| Early increase in extrasynaptic NMDA receptor signaling and expression contributes to phenotype onset in Huntington's disease mice AJ Milnerwood, CM Gladding, MA Pouladi, AM Kaufman, RM Hines, ... Neuron 65 (2), 178-190, 2010 | 560 | 2010 |
| Translation initiator EIF4G1 mutations in familial Parkinson disease MC Chartier-Harlin, JC Dachsel, C Vilariño-Güell, SJ Lincoln, F Leprêtre, ... The American Journal of Human Genetics 89 (3), 398-406, 2011 | 368 | 2011 |
| DNAJC13 mutations in Parkinson disease C Vilariño-Güell, A Rajput, AJ Milnerwood, B Shah, C Szu-Tu, J Trinh, I Yu, ... Human molecular genetics 23 (7), 1794-1801, 2014 | 336 | 2014 |
| Pathophysiology of Huntington's disease: time-dependent alterations in synaptic and receptor function LA Raymond, VM André, C Cepeda, CM Gladding, AJ Milnerwood, ... Neuroscience 198, 252-273, 2011 | 335 | 2011 |
| Early synaptic pathophysiology in neurodegeneration: insights from Huntington's disease AJ Milnerwood, LA Raymond Trends in neurosciences 33 (11), 513-523, 2010 | 330 | 2010 |
| Progressive dopaminergic alterations and mitochondrial abnormalities in LRRK2 G2019S knock-in mice M Yue, KM Hinkle, P Davies, E Trushina, FC Fiesel, TA Christenson, ... Neurobiology of disease 78, 172-195, 2015 | 235 | 2015 |
| G2019S-LRRK2 expression augments α-synuclein sequestration into inclusions in neurons LA Volpicelli-Daley, H Abdelmotilib, Z Liu, L Stoyka, JPL Daher, ... Journal of Neuroscience 36 (28), 7415-7427, 2016 | 189 | 2016 |
| Opposing roles of synaptic and extrasynaptic NMDA receptor signaling in cocultured striatal and cortical neurons AM Kaufman, AJ Milnerwood, MD Sepers, A Coquinco, K She, L Wang, ... Journal of Neuroscience 32 (12), 3992-4003, 2012 | 178 | 2012 |
| Synaptic dysfunction in progranulin-deficient mice TL Petkau, SJ Neal, A Milnerwood, A Mew, AM Hill, P Orban, J Gregg, ... Neurobiology of disease 45 (2), 711-722, 2012 | 166 | 2012 |
| Early development of aberrant synaptic plasticity in a mouse model of Huntington's disease AJ Milnerwood, DM Cummings, GM Dallérac, JY Brown, SC Vatsavayai, ... Human molecular genetics 15 (10), 1690-1703, 2006 | 162 | 2006 |
| Retromer-dependent neurotransmitter receptor trafficking to synapses is altered by the Parkinson's disease VPS35 mutation p. D620N LN Munsie, AJ Milnerwood, P Seibler, DA Beccano-Kelly, I Tatarnikov, ... Human molecular genetics 24 (6), 1691-1703, 2015 | 141 | 2015 |
| Corticostriatal synaptic function in mouse models of Huntington's disease: early effects of huntingtin repeat length and protein load AJ Milnerwood, LA Raymond The Journal of physiology 585 (3), 817-831, 2007 | 141 | 2007 |
| Palmitoylation of δ-catenin by DHHC5 mediates activity-induced synapse plasticity GS Brigidi, Y Sun, D Beccano-Kelly, K Pitman, M Mobasser, SL Borgland, ... Nature neuroscience 17 (4), 522-532, 2014 | 138 | 2014 |
| Aberrant cortical synaptic plasticity and dopaminergic dysfunction in a mouse model of Huntington's disease DM Cummings, AJ Milnerwood, GM Dallerac, V Waights, JY Brown, ... Human molecular genetics 15 (19), 2856-2868, 2006 | 124 | 2006 |
| Synaptic function is modulated by LRRK2 and glutamate release is increased in cortical neurons of G2019S LRRK2 knock-in mice DA Beccano-Kelly, N Kuhlmann, I Tatarnikov, M Volta, LN Munsie, ... Frontiers in cellular neuroscience 8, 301, 2014 | 123 | 2014 |
| Altered palmitoylation and neuropathological deficits in mice lacking HIP14 RR Singaraja, K Huang, SS Sanders, AJ Milnerwood, R Hines, JP Lerch, ... Human molecular genetics 20 (20), 3899-3909, 2011 | 122 | 2011 |
| LRRK2 overexpression alters glutamatergic presynaptic plasticity, striatal dopamine tone, postsynaptic signal transduction, motor activity and memory DA Beccano-Kelly, M Volta, LN Munsie, SA Paschall, I Tatarnikov, K Co, ... Human molecular genetics 24 (5), 1336-1349, 2015 | 103 | 2015 |
| P38 MAPK is involved in enhanced NMDA receptor-dependent excitotoxicity in YAC transgenic mouse model of Huntington disease J Fan, CM Gladding, L Wang, LYJ Zhang, AM Kaufman, AJ Milnerwood, ... Neurobiology of disease 45 (3), 999-1009, 2012 | 100 | 2012 |
| Progranulin deficiency decreases gross neural connectivity but enhances transmission at individual synapses L Tapia, A Milnerwood, A Guo, F Mills, E Yoshida, C Vasuta, ... Journal of Neuroscience 31 (31), 11126-11132, 2011 | 98 | 2011 |
| Calpain and STriatal-Enriched protein tyrosine phosphatase (STEP) activation contribute to extrasynaptic NMDA receptor localization in a Huntington's disease mouse model CM Gladding, MD Sepers, J Xu, LYJ Zhang, AJ Milnerwood, PJ Lombroso, ... Human molecular genetics 21 (17), 3739-3752, 2012 | 92 | 2012 |
Lynn A RaymondProfessor of Psychiatry, University of British Columbia, Huntington Study Group, Predict-HDVerified email at exchange.ubc.ca
