PI(3,4,5)P3 and PI(4,5)P2 Lipids Target Proteins with Polybasic Clusters to the Plasma Membrane WD Heo, T Inoue, WS Park, ML Kim, BO Park, TJ Wandless, T Meyer Science 314 (5804), 1458-1461, 2006 | 878 | 2006 |
Live-cell imaging reveals sequential oligomerization and local plasma membrane targeting of stromal interaction molecule 1 after Ca2+ store depletion J Liou, M Fivaz, T Inoue, T Meyer Proceedings of the National Academy of Sciences 104 (22), 9301-9306, 2007 | 748 | 2007 |
Rapid chemically induced changes of PtdIns (4, 5) P2 gate KCNQ ion channels BC Suh, T Inoue, T Meyer, B Hille Science 314 (5804), 1454-1457, 2006 | 554 | 2006 |
An inducible translocation strategy to rapidly activate and inhibit small GTPase signaling pathways T Inoue, WD Heo, JS Grimley, TJ Wandless, T Meyer Nature methods 2 (6), 415-418, 2005 | 451 | 2005 |
A phosphorylation-dependent intramolecular interaction regulates the membrane association and activity of the tumor suppressor PTEN M Rahdar, T Inoue, T Meyer, J Zhang, F Vazquez, PN Devreotes Proceedings of the National Academy of Sciences 106 (2), 480-485, 2009 | 318 | 2009 |
Dynamic remodeling of membrane composition drives cell cycle through primary cilia excision SC Phua, S Chiba, M Suzuki, E Su, EC Roberson, GV Pusapati, M Setou, ... Cell 168 (1), 264-279. e15, 2017 | 304 | 2017 |
Phosphoinositides regulate ciliary protein trafficking to modulate hedgehog signaling FR Garcia-Gonzalo, SC Phua, EC Roberson, G Garcia, M Abedin, ... Developmental cell 34 (4), 400-409, 2015 | 292 | 2015 |
Rapid and orthogonal logic gating with a gibberellin-induced dimerization system T Miyamoto, R DeRose, A Suarez, T Ueno, M Chen, T Sun, MJ Wolfgang, ... Nature chemical biology 8 (5), 465-470, 2012 | 236 | 2012 |
Manipulating signaling at will: chemically-inducible dimerization (CID) techniques resolve problems in cell biology R DeRose, T Miyamoto, T Inoue Pflügers Archiv-European Journal of Physiology 465, 409-417, 2013 | 232 | 2013 |
Synthesizing biomolecule-based Boolean logic gates T Miyamoto, S Razavi, R DeRose, T Inoue ACS synthetic biology 2 (2), 72-82, 2013 | 177 | 2013 |
Synthetic activation of endogenous PI3K and Rac identifies an AND-gate switch for cell polarization and migration T Inoue, T Meyer PloS one 3 (8), e3068, 2008 | 164 | 2008 |
A photocleavable rapamycin conjugate for spatiotemporal control of small GTPase activity N Umeda, T Ueno, C Pohlmeyer, T Nagano, T Inoue Journal of the American Chemical Society 133 (1), 12-14, 2011 | 161 | 2011 |
Organelle-specific, rapid induction of molecular activities and membrane tethering T Komatsu, I Kukelyansky, JM McCaffery, T Ueno, LC Varela, T Inoue Nature methods 7 (3), 206-208, 2010 | 161 | 2010 |
Genetically encoded calcium indicator illuminates calcium dynamics in primary cilia S Su, SC Phua, R DeRose, S Chiba, K Narita, PN Kalugin, T Katada, ... Nature methods 10 (11), 1105-1107, 2013 | 144 | 2013 |
Real-time measurements of protein dynamics using fluorescence activation-coupled protein labeling method T Komatsu, K Johnsson, H Okuno, H Bito, T Inoue, T Nagano, Y Urano Journal of the American Chemical Society 133 (17), 6745-6751, 2011 | 143 | 2011 |
Robust neuronal symmetry breaking by Ras-triggered local positive feedback M Fivaz, S Bandara, T Inoue, T Meyer Current biology 18 (1), 44-50, 2008 | 140 | 2008 |
Chemically inducible diffusion trap at cilia reveals molecular sieve–like barrier YC Lin, P Niewiadomski, B Lin, H Nakamura, SC Phua, J Jiao, ... Nature chemical biology 9 (7), 437-443, 2013 | 137 | 2013 |
Altering the threshold of an excitable signal transduction network changes cell migratory modes Y Miao, S Bhattacharya, M Edwards, H Cai, T Inoue, PA Iglesias, ... Nature cell biology 19 (4), 329-340, 2017 | 127 | 2017 |
The CP110-interacting proteins Talpid3 and Cep290 play overlapping and distinct roles in cilia assembly T Kobayashi, S Kim, YC Lin, T Inoue, BD Dynlacht Journal of Cell Biology 204 (2), 215-229, 2014 | 122 | 2014 |
Intracellular production of hydrogels and synthetic RNA granules by multivalent molecular interactions H Nakamura, AA Lee, AS Afshar, S Watanabe, E Rho, S Razavi, A Suarez, ... Nature materials 17 (1), 79-89, 2018 | 120 | 2018 |