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Yann Le Guen
Yann Le Guen
Verified email at stanford.edu - Homepage
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Cited by
Year
Association of Klotho-VS heterozygosity with risk of Alzheimer disease in individuals who carry APOE4
ME Belloy, V Napolioni, SS Han, Y Le Guen, MD Greicius, ...
JAMA neurology 77 (7), 849-862, 2020
922020
Exome sequencing identifies rare damaging variants in ATP8B4 and ABCA1 as risk factors for Alzheimer’s disease
H Holstege, M Hulsman, C Charbonnier, B Grenier-Boley, O Quenez, ...
Nature genetics 54 (12), 1786-1794, 2022
91*2022
Genetic influence on the sulcal pits: on the origin of the first cortical folds
Y Le Guen, G Auzias, F Leroy, M Noulhiane, G Dehaene-Lambertz, ...
Cerebral Cortex 28 (6), 1922-1933, 2018
652018
Association of rare APOE missense variants V236E and R251G with risk of Alzheimer disease
Y Le Guen, ME Belloy, B Grenier-Boley, I De Rojas, A Castillo-Morales, ...
JAMA neurology 79 (7), 652-663, 2022
432022
PyPNS: Multiscale simulation of a peripheral nerve in python
CH Lubba, Y Le Guen, S Jarvis, NS Jones, SC Cork, A Eftekhar, ...
Neuroinformatics 17, 63-81, 2019
382019
Organ aging signatures in the plasma proteome track health and disease
HSH Oh, J Rutledge, D Nachun, R Pálovics, O Abiose, P Moran-Losada, ...
Nature 624 (7990), 164-172, 2023
352023
Common X‐chromosome variants are associated with Parkinson disease risk
Y Le Guen, V Napolioni, ME Belloy, E Yu, L Krohn, JA Ruskey, Z Gan‐Or, ...
Annals of neurology 90 (1), 22-34, 2021
332021
“Plis de passage” deserve a role in models of the cortical folding process
JF Mangin, Y Le Guen, N Labra, A Grigis, V Frouin, M Guevara, C Fischer, ...
Brain topography 32 (6), 1035-1048, 2019
322019
The chaotic morphology of the left superior temporal sulcus is genetically constrained
Y Le Guen, F Leroy, G Auzias, D Riviere, A Grigis, JF Mangin, O Coulon, ...
NeuroImage 174, 297-307, 2018
312018
eQTL of KCNK2 regionally influences the brain sulcal widening: evidence from 15,597 UK Biobank participants with neuroimaging data
Y Le Guen, C Philippe, D Riviere, H Lemaitre, A Grigis, C Fischer, ...
Brain Structure and Function 224 (2), 847-857, 2019
282019
Identification of putative causal loci in whole-genome sequencing data via knockoff statistics
Z He, L Liu, C Wang, Y Le Guen, J Lee, S Gogarten, F Lu, S Montgomery, ...
Nature communications 12 (1), 3152, 2021
262021
A novel age-informed approach for genetic association analysis in Alzheimer’s disease
Y Le Guen, ME Belloy, V Napolioni, SJ Eger, G Kennedy, R Tao, Z He, ...
Alzheimer's Research & Therapy 13, 1-14, 2021
202021
Shared genetic aetiology between cognitive performance and brain activations in language and math tasks
Y Le Guen, M Amalric, P Pinel, C Pallier, V Frouin
Scientific Reports 8 (1), 17624, 2018
192018
Association of African Ancestry–Specific APOE Missense Variant R145C With Risk of Alzheimer Disease
Y Le Guen, AC Raulin, MW Logue, R Sherva, ME Belloy, SJ Eger, A Chen, ...
JAMA 329 (7), 551-560, 2023
18*2023
Genome-wide analysis of common and rare variants via multiple knockoffs at biobank scale, with an application to Alzheimer disease genetics
Z He, Y Le Guen, L Liu, J Lee, S Ma, AC Yang, X Liu, J Rutledge, ...
The American Journal of Human Genetics 108 (12), 2336-2353, 2021
182021
Enhancer locus in ch14q23. 1 modulates brain asymmetric temporal regions involved in language processing
Y Le Guen, F Leroy, C Philippe, Imagen Consortium, JF Mangin, ...
Cerebral Cortex 30 (10), 5322-5332, 2020
182020
Performance of a fully-automated Lumipulse plasma phospho-tau181 assay for Alzheimer’s disease
EN Wilson, CB Young, J Ramos Benitez, MS Swarovski, I Feinstein, ...
Alzheimer's Research & Therapy 14 (1), 172, 2022
172022
APOE genotype and Alzheimer disease risk across age, sex, and population ancestry
ME Belloy, SJ Andrews, Y Le Guen, M Cuccaro, LA Farrer, V Napolioni, ...
JAMA neurology 80 (12), 1284-1294, 2023
142023
KL∗ VS heterozygosity reduces brain amyloid in asymptomatic at-risk APOE∗ 4 carriers
ME Belloy, SJ Eger, Y Le Guen, V Napolioni, KD Deters, HS Yang, ...
Neurobiology of aging 101, 123-129, 2021
132021
Multiancestry analysis of the HLA locus in Alzheimer’s and Parkinson’s diseases uncovers a shared adaptive immune response mediated by HLA-DRB1*04 subtypes
Y Le Guen, G Luo, A Ambati, V Damotte, I Jansen, E Yu, A Nicolas, ...
Proceedings of the National Academy of Sciences 120 (36), e2302720120, 2023
11*2023
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