GOT1 inhibition promotes pancreatic cancer cell death by ferroptosis DM Kremer, BS Nelson, L Lin, EL Yarosz, CJ Halbrook, SA Kerk, ... Nature communications 12 (1), 4860, 2021 | 142 | 2021 |
Direct cysteine sulfenylation drives activation of the Src kinase DE Heppner, CM Dustin, C Liao, M Hristova, C Veith, AC Little, BA Ahlers, ... Nature communications 9 (1), 4522, 2018 | 108 | 2018 |
Robust shifts in S100a9 expression with aging: A novel mechanism for chronic inflammation WR Swindell, A Johnston, X Xing, A Little, P Robichaud, JJ Voorhees, ... Scientific reports 3 (1), 1215, 2013 | 108 | 2013 |
IL-4/IL-13 stimulated macrophages enhance breast cancer invasion via rho-GTPase regulation of synergistic VEGF/CCL-18 signaling AC Little, P Pathanjeli, Z Wu, L Bao, LE Goo, JA Yates, CR Oliver, ... Frontiers in Oncology 9, 456, 2019 | 76 | 2019 |
DUOX1 silencing in lung cancer promotes EMT, cancer stem cell characteristics and invasive properties AC Little, D Sham, M Hristova, K Danyal, DE Heppner, RA Bauer, ... Oncogenesis 5 (10), e261-e261, 2016 | 62 | 2016 |
High-content fluorescence imaging with the metabolic flux assay reveals insights into mitochondrial properties and functions AC Little, I Kovalenko, LE Goo, HS Hong, SA Kerk, JA Yates, V Purohit, ... Communications biology 3 (1), 271, 2020 | 56 | 2020 |
Paradoxical roles of dual oxidases in cancer biology AC Little, A Sulovari, K Danyal, DE Heppner, DJ Seward, A van der Vliet Free Radical Biology and Medicine 110, 117-132, 2017 | 44 | 2017 |
Breast cancers utilize hypoxic glycogen stores via PYGB, the brain isoform of glycogen phosphorylase, to promote metastatic phenotypes MA Altemus, LE Goo, AC Little, JA Yates, HG Cheriyan, ZF Wu, ... PloS one 14 (9), e0220973, 2019 | 40 | 2019 |
Acrolein and thiol-reactive electrophiles suppress allergen-induced innate airway epithelial responses by inhibition of DUOX1 and EGFR K Danyal, W de Jong, E O'Brien, RA Bauer, DE Heppner, AC Little, ... American Journal of Physiology-Lung Cellular and Molecular Physiology 311 (5 …, 2016 | 19 | 2016 |
Dysregulated redox regulation contributes to nuclear EGFR localization and pathogenicity in lung cancer AC Little, M Hristova, L van Lith, C Schiffers, CM Dustin, A Habibovic, ... Scientific Reports 9 (1), 4844, 2019 | 18 | 2019 |
Internalized FGF-2-loaded nanoparticles increase nuclear ERK1/2 content and result in lung cancer cell death T Miao, AC Little, A Aronshtam, T Marquis, SL Fenn, M Hristova, ... Nanomaterials 10 (4), 612, 2020 | 11 | 2020 |
Robust shifts in S100a9 expression with aging: a novel mechanism for chronic inflammation. Sci Rep. 2013; 3: 1215 WR Swindell, A Johnston, X Xing, A Little, P Robichaud, JJ Voorhees, ... | 7 | |
RhoC modulates cell junctions and Type I interferon response in aggressive breast cancers HG Abraham, PJ Ulintz, L Goo, JA Yates, AC Little, L Bao, Z Wu, ... Frontiers in Oncology 11, 712041, 2021 | 3 | 2021 |
DUOX1 expression in lung cancer disrupts pro-oncogenic activation mechanisms and localization of Src and EGFR AC Little, K Danyal, RA Bauer, DE Heppner, M Hristova, C Dustin, ... Cancer Research 76 (14_Supplement), 1681-1681, 2016 | 2 | 2016 |
IL-4/IL-13 stimulated tumor-associated macrophages enhance breast cancer cell invasion through Rho-GTPase signaling AC Little, P Pathanjeli, Z Wu, L Bao, L Goo, JA Yates, SD Merajver Cancer Research 79 (13_Supplement), 4518-4518, 2019 | 1 | 2019 |
Development of an Enhanced-Throughput Radial Cell Migration Device CR Oliver, AC Little, TM Westerhof, P Pathanjeli, JA Yates, SD Merajver SLAS TECHNOLOGY: Translating Life Sciences Innovation 26 (2), 200-208, 2021 | | 2021 |
RhoC decreases tight junction stabilization in breast cancer cells, revealing a potential therapeutic target H Abraham, L Goo, A Little, J Yates, Z Wu, SD Merajver Cancer Research 80 (16_Supplement), 2616-2616, 2020 | | 2020 |
Development of a high-throughput radial migration device CR Oliver, AC Little, TM Westerhof, P Pathanjeli, JA Yates, SD Merajver bioRxiv, 2020.01. 31.928879, 2020 | | 2020 |
Integration of high-content fluorescence imaging into the metabolic flux assay reveals insights into mitochondrial properties and functions AC Little, I Kovalenko, LE Goo, HS Hong, SA Kerk, JA Yates, V Purohit, ... bioRxiv, 758110, 2019 | | 2019 |
Effects of the small GTPase RhoC on inflammatory breast cancer metabolism LE Goo, JA Yates, AC Little, D Kremer, I Kovalenko, CR Oliver, ... Cancer Research 79 (13_Supplement), 4363-4363, 2019 | | 2019 |