Charles Ishak
Charles Ishak
Assistant Professor. University of Texas MD Anderson Cancer Center
Verified email at - Homepage
Cited by
Cited by
Epigenetic therapy induces transcription of inverted SINEs and ADAR1 dependency
P Mehdipour, SA Marhon, I Ettayebi, A Chakravarthy, A Hosseini, Y Wang, ...
Nature 588 (7836), 169-173, 2020
An RB-EZH2 Complex Mediates Silencing of Repetitive DNA Sequences
CA Ishak, AE Marshall, DT Passos, CR White, SJ Kim, MJ Cecchini, ...
Molecular Cell 64 (6), 1074-1087, 2016
Endogenous retroelements and the viral mimicry response in cancer therapy and cellular homeostasis
R Chen, CA Ishak, DD De Carvalho
Cancer discovery 11 (11), 2707-2725, 2021
Haploinsufficiency of an RB–E2F1–Condensin II complex leads to aberrant replication and aneuploidy
CH Coschi, CA Ishak, D Gallo, A Marshall, S Talluri, J Wang, MJ Cecchini, ...
Cancer discovery 4 (7), 840-853, 2014
Deregulation of retroelements as an emerging therapeutic opportunity in cancer
CA Ishak, M Classon, DD De Carvalho
Trends in cancer 4 (8), 583-597, 2018
DNA hypomethylating agents increase activation and cytolytic activity of CD8+ T cells
HL Yau, E Bell, I Ettayebi, FC de Almeida, GM Boukhaled, SY Shen, ...
Molecular cell 81 (7), 1469-1483. e8, 2021
An open-label, phase II multicohort study of an oral hypomethylating agent CC-486 and durvalumab in advanced solid tumors
K Taylor, HL Yau, A Chakravarthy, B Wang, SY Shen, I Ettayebi, CA Ishak, ...
Journal for immunotherapy of cancer 8 (2), 2020
Reactivation of endogenous retroelements in cancer development and therapy
CA Ishak, DD De Carvalho
Annual Review of Cancer Biology 4, 159-176, 2020
Loss of the mammalian DREAM complex deregulates chondrocyte proliferation
C Forristal, SA Henley, JI MacDonald, JR Bush, C Ort, DT Passos, ...
Molecular and cellular biology 34 (12), 2221-2234, 2014
Modeling methyl-sensitive transcription factor motifs with an expanded epigenetic alphabet
C Viner, CA Ishak, J Johnson, NJ Walker, H Shi, MK Sj÷berg-Herrera, ...
Genome biology 25 (1), 11, 2024
Haploinsufficiency of RREB1 causes a Noonan-like RASopathy via epigenetic reprogramming of RAS-MAPK pathway genes
OA Kent, M Saha, E Coyaud, HE Burston, N Law, K Dadson, S Chen, ...
Nature communications 11 (1), 4673, 2020
Disruption of CDK-resistant chromatin association by pRB causes DNA damage, mitotic errors, and reduces Condensin II recruitment
CA Ishak, CH Coschi, MV Roes, FA Dick
Cell Cycle 16 (15), 1430-1439, 2017
Loss of the retinoblastoma tumor suppressor correlates with improved outcome in patients with lung adenocarcinoma treated with surgery and chemotherapy
MJ Cecchini, CA Ishak, DT Passos, A Warner, DA Palma, CJ Howlett, ...
Human Pathology 46 (12), 1922-1934, 2015
DNA methylation as a robust classifier of epithelial ovarian cancer
CA Ishak, S Lheureux, DD De Carvalho
Clinical Cancer Research 25 (19), 5729-5731, 2019
An RB-condensin II complex mediates long-range chromosome interactions and influences expression at divergently paired genes
AE Marshall, CA Ishak, FA Dick
Molecular and cellular biology, 2020
Spliceosome-targeted therapies induce dsRNA responses
CA Ishak, HL Yau, DD De Carvalho
Immunity 54 (1), 11-13, 2021
Conditional haploinsufficiency of the retinoblastoma tumor suppressor gene
CA Ishak, FA Dick
Molecular & Cellular Oncology 2 (1), e968069, 2015
Publisher Correction: Epigenetic therapy induces transcription of inverted SINEs and ADAR1 dependency (Nature,(2020), 588, 7836,(169-173), 10.1038/s41586-020-2844-1)
P Mehdipour, SA Marhon, I Ettayebi, A Chakravarthy, A Hosseini, Y Wang, ...
Nature 591 (7850), E20, 2021
DNA methylation profiling of premalignant lesions as a path to ovarian cancer early detection
CA Ishak, DD De Carvalho
Clinical Cancer Research 26 (23), 6083-6085, 2020
Retroelement decay by the exonuclease XRN1 is a viral mimicry dependency in cancer
A Hosseini, HT Lindholm, R Chen, P Mehdipour, SA Marhon, CA Ishak, ...
Cell Reports 43 (2), 2024
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