Addressing proteolytic efficiency in enzymatic degradation therapy for celiac disease M Rey, M Yang, L Lee, Y Zhang, JG Sheff, CW Sensen, H Mrazek, ... Scientific reports 6 (1), 30980, 2016 | 65 | 2016 |
Peptide–column interactions and their influence on back exchange rates in hydrogen/deuterium exchange-MS JG Sheff, M Rey, DC Schriemer Journal of the American Society for Mass Spectrometry 24 (7), 1006-1015, 2013 | 60 | 2013 |
Lactoferrin binding protein B–a bi-functional bacterial receptor protein NKH Ostan, RH Yu, D Ng, CCL Lai, AK Pogoutse, V Sarpe, M Hepburn, ... PLoS pathogens 13 (3), e1006244, 2017 | 35 | 2017 |
Nanospray HX-MS configuration for structural interrogation of large protein systems JG Sheff, M Hepburn, Y Yu, SP Lees-Miller, DC Schriemer Analyst 142 (6), 904-910, 2017 | 24 | 2017 |
Structures and dynamics of native-state transmembrane protein targets and bound lipids M Overduin, C Trieber, RS Prosser, LP Picard, JG Sheff Membranes 11 (6), 451, 2021 | 19 | 2021 |
Novel allosteric pathway of Eg5 regulation identified through multivariate statistical analysis of hydrogen-exchange mass spectrometry (HX-MS) ligand screening data JG Sheff, F Farshidfar, OF Bathe, K Kopciuk, F Gentile, J Tuszynski, ... Molecular & Cellular Proteomics 16 (3), 428-437, 2017 | 18 | 2017 |
Arsenal of nanobodies shows broad-spectrum neutralization against SARS-CoV-2 variants of concern in vitro and in vivo in hamster models MA Rossotti, H van Faassen, AT Tran, J Sheff, JK Sandhu, D Duque, ... Communications Biology 5 (1), 933, 2022 | 16* | 2022 |
Defining the epitope of a blood–brain barrier crossing single domain antibody specific for the type 1 insulin-like growth factor receptor J Sheff, P Wang, P Xu, M Arbour, L Masson, H van Faassen, G Hussack, ... Scientific Reports 11 (1), 4284, 2021 | 15 | 2021 |
Binding symmetry and surface flexibility mediate antibody self-association JD Schrag, MÈ Picard, F Gaudreault, LP Gagnon, J Baardsnes, ... MAbs 11 (7), 1300-1318, 2019 | 11 | 2019 |
Toward standardizing deuterium content reporting in hydrogen exchange-MS JG Sheff, DC Schriemer Analytical chemistry 86 (24), 11962-11965, 2014 | 8 | 2014 |
Hydrogen-deuterium exchange mass spectrometry reveals three unique binding responses of mAbs directed to the catalytic domain of hCAIX JG Sheff, JF Kelly, A Robotham, T Sulea, F Malenfant, D L’Abbé, ... MAbs 13 (1), 1997072, 2021 | 3 | 2021 |
Epitope mapping of a blood–brain barrier crossing antibody targeting the cysteine-rich region of IGF1R using hydrogen-exchange mass spectrometry enabled by electrochemical … J Sheff, J Kelly, M Foss, E Brunette, K Kemmerich, H van Faassen, ... The Journal of Biochemistry 173 (2), 95-105, 2023 | 1 | 2023 |
Influence of variant-specific mutations, temperature and pH on conformations of a large set of SARS-CoV-2 spike trimer vaccine antigen candidates M Stuible, JD Schrag, J Sheff, D Zoubchenok, S Lord-Dufour, B Cass, ... Scientific Reports 13 (1), 16498, 2023 | | 2023 |
Author Correction: Addressing proteolytic efficiency in enzymatic degradation therapy for celiac disease M Rey, M Yang, L Lee, Y Zhang, JG Sheff, CW Sensen, H Mrazek, ... Scientific Reports 13 (1), 956, 2023 | | 2023 |
Arsenal of Nanobodies for Broad-Spectrum Countermeasures against Current and Future SARS-CoV-2 Variants of Concerns (preprint) MA Rossotti, H van Faassen, A Tran, J Sheff, JA Sandhu, D Duque, ... | | 2021 |
Towards Probing Structure and Function Relationships of Proteins in Complex Sample Types Using HX-MS J Sheff University of Calgary, 2017 | | 2017 |