Derek Pratt
Derek Pratt
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FSP1 is a glutathione-independent ferroptosis suppressor
S Doll, FP Freitas, R Shah, M Aldrovandi, MC da Silva, I Ingold, ...
Nature 575 (7784), 693-698, 2019
On the mechanism of cytoprotection by ferrostatin-1 and liproxstatin-1 and the role of lipid peroxidation in ferroptotic cell death
O Zilka, R Shah, B Li, JP Friedmann Angeli, M Griesser, M Conrad, ...
ACS central science 3 (3), 232-243, 2017
The chemical basis of ferroptosis
M Conrad, DA Pratt
Nature Chemical Biology 15 (12), 1137-1147, 2019
Resolving the role of lipoxygenases in the initiation and execution of ferroptosis
R Shah, MS Shchepinov, DA Pratt
ACS central science 4 (3), 387-396, 2018
Advances in radical-trapping antioxidant chemistry in the 21st century: a kinetics and mechanisms perspective
KU Ingold, DA Pratt
Chemical reviews 114 (18), 9022-9046, 2014
Ferroptosis inhibition: mechanisms and opportunities
JPF Angeli, R Shah, DA Pratt, M Conrad
Trends in pharmacological sciences 38 (5), 489-498, 2017
Metabolic determinants of cancer cell sensitivity to canonical ferroptosis inducers
M Soula, RA Weber, O Zilka, H Alwaseem, K La, F Yen, H Molina, ...
Nature Chemical Biology 16 (12), 1351-1360, 2020
Control of oxygenation in lipoxygenase and cyclooxygenase catalysis
C Schneider, DA Pratt, NA Porter, AR Brash
Chemistry & biology 14 (5), 473-488, 2007
Free radical oxidation of polyunsaturated lipids: New mechanistic insights and the development of peroxyl radical clocks
DA Pratt, KA Tallman, NA Porter
Accounts of chemical research 44 (6), 458-467, 2011
Theoretical study of X− H bond energetics (X= C, N, O, S): application to substituent effects, gas phase acidities, and redox potentials
GA DiLabio, DA Pratt, AD LoFaro, JS Wright
The Journal of Physical Chemistry A 103 (11), 1653-1661, 1999
A non-canonical vitamin K cycle is a potent ferroptosis suppressor
E Mishima, J Ito, Z Wu, T Nakamura, A Wahida, S Doll, W Tonnus, ...
Nature 608 (7924), 778-783, 2022
Critical re-evaluation of the O− H bond dissociation enthalpy in phenol
P Mulder, HG Korth, DA Pratt, GA DiLabio, L Valgimigli, GF Pedulli, ...
The Journal of Physical Chemistry A 109 (11), 2647-2655, 2005
Radicals in natural product synthesis
KJ Romero, MS Galliher, DA Pratt, CRJ Stephenson
Chemical Society Reviews 47 (21), 7851-7866, 2018
Dissecting the mechanisms of a class of chemical glycosylation using primary 13C kinetic isotope effects
M Huang, GE Garrett, N Birlirakis, L Bohé, DA Pratt, D Crich
Nature chemistry 4 (8), 663-667, 2012
Theoretical calculations of carbon− oxygen bond dissociation enthalpies of peroxyl radicals formed in the autoxidation of lipids
DA Pratt, JH Mills, NA Porter
Journal of the American Chemical Society 125 (19), 5801-5810, 2003
Garlic: source of the ultimate antioxidants–sulfenic acids
V Vaidya, KU Ingold, DA Pratt
Angew Chem Int Ed Engl 48 (1), 157-60, 2009
5-Pyrimidinols: novel chain-breaking antioxidants more effective than phenols
DA Pratt, GA DiLabio, G Brigati, GF Pedulli, L Valgimigli
Journal of the American Chemical Society 123 (19), 4625-4626, 2001
6-Amino-3-pyridinols: towards diffusion-controlled chain-breaking antioxidants
M Wijtmans, DA Pratt, L Valgimigli, GA DiLabio, GF Pedulli, NA Porter
Angewandte Chemie International Edition 42 (36), 4370-4373, 2003
Autoxidative and cyclooxygenase-2 catalyzed transformation of the dietary chemopreventive agent curcumin
M Griesser, V Pistis, T Suzuki, N Tejera, DA Pratt, C Schneider
Journal of Biological Chemistry 286 (2), 1114-1124, 2011
Bond strengths of toluenes, anilines, and phenols: to Hammett or not
DA Pratt, GA DiLabio, P Mulder, KU Ingold
Accounts of chemical research 37 (5), 334-340, 2004
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