switch from lactate production to consumption VS Martínez, S Dietmair, LE Quek, MP Hodson, P Gray, LK Nielsen Biotechnology and bioengineering 110 (2), 660-666, 2013 | 159 | 2013 |
AlgaGEM – a genome-scale metabolic reconstruction of algae based on the Chlamydomonas reinhardtii genome C Gomes de Oliveira Dal’Molin, LE Quek, RW Palfreyman, LK Nielsen BMC genomics 12, 1-10, 2011 | 157 | 2011 |
Low carbon fuels and commodity chemicals from waste gases–systematic approach to understand energy metabolism in a model acetogen E Marcellin, JB Behrendorff, S Nagaraju, S DeTissera, S Segovia, ... Green Chemistry 18 (10), 3020-3028, 2016 | 149 | 2016 |
Metabolite profiling of CHO cells with different growth characteristics S Dietmair, MP Hodson, LE Quek, NE Timmins, P Chrysanthopoulos, ... Biotechnology and bioengineering 109 (6), 1404-1414, 2012 | 140 | 2012 |
A multi-omics analysis of recombinant protein production in Hek293 cells S Dietmair, MP Hodson, LE Quek, NE Timmins, P Gray, LK Nielsen Public Library of Science 7 (8), e43394, 2012 | 138 | 2012 |
A multi-tissue genome-scale metabolic modeling framework for the analysis of whole plant systems C Gomes de Oliveira Dal'Molin, LE Quek, PA Saa, LK Nielsen Frontiers in plant science 6, 111599, 2015 | 111 | 2015 |
Epithelial-mesenchymal transition induction is associated with augmented glucose uptake and lactate production in pancreatic ductal adenocarcinoma M Liu, LE Quek, G Sultani, N Turner Cancer & metabolism 4, 1-13, 2016 | 88 | 2016 |
Loss of ceramide synthase 2 activity, necessary for myelin biosynthesis, precedes tau pathology in the cortical pathogenesis of Alzheimer's disease TA Couttas, N Kain, AK Suchowerska, LE Quek, N Turner, T Fath, ... Neurobiology of aging 43, 89-100, 2016 | 82 | 2016 |
On the reconstruction of the Mus musculus genomescale metabolic network model LE Quek, LK Nielsen Genome informatics 21, 89-100, 2008 | 75 | 2008 |
Improving culture performance and antibody production in CHO cell culture processes by reducing the Warburg effect M Buchsteiner, LE Quek, P Gray, LK Nielsen Biotechnology and bioengineering 115 (9), 2315-2327, 2018 | 73 | 2018 |
Reducing Recon 2 for steady-state flux analysis of HEK cell culture LE Quek, S Dietmair, M Hanscho, VS Martínez, N Borth, LK Nielsen Journal of biotechnology 184, 172-178, 2014 | 70 | 2014 |
Lactate production is a prioritized feature of adipocyte metabolism JR Krycer, LE Quek, D Francis, DJ Fazakerley, SD Elkington, ... Journal of Biological Chemistry 295 (1), 83-98, 2020 | 63 | 2020 |
Dynamic metabolic flux analysis using B-splines to study the effects of temperature shift on CHO cell metabolism VS Martínez, M Buchsteiner, P Gray, LK Nielsen, LE Quek Metabolic Engineering Communications 2, 46-57, 2015 | 63 | 2015 |
Dynamic metabolomics reveals that insulin primes the adipocyte for glucose metabolism JR Krycer, K Yugi, A Hirayama, DJ Fazakerley, LE Quek, R Scalzo, ... Cell reports 21 (12), 3536-3547, 2017 | 60 | 2017 |