A systems biology perspective on sVEGFR1: its biological function, pathogenic role and therapeutic use FTH Wu, MO Stefanini, FM Gabhann, CD Kontos, BH Annex, AS Popel Journal of cellular and molecular medicine 14 (3), 528-552, 2010 | 270 | 2010 |
A compartment model of VEGF distribution in blood, healthy and diseased tissues MO Stefanini, FTH Wu, F Mac Gabhann, AS Popel BMC systems biology 2, 1-25, 2008 | 183 | 2008 |
Increase of plasma VEGF after intravenous administration of bevacizumab is predicted by a pharmacokinetic model MO Stefanini, FTH Wu, F Mac Gabhann, AS Popel Cancer research 70 (23), 9886-9894, 2010 | 92 | 2010 |
A compartment model of VEGF distribution in humans in the presence of soluble VEGF receptor-1 acting as a ligand trap FTH Wu, MO Stefanini, F Mac Gabhann, AS Popel PloS one 4 (4), e5108, 2009 | 76 | 2009 |
The presence of VEGF receptors on the luminal surface of endothelial cells affects VEGF distribution and VEGF signaling MO Stefanini, FTH Wu, F Mac Gabhann, AS Popel PLoS computational biology 5 (12), e1000622, 2009 | 66 | 2009 |
Evidence implicating immunological host effects in the efficacy of metronomic low-dose chemotherapy Y Shaked, E Pham, S Hariharan, K Magidey, O Beyar-Katz, P Xu, S Man, ... Cancer Research 76 (20), 5983-5993, 2016 | 55 | 2016 |
Efficacy of cotargeting angiopoietin-2 and the VEGF pathway in the adjuvant postsurgical setting for early breast, colorectal, and renal cancers FTH Wu, S Man, P Xu, A Chow, M Paez-Ribes, CR Lee, ... Cancer research 76 (23), 6988-7000, 2016 | 54 | 2016 |
VEGF and soluble VEGF receptor-1 (sFlt-1) distributions in peripheral arterial disease: an in silico model FTH Wu, MO Stefanini, FM Gabhann, CD Kontos, BH Annex, AS Popel American Journal of Physiology-Heart and Circulatory Physiology 298 (6 …, 2010 | 52 | 2010 |
Vasculotide reduces endothelial permeability and tumor cell extravasation in the absence of binding to or agonistic activation of Tie2 FTH Wu, CR Lee, E Bogdanovic, A Prodeus, J Gariépy, RS Kerbel EMBO molecular medicine 7 (6), 770-787, 2015 | 41 | 2015 |
Quantitative characterization of metastatic disease in the spine. Part II. Histogram‐based analyses C Whyne, M Hardisty, F Wu, T Skrinskas, M Clemons, L Gordon, ... Medical physics 34 (8), 3279-3285, 2007 | 40 | 2007 |
Pre-and post-operative anti-PD-L1 plus anti-angiogenic therapies in mouse breast or renal cancer models of micro-or macro-metastatic disease FTH Wu, P Xu, A Chow, S Man, J Krüger, KA Khan, M Paez-Ribes, ... British journal of cancer 120 (2), 196-206, 2019 | 30 | 2019 |
Ang2 inhibitors and Tie2 activators: potential therapeutics in perioperative treatment of early stage cancer KA Khan, FTH Wu, W Cruz‐Munoz, RS Kerbel EMBO Molecular Medicine 13 (7), e08253, 2021 | 24 | 2021 |
Computational kinetic model of VEGF trapping by soluble VEGF receptor-1: effects of transendothelial and lymphatic macromolecular transport FTH Wu, MO Stefanini, F Mac Gabhann, CD Kontos, BH Annex, AS Popel Physiological genomics 38 (1), 29-41, 2009 | 22 | 2009 |
Computational representation of the aponeuroses as NURBS surfaces in 3D musculoskeletal models FTH Wu, V Ng-Thow-Hing, K Singh, AM Agur, NH McKee computer methods and programs in biomedicine 88 (2), 112-122, 2007 | 20 | 2007 |
Modeling of growth factor-receptor systems: from molecular-level protein interaction networks to whole-body compartment models FTH Wu, MO Stefanini, F Mac Gabhann, AS Popel Methods in enzymology 467, 461-497, 2009 | 18 | 2009 |
Aflibercept and Ang1 supplementation improve neoadjuvant or adjuvant chemotherapy in a preclinical model of resectable breast cancer FTH Wu, M Paez-Ribes, P Xu, S Man, E Bogdanovic, G Thurston, ... Scientific Reports 6 (1), 36694, 2016 | 17 | 2016 |
Automated atlas-based 3D segmentation of the metastatic spine L Gordon, M Hardisty, T Skrinskas, F Wu, C Whyne Orthopaedic Proceedings 90 (SUPP_I), 128-128, 2008 | 8 | 2008 |
Targeting the Angiopoietin-Tie2 Pathway to Inhibit Early-Stage Cancer Metastasis FTH Wu University of Toronto (Canada), 2017 | 1 | 2017 |
QUANTITATIVE CHARACTERIZATION OF METASTATIC PROGRESSION IN THE SPINE THROUGH AUTOMATED CT ANALYSIS F Wu, D Burnes, L Gordon, M Hardisty, T Skrinskas, P Basran, C Whyne Orthopaedic Proceedings 90 (SUPP_I), 129-129, 2008 | 1 | 2008 |
Primer on systemic therapies for advanced lung cancers in 2023 F Wu, C Ho Journal of Family Practice Oncology, ISSN 2369-4173 (Online) www.fpon.ca, 25-27, 2023 | | 2023 |