| Insights from transgenic mouse models of ERBB2-induced breast cancer J Ursini-Siegel, B Schade, RD Cardiff, WJ Muller Nature Reviews Cancer 7 (5), 389-397, 2007 | 324 | 2007 |
| Integrated molecular profiles of invasive breast tumors and ductal carcinoma in situ (DCIS) reveal differential vascular and interleukin signaling VN Kristensen, CJ Vaske, J Ursini-Siegel, P Van Loo, SH Nordgard, ... Proceedings of the National Academy of Sciences 109 (8), 2802-2807, 2012 | 201 | 2012 |
| ShcA signalling is essential for tumour progression in mouse models of human breast cancer J Ursini‐Siegel, WR Hardy, D Zuo, SHL Lam, V Sanguin‐Gendreau, ... The EMBO journal 27 (6), 910-920, 2008 | 185 | 2008 |
| Pervasive H3K27 acetylation leads to ERV expression and a therapeutic vulnerability in H3K27M gliomas B Krug, N De Jay, AS Harutyunyan, S Deshmukh, DM Marchione, ... Cancer cell 35 (5), 782-797. e8, 2019 | 175 | 2019 |
| CDK inhibitor p18INK4c is required for the generation of functional plasma cells MR Tourigny, J Ursini-Siegel, H Lee, KM Toellner, AF Cunningham, ... Immunity 17 (2), 179-189, 2002 | 123 | 2002 |
| STAT3 establishes an immunosuppressive microenvironment during the early stages of breast carcinogenesis to promote tumor growth and metastasis LM Jones, ML Broz, JJ Ranger, J Ozcelik, R Ahn, D Zuo, J Ursini-Siegel, ... Cancer research 76 (6), 1416-1428, 2016 | 115 | 2016 |
| CD44 promotes PD-L1 expression and its tumor-intrinsic function in breast and lung cancers T Kong, R Ahn, K Yang, X Zhu, Z Fu, G Morin, R Bramley, NC Cliffe, Y Xue, ... Cancer research 80 (3), 444-457, 2020 | 109 | 2020 |
| TRAIL/Apo-2 ligand induces primary plasma cell apoptosis J Ursini-Siegel, W Zhang, A Altmeyer, EN Hatada, RKG Do, H Yagita, ... The Journal of Immunology 169 (10), 5505-5513, 2002 | 93 | 2002 |
| The prognostic ease and difficulty of invasive breast carcinoma A Tofigh, M Suderman, ER Paquet, J Livingstone, N Bertos, SM Saleh, ... Cell reports 9 (1), 129-142, 2014 | 84 | 2014 |
| Endoplasmic reticulum stress induces PRNP prion protein gene expression in breast cancer MA Déry, J Jodoin, J Ursini-Siegel, O Aleynikova, C Ferrario, S Hassan, ... Breast cancer research 15, 1-19, 2013 | 84 | 2013 |
| Translational and HIF-1α-dependent metabolic reprogramming underpin metabolic plasticity and responses to kinase inhibitors and biguanides L Hulea, SP Gravel, M Morita, M Cargnello, O Uchenunu, YK Im, ... Cell metabolism 28 (6), 817-832. e8, 2018 | 73 | 2018 |
| Lymphocyte Invasion in IC10/Basal-Like Breast Tumors Is Associated with Wild-Type TP53 D Quigley, L Silwal-Pandit, R Dannenfelser, A Langerød, HKM Vollan, ... Molecular Cancer Research 13 (3), 493-501, 2015 | 69 | 2015 |
| The influence of the pre-metastatic niche on breast cancer metastasis J Ursini-Siegel, PM Siegel Cancer letters 380 (1), 281-288, 2016 | 64 | 2016 |
| Elevated expression of DecR1 impairs ErbB2/Neu-induced mammary tumor development J Ursini-Siegel, AB Rajput, H Lu, V Sanguin-Gendreau, D Zuo, ... Molecular and Cellular Biology 27 (18), 6361-6371, 2007 | 61 | 2007 |
| The Shc1 adaptor simultaneously balances Stat1 and Stat3 activity to promote breast cancer immune suppression R Ahn, V Sabourin, AM Bolt, S Hébert, S Totten, N De Jay, MC Festa, ... Nature communications 8 (1), 14638, 2017 | 59 | 2017 |
| A complex containing LPP and α-actinin mediates TGFβ-induced migration and invasion of ErbB2-expressing breast cancer cells E Ngan, JJ Northey, CM Brown, J Ursini-Siegel, PM Siegel Journal of cell science 126 (9), 1981-1991, 2013 | 58 | 2013 |
| An integrated stress response via PKR suppresses HER2+ cancers and improves trastuzumab therapy C Darini, N Ghaddar, C Chabot, G Assaker, S Sabri, S Wang, ... Nature communications 10 (1), 2139, 2019 | 57 | 2019 |
| The ShcA adaptor protein is a critical regulator of breast cancer progression J Ursini-Siegel, WJ Muller Cell Cycle 7 (13), 1936-1943, 2008 | 53 | 2008 |
| Data-driven analysis of immune infiltrate in a large cohort of breast cancer and its association with disease progression, ER activity, and genomic complexity R Dannenfelser, M Nome, A Tahiri, J Ursini-Siegel, HKM Vollan, ... Oncotarget 8 (34), 57121, 2017 | 51 | 2017 |
| Tungsten targets the tumor microenvironment to enhance breast cancer metastasis AM Bolt, V Sabourin, MF Molina, AM Police, LF Negro Silva, D Plourde, ... Toxicological sciences 143 (1), 165-177, 2015 | 40 | 2015 |
William J. MullerProfessor, McGill UniversityVerified email at mcgill.ca
