Inconsistency in large pharmacogenomic studies B Haibe-Kains, N El-Hachem, NJ Birkbak, AC Jin, AH Beck, HJWL Aerts, ... Nature 504 (7480), 389-393, 2013 | 561 | 2013 |
Defining the biological basis of radiomic phenotypes in lung cancer P Grossmann, O Stringfield, N El-Hachem, MM Bui, E Rios Velazquez, ... elife 6, e23421, 2017 | 322 | 2017 |
PharmacoGx: an R package for analysis of large pharmacogenomic datasets P Smirnov, Z Safikhani, N El-Hachem, D Wang, A She, C Olsen, ... Bioinformatics 32 (8), 1244-1246, 2016 | 263 | 2016 |
mRMRe: an R package for parallelized mRMR ensemble feature selection N De Jay, S Papillon-Cavanagh, C Olsen, N El-Hachem, G Bontempi, ... Bioinformatics 29 (18), 2365-2368, 2013 | 254 | 2013 |
Acute inflammatory response via neutrophil activation protects against the development of chronic pain M Parisien, LV Lima, C Dagostino, N El-Hachem, GL Drury, AV Grant, ... Science translational medicine 14 (644), eabj9954, 2022 | 152 | 2022 |
PharmacoDB: an integrative database for mining in vitro anticancer drug screening studies P Smirnov, V Kofia, A Maru, M Freeman, C Ho, N El-Hachem, GA Adam, ... Nucleic acids research 46 (D1), D994-D1002, 2018 | 140 | 2018 |
AutoDock and AutoDockTools for protein-ligand docking: beta-site amyloid precursor protein cleaving enzyme 1 (BACE1) as a case study N El-Hachem, B Haibe-Kains, A Khalil, FH Kobeissy, G Nemer Neuroproteomics: Methods and Protocols, 391-403, 2017 | 117 | 2017 |
Revisiting inconsistency in large pharmacogenomic studies Z Safikhani, P Smirnov, M Freeman, N El-Hachem, A She, Q Rene, ... F1000Research 5, 2016 | 115 | 2016 |
Comparison and validation of genomic predictors for anticancer drug sensitivity S Papillon-Cavanagh, N De Jay, N Hachem, C Olsen, G Bontempi, ... Journal of the American Medical Informatics Association 20 (4), 597-602, 2013 | 82 | 2013 |
Gene isoforms as expression-based biomarkers predictive of drug response in vitro Z Safikhani, P Smirnov, KL Thu, J Silvester, N El-Hachem, R Quevedo, ... Nature communications 8 (1), 1126, 2017 | 70 | 2017 |
Genetic pathway analysis reveals a major role for extracellular matrix organization in inflammatory and neuropathic pain M Parisien, A Samoshkin, SN Tansley, MH Piltonen, LJ Martin, ... Pain 160 (4), 932-944, 2019 | 62 | 2019 |
Public data and open source tools for multi-assay genomic investigation of disease L Kannan, M Ramos, A Re, N El-Hachem, Z Safikhani, DMA Gendoo, ... Briefings in bioinformatics 17 (4), 603-615, 2016 | 61 | 2016 |
Integrative cancer pharmacogenomics to infer large-scale drug taxonomy N El-Hachem, DMA Gendoo, LS Ghoraie, Z Safikhani, P Smirnov, ... Cancer research 77 (11), 3057-3069, 2017 | 41 | 2017 |
AXL knockdown gene signature reveals a drug repurposing opportunity for a class of antipsychotics to reduce growth and metastasis of triple-negative breast cancer MA Goyette, R Cusseddu, I Elkholi, A Abu-Thuraia, N El-Hachem, ... Oncotarget 10 (21), 2055, 2019 | 39 | 2019 |
Assessment of pharmacogenomic agreement Z Safikhani, N El-Hachem, R Quevedo, P Smirnov, A Goldenberg, ... F1000Research 5, 2016 | 38 | 2016 |
A HAND to TBX5 explains the link between thalidomide and cardiac diseases A Khalil, R Tanos, N El-Hachem, M Kurban, P Bouvagnet, F Bitar, ... Scientific Reports 7 (1), 1416, 2017 | 32 | 2017 |
Regulation of de novo ceramide synthesis: the role of dihydroceramide desaturase and transcriptional factors NFATC and Hand2 in the hypoxic mouse heart R Azzam, F Hariri, N El-Hachem, A Kamar, G Dbaibo, G Nemer, F Bitar DNA and cell biology 32 (6), 310-319, 2013 | 25 | 2013 |
Thiazole derivatives as inhibitors of cyclooxygenases in vitro and in vivo GA El-Achkar, M Jouni, MF Mrad, T Hirz, N El Hachem, A Khalaf, ... European journal of pharmacology 750, 66-73, 2015 | 24 | 2015 |
Importance of collection in gene set enrichment analysis of drug response in cancer cell lines AR Bateman, N El-Hachem, AH Beck, HJWL Aerts, B Haibe-Kains Scientific reports 4 (1), 4092, 2014 | 24 | 2014 |
Safikhani et al. reply Z Safikhani, N El-Hachem, P Smirnov, M Freeman, A Goldenberg, ... Nature 540 (7631), E2-E4, 2016 | 23 | 2016 |