Joe Swift
Joe Swift
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Nuclear lamin-A scales with tissue stiffness and enhances matrix-directed differentiation
J Swift, IL Ivanovska, A Buxboim, T Harada, PCDP Dingal, J Pinter, ...
Science 341 (6149), 2013
Nuclear lamin stiffness is a barrier to 3D migration, but softness can limit survival
T Harada, J Swift, J Irianto, JW Shin, KR Spinler, A Athirasala, ...
Journal of Cell Biology 204 (5), 669-682, 2014
Crawling from soft to stiff matrix polarizes the cytoskeleton and phosphoregulates myosin-II heavy chain
M Raab, J Swift, PCD P. Dingal, P Shah, JW Shin, DE Discher
Journal of Cell Biology 199 (4), 669-683, 2012
Matrix elasticity regulates lamin-A, C phosphorylation and turnover with feedback to actomyosin
A Buxboim, J Swift, J Irianto, KR Spinler, PCDP Dingal, A Athirasala, ...
Current Biology 24 (16), 1909-1917, 2014
The nuclear lamina is mechano-responsive to ECM elasticity in mature tissue
J Swift, DE Discher
Journal of cell science 127 (14), 3005-3015, 2014
Lamins regulate cell trafficking and lineage maturation of adult human hematopoietic cells
JW Shin, KR Spinler, J Swift, JA Chasis, N Mohandas, DE Discher
Proceedings of the National Academy of Sciences 110 (47), 18892-18897, 2013
Heart-specific stiffening in early embryos parallels matrix and myosin expression to optimize beating
S Majkut, T Idema, J Swift, C Krieger, A Liu, DE Discher
Current Biology 23 (23), 2434-2439, 2013
Contractile forces sustain and polarize hematopoiesis from stem and progenitor cells
JW Shin, A Buxboim, KR Spinler, J Swift, DA Christian, CA Hunter, C Léon, ...
Cell stem cell 14 (1), 81-93, 2014
Stem cell mechanobiology: diverse lessons from bone marrow
IL Ivanovska, JW Shin, J Swift, DE Discher
Trends in cell biology 25 (9), 523-532, 2015
Directing Noble Metal Ion Chemistry within a Designed Ferritin Protein,
CA Butts, J Swift, S Kang, L Di Costanzo, DW Christianson, JG Saven, ...
Biochemistry 47 (48), 12729-12739, 2008
Fractal heterogeneity in minimal matrix models of scars modulates stiff-niche stem-cell responses via nuclear exit of a mechanorepressor
PCDP Dingal, AM Bradshaw, S Cho, M Raab, A Buxboim, J Swift, ...
Nature materials 14 (9), 951-960, 2015
Structure and activity of apoferritin-stabilized gold nanoparticles
L Zhang, J Swift, CA Butts, V Yerubandi, IJ Dmochowski
Journal of Inorganic Biochemistry 101 (11-12), 1719-1729, 2007
Myosin-II inhibition and soft 2D matrix maximize multinucleation and cellular projections typical of platelet-producing megakaryocytes
JW Shin, J Swift, KR Spinler, DE Discher
Proceedings of the National Academy of Sciences 108 (28), 11458-11463, 2011
Photoinitiated destruction of composite porphyrin− protein polymersomes
GP Robbins, M Jimbo, J Swift, MJ Therien, DA Hammer, IJ Dmochowski
Journal of the American Chemical Society 131 (11), 3872-3874, 2009
Osmotic challenge drives rapid and reversible chromatin condensation in chondrocytes
J Irianto, J Swift, RP Martins, GD McPhail, MM Knight, DE Discher, DA Lee
Biophysical journal 104 (4), 759-769, 2013
Coordinated increase of nuclear tension and lamin-A with matrix stiffness outcompetes lamin-B receptor that favors soft tissue phenotypes
A Buxboim, J Irianto, J Swift, A Athirasala, JW Shin, F Rehfeldt, ...
Molecular biology of the cell 28 (23), 3333-3348, 2017
Nuclear lamins in cancer
J Irianto, CR Pfeifer, IL Ivanovska, J Swift, DE Discher
Cellular and molecular bioengineering 9 (2), 258-267, 2016
Efficient self-assembly of Archaeoglobus fulgidus ferritin around metallic cores
J Swift, CA Butts, J Cheung-Lau, V Yerubandi, IJ Dmochowski
Langmuir 25 (9), 5219-5225, 2009
Design of functional ferritin-like proteins with hydrophobic cavities
J Swift, WA Wehbi, BD Kelly, XF Stowell, JG Saven, IJ Dmochowski
Journal of the American Chemical Society 128 (20), 6611-6619, 2006
Enhancing the efficacy of drug-loaded nanocarriers against brain tumors by targeted radiation therapy
BC Baumann, GD Kao, A Mahmud, T Harada, J Swift, C Chapman, X Xu, ...
Oncotarget 4 (1), 64, 2013
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