Mostoslavsky, Raul
Mostoslavsky, Raul
The Massachusetts General Hospital Cancer Center-Harvard Medical School
Verified email at
Cited by
Cited by
Stress-dependent regulation of FOXO transcription factors by the SIRT1 deacetylase
A Brunet, LB Sweeney, JF Sturgill, KF Chua, PL Greer, Y Lin, H Tran, ...
science 303 (5666), 2011-2015, 2004
Genomic instability and aging-like phenotype in the absence of mammalian SIRT6
R Mostoslavsky, KF Chua, DB Lombard, WW Pang, MR Fischer, L Gellon, ...
Cell 124 (2), 315-329, 2006
Recent progress in the biology and physiology of sirtuins
T Finkel, CX Deng, R Mostoslavsky
Nature 460 (7255), 587-591, 2009
Metabolic control of muscle mitochondrial function and fatty acid oxidation through SIRT1/PGC‐1α
Z Gerhart‐Hines, JT Rodgers, O Bare, C Lerin, SH Kim, R Mostoslavsky, ...
The EMBO journal 26 (7), 1913-1923, 2007
A role for the NAD-dependent deacetylase Sirt1 in the regulation of autophagy
IH Lee, L Cao, R Mostoslavsky, DB Lombard, J Liu, NE Bruns, M Tsokos, ...
Proceedings of the National Academy of Sciences 105 (9), 3374-3379, 2008
SIRT1 regulates circadian clock gene expression through PER2 deacetylation
G Asher, D Gatfield, M Stratmann, H Reinke, C Dibner, F Kreppel, ...
Cell 134 (2), 317-328, 2008
Developmental defects and p53 hyperacetylation in Sir2 homolog (SIRT1)-deficient mice
HL Cheng, R Mostoslavsky, S Saito, JP Manis, Y Gu, P Patel, R Bronson, ...
Proceedings of the National Academy of Sciences 100 (19), 10794-10799, 2003
SIRT4 inhibits glutamate dehydrogenase and opposes the effects of calorie restriction in pancreatic β cells
MC Haigis, R Mostoslavsky, KM Haigis, K Fahie, DC Christodoulou, ...
Cell 126 (5), 941-954, 2006
Mammalian Sir2 homolog SIRT3 regulates global mitochondrial lysine acetylation
DB Lombard, FW Alt, HL Cheng, J Bunkenborg, RS Streeper, ...
Molecular and cellular biology 27 (24), 8807-8814, 2007
DNA repair, genome stability, and aging
DB Lombard, KF Chua, R Mostoslavsky, S Franco, M Gostissa, FW Alt
Cell 120 (4), 497-512, 2005
The histone deacetylase Sirt6 regulates glucose homeostasis via Hif1α
L Zhong, A D'Urso, D Toiber, C Sebastian, RE Henry, DD Vadysirisack, ...
Cell 140 (2), 280-293, 2010
SIRT1 redistribution on chromatin promotes genomic stability but alters gene expression during aging
P Oberdoerffer, S Michan, M McVay, R Mostoslavsky, J Vann, SK Park, ...
Cell 135 (5), 907-918, 2008
Mechanism and control of V (D) J recombination at the immunoglobulin heavy chain locus
D Jung, C Giallourakis, R Mostoslavsky, FW Alt
Annu. Rev. Immunol. 24, 541-570, 2006
SIRT1 controls endothelial angiogenic functions during vascular growth
M Potente, L Ghaeni, D Baldessari, R Mostoslavsky, L Rossig, F Dequiedt, ...
Genes & development 21 (20), 2644-2658, 2007
SIRT6 regulates TNF-α secretion through hydrolysis of long-chain fatty acyl lysine
H Jiang, S Khan, Y Wang, G Charron, B He, C Sebastian, J Du, R Kim, ...
Nature 496 (7443), 110-113, 2013
The histone deacetylase SIRT6 is a tumor suppressor that controls cancer metabolism
C Sebastián, BMM Zwaans, DM Silberman, M Gymrek, A Goren, L Zhong, ...
Cell 151 (6), 1185-1199, 2012
The sirtuin SIRT6 blocks IGF-Akt signaling and development of cardiac hypertrophy by targeting c-Jun
NR Sundaresan, P Vasudevan, L Zhong, G Kim, S Samant, V Parekh, ...
Nature medicine 18 (11), 1643-1650, 2012
Acetylation-dependent regulation of endothelial Notch signalling by the SIRT1 deacetylase
V Guarani, G Deflorian, CA Franco, M Krüger, LK Phng, K Bentley, ...
Nature 473 (7346), 234-238, 2011
Conserved role of SIRT1 orthologs in fasting-dependent inhibition of the lipid/cholesterol regulator SREBP
AK Walker, F Yang, K Jiang, JY Ji, JL Watts, A Purushotham, O Boss, ...
Genes & development 24 (13), 1403-1417, 2010
SIRT6 recruits SNF2H to DNA break sites, preventing genomic instability through chromatin remodeling
D Toiber, F Erdel, K Bouazoune, DM Silberman, L Zhong, P Mulligan, ...
Molecular cell 51 (4), 454-468, 2013
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