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Andrew C. Little, Ph.D.
Andrew C. Little, Ph.D.
Verified email at boehringer-ingelheim.com
Title
Cited by
Cited by
Year
GOT1 inhibition promotes pancreatic cancer cell death by ferroptosis
DM Kremer, BS Nelson, L Lin, EL Yarosz, CJ Halbrook, SA Kerk, ...
Nature communications 12 (1), 4860, 2021
1422021
Direct cysteine sulfenylation drives activation of the Src kinase
DE Heppner, CM Dustin, C Liao, M Hristova, C Veith, AC Little, BA Ahlers, ...
Nature communications 9 (1), 4522, 2018
1082018
Robust shifts in S100a9 expression with aging: A novel mechanism for chronic inflammation
WR Swindell, A Johnston, X Xing, A Little, P Robichaud, JJ Voorhees, ...
Scientific reports 3 (1), 1215, 2013
1082013
IL-4/IL-13 stimulated macrophages enhance breast cancer invasion via rho-GTPase regulation of synergistic VEGF/CCL-18 signaling
AC Little, P Pathanjeli, Z Wu, L Bao, LE Goo, JA Yates, CR Oliver, ...
Frontiers in Oncology 9, 456, 2019
762019
DUOX1 silencing in lung cancer promotes EMT, cancer stem cell characteristics and invasive properties
AC Little, D Sham, M Hristova, K Danyal, DE Heppner, RA Bauer, ...
Oncogenesis 5 (10), e261-e261, 2016
622016
High-content fluorescence imaging with the metabolic flux assay reveals insights into mitochondrial properties and functions
AC Little, I Kovalenko, LE Goo, HS Hong, SA Kerk, JA Yates, V Purohit, ...
Communications biology 3 (1), 271, 2020
562020
Paradoxical roles of dual oxidases in cancer biology
AC Little, A Sulovari, K Danyal, DE Heppner, DJ Seward, A van der Vliet
Free Radical Biology and Medicine 110, 117-132, 2017
442017
Breast cancers utilize hypoxic glycogen stores via PYGB, the brain isoform of glycogen phosphorylase, to promote metastatic phenotypes
MA Altemus, LE Goo, AC Little, JA Yates, HG Cheriyan, ZF Wu, ...
PloS one 14 (9), e0220973, 2019
402019
Acrolein and thiol-reactive electrophiles suppress allergen-induced innate airway epithelial responses by inhibition of DUOX1 and EGFR
K Danyal, W de Jong, E O'Brien, RA Bauer, DE Heppner, AC Little, ...
American Journal of Physiology-Lung Cellular and Molecular Physiology 311 (5 …, 2016
192016
Dysregulated redox regulation contributes to nuclear EGFR localization and pathogenicity in lung cancer
AC Little, M Hristova, L van Lith, C Schiffers, CM Dustin, A Habibovic, ...
Scientific Reports 9 (1), 4844, 2019
182019
Internalized FGF-2-loaded nanoparticles increase nuclear ERK1/2 content and result in lung cancer cell death
T Miao, AC Little, A Aronshtam, T Marquis, SL Fenn, M Hristova, ...
Nanomaterials 10 (4), 612, 2020
112020
Robust shifts in S100a9 expression with aging: a novel mechanism for chronic inflammation. Sci Rep. 2013; 3: 1215
WR Swindell, A Johnston, X Xing, A Little, P Robichaud, JJ Voorhees, ...
7
RhoC modulates cell junctions and Type I interferon response in aggressive breast cancers
HG Abraham, PJ Ulintz, L Goo, JA Yates, AC Little, L Bao, Z Wu, ...
Frontiers in Oncology 11, 712041, 2021
32021
DUOX1 expression in lung cancer disrupts pro-oncogenic activation mechanisms and localization of Src and EGFR
AC Little, K Danyal, RA Bauer, DE Heppner, M Hristova, C Dustin, ...
Cancer Research 76 (14_Supplement), 1681-1681, 2016
22016
IL-4/IL-13 stimulated tumor-associated macrophages enhance breast cancer cell invasion through Rho-GTPase signaling
AC Little, P Pathanjeli, Z Wu, L Bao, L Goo, JA Yates, SD Merajver
Cancer Research 79 (13_Supplement), 4518-4518, 2019
12019
Development of an Enhanced-Throughput Radial Cell Migration Device
CR Oliver, AC Little, TM Westerhof, P Pathanjeli, JA Yates, SD Merajver
SLAS TECHNOLOGY: Translating Life Sciences Innovation 26 (2), 200-208, 2021
2021
RhoC decreases tight junction stabilization in breast cancer cells, revealing a potential therapeutic target
H Abraham, L Goo, A Little, J Yates, Z Wu, SD Merajver
Cancer Research 80 (16_Supplement), 2616-2616, 2020
2020
Development of a high-throughput radial migration device
CR Oliver, AC Little, TM Westerhof, P Pathanjeli, JA Yates, SD Merajver
bioRxiv, 2020.01. 31.928879, 2020
2020
Integration of high-content fluorescence imaging into the metabolic flux assay reveals insights into mitochondrial properties and functions
AC Little, I Kovalenko, LE Goo, HS Hong, SA Kerk, JA Yates, V Purohit, ...
bioRxiv, 758110, 2019
2019
Effects of the small GTPase RhoC on inflammatory breast cancer metabolism
LE Goo, JA Yates, AC Little, D Kremer, I Kovalenko, CR Oliver, ...
Cancer Research 79 (13_Supplement), 4363-4363, 2019
2019
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