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Chenxi Xu
Chenxi Xu
Verified email at duke.edu - Homepage
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Cited by
Year
Repression of hypoxia-inducible factor α signaling by Set7-mediated methylation
X Liu, Z Chen, C Xu, X Leng, H Cao, G Ouyang, W Xiao
Nucleic acids research 43 (10), 5081-5098, 2015
1082015
Zebrafish foxo3b negatively regulates antiviral response through suppressing the transactivity of irf3 and irf7
X Liu, X Cai, D Zhang, C Xu, W Xiao
The Journal of Immunology 197 (12), 4736-4749, 2016
522016
SIRT5 impairs aggregation and activation of the signaling adaptor MAVS through catalyzing lysine desuccinylation
X Liu, C Zhu, H Zha, J Tang, F Rong, X Chen, S Fan, C Xu, J Du, J Zhu, ...
The EMBO Journal 39 (11), e103285, 2020
402020
A NSD3-targeted PROTAC suppresses NSD3 and cMyc oncogenic nodes in cancer cells
C Xu, F Meng, KS Park, AJ Storey, W Gong, YH Tsai, E Gibson, SD Byrum, ...
Cell chemical biology 29 (3), 386-397. e9, 2022
342022
A pathogen-derived effector modulates host glucose metabolism by arginine GlcNAcylation of HIF-1α protein
C Xu, X Liu, H Zha, S Fan, D Zhang, S Li, W Xiao
PLoS pathogens 14 (8), e1007259, 2018
332018
Zebrafish prmt5 arginine methyltransferase is essential for germ cell development
J Zhu, D Zhang, X Liu, G Yu, X Cai, C Xu, F Rong, G Ouyang, J Wang, ...
Development 146 (20), dev179572, 2019
262019
Cistrome analysis of YY1 uncovers a regulatory axis of YY1: BRD2/4-PFKP during tumorigenesis of advanced prostate cancer
C Xu, YH Tsai, PM Galbo Jr, W Gong, AJ Storey, Y Xu, SD Byrum, L Xu, ...
Nucleic acids research 49 (9), 4971-4988, 2021
242021
Neddylation facilitates the antiviral response in zebrafish
G Yu, X Liu, J Tang, C Xu, G Ouyang, W Xiao
Frontiers in Immunology 10, 1432, 2019
232019
Discovery of a first-in-class degrader for nuclear receptor binding SET domain protein 2 (NSD2) and Ikaros/Aiolos
F Meng, C Xu, KS Park, HU Kaniskan, GG Wang, J Jin
Journal of medicinal chemistry 65 (15), 10611-10625, 2022
182022
TET is targeted for proteasomal degradation by the PHD-pVHL pathway to reduce DNA hydroxymethylation
S Fan, J Wang, G Yu, F Rong, D Zhang, C Xu, J Du, Z Li, G Ouyang, ...
Journal of Biological Chemistry 295 (48), 16299-16313, 2020
142020
Discovery of a potent and selective targeted NSD2 degrader for the reduction of H3K36me2
RP Hanley, DY Nie, JR Tabor, F Li, A Sobh, C Xu, NK Barker, D Dilworth, ...
Journal of the American Chemical Society 145 (14), 8176-8188, 2023
132023
Interaction between androgen receptor and coregulator SLIRP is regulated by Ack1 tyrosine kinase and androgen
D De Silva, Z Zhang, Y Liu, JS Parker, C Xu, L Cai, GG Wang, HS Earp, ...
Scientific Reports 9 (1), 18637, 2019
82019
SET7 methylates the deubiquitinase OTUB1 at Lys 122 to impair its binding to E2 enzyme UBC13 and relieve its suppressive role on ferroptosis
H Deng, S Jia, J Tang, F Rong, C Xu, X Chen, Z Wang, C Zhu, X Sun, ...
Journal of Biological Chemistry 299 (4), 2023
52023
Onco-condensates: formation, multi-component organization, and biological functions
C Xu, A Kim, JM Corbin, GG Wang
Trends in Cancer 9 (9), 738-751, 2023
42023
TNRC18 engages H3K9me3 to mediate silencing of endogenous retrotransposons
S Zhao, J Lu, B Pan, H Fan, SD Byrum, C Xu, A Kim, Y Guo, KL Kanchi, ...
Nature 623 (7987), 633-642, 2023
32023
Zebrafish prmt5 arginine methyltransferase is essential for germ cell development (vol 146, dev179572, 2019)
J Zhu, D Zhang, X Liu, G Yu, X Cai, C Xu, F Rong, G Ouyang, J Wang, ...
DEVELOPMENT 147 (10), 2020
22020
Epigenetic (De) regulation in Prostate Cancer
C Xu, S Zhao, L Cai
Epigenetics in Oncology, 321-360, 2023
2023
YY1 cistrome analysis uncovers an essential requirement of the YY1: BRD4-PFKP regulatory axis for promoting tumorigenesis of castration-resistant prostate cancer
C Xu, YH Tsai, P Galbo, W Gong, AJ Storey, Y Xu, SD Byrum, YE Whang, ...
bioRxiv, 2020.09. 17.302596, 2020
2020
Correction: Zebrafish prmt5 arginine methyltransferase is essential for germ cell development
J Zhu, D Zhang, X Liu, G Yu, X Cai, C Xu, F Rong, G Ouyang, J Wang, ...
Development 147 (10), dev191692, 2020
2020
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