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Rachel Truitt
Rachel Truitt
Verified email at pennmedicine.upenn.edu
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Year
SARS-CoV-2 induces double-stranded RNA-mediated innate immune responses in respiratory epithelial-derived cells and cardiomyocytes
Y Li, DM Renner, CE Comar, JN Whelan, HM Reyes, FL Cardenas-Diaz, ...
Proceedings of the National Academy of Sciences 118 (16), e2022643118, 2021
2132021
Drug repurposing screens reveal cell-type-specific entry pathways and FDA-approved drugs active against SARS-Cov-2
M Dittmar, JS Lee, K Whig, E Segrist, M Li, B Kamalia, L Castellana, ...
Cell reports 35 (1), 2021
1682021
Vascular endothelial growth factor and substrate mechanics regulate in vitro tubulogenesis of endothelial progenitor cells
D Hanjaya‐Putra, J Yee, D Ceci, R Truitt, D Yee, S Gerecht
Journal of cellular and molecular medicine 14 (10), 2436-2447, 2010
1622010
Adaptation to oxygen deprivation in cultures of human pluripotent stem cells, endothelial progenitor cells, and umbilical vein endothelial cells
HE Abaci, R Truitt, E Luong, G Drazer, S Gerecht
American Journal of Physiology-Cell Physiology 298 (6), C1527-C1537, 2010
1232010
SARS-CoV-2 disrupts host epigenetic regulation via histone mimicry
J Kee, S Thudium, DM Renner, K Glastad, K Palozola, Z Zhang, Y Li, ...
Nature 610 (7931), 381-388, 2022
822022
Mechanically dynamic PDMS substrates to investigate changing cell environments
YC Yeh, EA Corbin, SR Caliari, L Ouyang, SL Vega, R Truitt, L Han, ...
Biomaterials 145, 23-32, 2017
812017
Unforeseen decreases in dissolved oxygen levels affect tube formation kinetics in collagen gels
HE Abaci, R Truitt, S Tan, S Gerecht
American Journal of Physiology-Cell Physiology 301 (2), C431-C440, 2011
562011
Increased afterload augments sunitinib-induced cardiotoxicity in an engineered cardiac microtissue model
R Truitt, A Mu, EA Corbin, A Vite, J Brandimarto, B Ky, KB Margulies
JACC: Basic to Translational Science 3 (2), 265-276, 2018
522018
SARS-CoV-2 infection enhances mitochondrial PTP complex activity to perturb cardiac energetics
K Ramachandran, S Maity, AR Muthukumar, S Kandala, D Tomar, ...
IScience 25 (1), 2022
312022
Responsiveness to perturbations is a hallmark of transcription factors that maintain cell identity in vitro
IA Mellis, HI Edelstein, R Truitt, Y Goyal, LE Beck, O Symmons, ...
Cell systems 12 (9), 885-899. e8, 2021
202021
Cell type determination for cardiac differentiation occurs soon after seeding of human-induced pluripotent stem cells
CL Jiang, Y Goyal, N Jain, Q Wang, RE Truitt, AJ Coté, B Emert, IA Mellis, ...
Genome biology 23 (1), 90, 2022
192022
Drug repurposing screens reveal cell-type-specific entry pathways and FDA-approved drugs active against SARS-Cov-2. Cell Rep 35: 108959
M Dittmar, JS Lee, K Whig, E Segrist, M Li, B Kamalia, L Castellana, ...
162021
Acute frataxin knockdown in induced pluripotent stem cell-derived cardiomyocytes activates a type I interferon response
MG Cotticelli, S Xia, R Truitt, NM Doliba, AV Rozo, JW Tobias, T Lee, ...
Disease models & mechanisms 16 (5), dmm049497, 2023
72023
SARS-CoV-2 ORF8 encoded protein contains a histone mimic, disrupts chromatin regulation, and enhances replication
J Kee, S Thudium, D Renner, K Glastad, K Palozola, Z Zhang, Y Li, ...
bioRxiv, 2021.11. 10.468057, 2021
72021
Author Correction: SARS-CoV-2 disrupts host epigenetic regulation via histone mimicry
J Kee, S Thudium, DM Renner, K Glastad, K Palozola, Z Zhang, Y Li, ...
Nature 614 (7949), E44, 2023
12023
Responsiveness to perturbations is a hallmark of transcription factors that maintain cell identity
IA Mellis, HI Edelstein, R Truitt, LE Beck, O Symmons, Y Goyal, ...
Biorxiv, 2020.06. 11.147207, 2020
12020
SARS-CoV-2 disrupts host epigenetic regulation via histone mimicry (vol 610, pg 381, 2022)
J Kee, S Thudium, DMM Renner, K Glastad, K Palozola, Z Zhang, Y Li, ...
NATURE, 2023
2023
Activation of a type I interferon response associated with acute frataxin knockdown in iPSC-derived cardiomyocytes.
MG Cotticelli, S Xia, R Truitt, NM Doliba, AV Rozo, JW Tobias, T Lee, ...
Disease Models & Mechanisms, dmm. 049497-dmm. 049497, 2022
2022
SARS-CoV-2 protein encoded by ORF8 contains a histone mimic that disrupts chromatin regulation
J Kee, S Thudium, K Glastad, K Palozola, Z Zhang, Y Li, J Cesare, R Truitt, ...
2021
SARS-CoV-2 ORF8 encoded protein contains a histone mimic, disrupts chromatin regulation, and enhances replication (preprint)
J Kee, S Thudium, D Renner, K Glastad, K Palozola, Z Zhang, Y Li, ...
2021
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