| Chromosomal instability drives metastasis through a cytosolic DNA response SF Bakhoum, B Ngo, AM Laughney, JA Cavallo, CJ Murphy, P Ly, P Shah, ... Nature 553 (7689), 467-472, 2018 | 1198 | 2018 |
| Targeting cancer vulnerabilities with high-dose vitamin C B Ngo, JM Van Riper, LC Cantley, J Yun Nature Reviews Cancer 19 (5), 271-282, 2019 | 337 | 2019 |
| Limited environmental serine and glycine confer brain metastasis sensitivity to PHGDH inhibition B Ngo, E Kim, V Osorio-Vasquez, S Doll, S Bustraan, RJ Liang, A Luengo, ... Cancer discovery 10 (9), 1352-1373, 2020 | 170 | 2020 |
| Targeting tumor suppressor networks for cancer therapeutics X Emily Guo, B Ngo, A Sandaldjian Modrek, WH Lee Current drug targets 15 (1), 2-16, 2014 | 121 | 2014 |
| Induction of APOBEC3 exacerbates DNA replication stress and chromosomal instability in early breast and lung cancer evolution S Venkatesan, M Angelova, C Puttick, H Zhai, DR Caswell, WT Lu, ... Cancer discovery 11 (10), 2456-2473, 2021 | 85 | 2021 |
| Phosphorylation of the Ndc80 complex protein, HEC1, by Nek2 kinase modulates chromosome alignment and signaling of the spindle assembly checkpoint R Wei, B Ngo, G Wu, WH Lee Molecular biology of the cell 22 (19), 3584-3594, 2011 | 82 | 2011 |
| Novel small molecules disrupting Hec1/Nek2 interaction ablate tumor progression by triggering Nek2 degradation through a death-trap mechanism CM Hu, J Zhu, XE Guo, W Chen, XL Qiu, B Ngo, R Chien, YV Wang, ... Oncogene 34 (10), 1220-1230, 2015 | 53 | 2015 |
| Aurora-A phosphorylates Augmin complex component Hice1 protein at an N-terminal serine/threonine cluster to modulate its microtubule binding activity during spindle assembly CY Tsai, B Ngo, A Tapadia, PH Hsu, G Wu, WH Lee Journal of Biological Chemistry 286 (34), 30097-30106, 2011 | 43 | 2011 |
| Oncologic impact of micrometastases or isolated tumor cells in sentinel lymph nodes of patients with endometrial cancer: a meta-analysis NR Gómez-Hidalgo, PT Ramirez, B Ngo, S Pérez-Hoyos, N Coreas, ... Clinical and Translational Oncology 22, 1272-1279, 2020 | 36 | 2020 |
| Hec1 contributes to mitotic centrosomal microtubule growth for proper spindle assembly through interaction with Hice1 G Wu, R Wei, E Cheng, B Ngo, WH Lee Molecular biology of the cell 20 (22), 4686-4695, 2009 | 21 | 2009 |
| GLUT5 (SLC2A5) enables fructose-mediated proliferation independent of ketohexokinase RJ Liang, S Taylor, N Nahiyaan, J Song, CJ Murphy, E Dantas, S Cheng, ... Cancer & Metabolism 9, 1-13, 2021 | 19 | 2021 |
| LKB1-dependent regulation of TPI1 creates a divergent metabolic liability between human and mouse lung adenocarcinoma BD Stein, JR Ferrarone, EE Gardner, JW Chang, D Wu, PE Hollstein, ... Cancer discovery 13 (4), 1002-1025, 2023 | 5 | 2023 |
| Complementary interhelical interactions between three buried Glu-Lys pairs within three heptad repeats are essential for Hec1-Nuf2 heterodimerization and mitotic progression B Ngo, CM Hu, XE Guo, B Ngo, R Wei, J Zhu, WH Lee Journal of Biological Chemistry 288 (48), 34403-34413, 2013 | 3 | 2013 |
| Loss of Pip4k2c confers liver-metastatic organotropism through insulin-dependent PI3K-AKT pathway activation M Rogava, TJ Aprati, WY Chi, JC Melms, C Hug, SH Davis, EM Earlie, ... Nature Cancer, 1-15, 2024 | 2 | 2024 |
| Non-conserved metabolic regulation by LKB1 distinguishes human and mouse lung adenocarcinoma BD Stein, JR Ferrarone, EE Gardner, JW Chang, D Wu, Q Chen, ... bioRxiv, 2021.10. 01.462764, 2021 | 1 | 2021 |
| Targeting chromosomal instability and downstream cytosolic dna signaling for cancer treatment LC Cantley, B Ngo, SF Bakhoum US Patent App. 18/299,558, 2024 | | 2024 |
| Targeting chromosomal instability and downstream cytosolic DNA signaling for cancer treatment LC Cantley, B Ngo, SF Bakhoum US Patent 11,821,042, 2023 | | 2023 |
| A genetic-metabolic circuit of liver-specific metastatic organotropism M Rogava, TJ Aprati, WY Chen, J Melms, C Hug, AD Amin, B Ngo, M Lee, ... Cancer Research 83 (7_Supplement), 3514-3514, 2023 | | 2023 |
| Protein State‐Dependent Chemical Biology KA Scott, TL Zhang, SY Xi, B Ngo, EV Vinogradova Israel Journal of Chemistry 63 (3-4), e202200101, 2023 | | 2023 |
| A genetic-metabolic axis of metastatic liver organotropism M Rogava, JC Melms, S Davis, C Hug, B Ngo, MJ Lee, P Ho, AD Amin, ... Cancer Research 82 (12_Supplement), 981-981, 2022 | | 2022 |
Lewis CantleyDana Farber Cancer Center and Harvard Medical SchoolVerified email at med.cornell.edu
