Doxycycline plus tauroursodeoxycholic acid for transthyretin amyloidosis: a phase II study L Obici, A Cortese, A Lozza, J Lucchetti, M Gobbi, G Palladini, S Perlini, ... Amyloid 19 (sup1), 34-36, 2012 | 246 | 2012 |
Selective nanovector mediated treatment of activated proinflammatory microglia/macrophages in spinal cord injury S Papa, F Rossi, R Ferrari, A Mariani, M De Paola, I Caron, F Fiordaliso, ... ACS nano 7 (11), 9881-9895, 2013 | 151 | 2013 |
Early modulation of pro-inflammatory microglia by minocycline loaded nanoparticles confers long lasting protection after spinal cord injury S Papa, I Caron, E Erba, N Panini, M De Paola, A Mariani, C Colombo, ... Biomaterials 75, 13-24, 2016 | 123 | 2016 |
Applications of surface plasmon resonance (SPR) for the characterization of nanoparticles developed for biomedical purposes M Canovi, J Lucchetti, M Stravalaci, F Re, D Moscatelli, P Bigini, ... Sensors 12 (12), 16420-16432, 2012 | 75 | 2012 |
Plasma and brain concentrations of doxycycline after single and repeated doses in wild-type and APP23 mice J Lucchetti, C Fracasso, C Balducci, A Passoni, G Forloni, M Salmona, ... Journal of Pharmacology and Experimental Therapeutics 368 (1), 32-40, 2019 | 54 | 2019 |
Ranolazine prevents INaL enhancement and blunts myocardial remodelling in a model of pulmonary hypertension M Rocchetti, L Sala, R Rizzetto, LI Staszewsky, M Alemanni, V Zambelli, ... Cardiovascular research 104 (1), 37-48, 2014 | 52 | 2014 |
Early activation of the kynurenine pathway predicts early death and long‐term outcome in patients resuscitated from out‐of‐hospital cardiac arrest G Ristagno, R Latini, J Vaahersalo, S Masson, J Kurola, T Varpula, ... Journal of the American Heart Association 3 (4), e001094, 2014 | 48 | 2014 |
Benefit of doxycycline treatment on articular disability caused by dialysis related amyloidosis G Montagna, B Cazzulani, L Obici, C Uggetti, S Giorgetti, R Porcari, ... Amyloid 20 (3), 173-178, 2013 | 34 | 2013 |
Biophysical and in vivo studies identify a new natural-based polyphenol, counteracting Aβ oligomerization in vitro and Aβ oligomer-mediated memory impairment and … S Tomaselli, P La Vitola, K Pagano, E Brandi, G Santamaria, D Galante, ... ACS Chemical Neuroscience 10 (11), 4462-4475, 2019 | 24 | 2019 |
Ventilation with argon improves survival with good neurological recovery after prolonged untreated cardiac arrest in pigs F Fumagalli, D Olivari, A Boccardo, D De Giorgio, R Affatato, S Ceriani, ... Journal of the American Heart Association 9 (24), e016494, 2020 | 22 | 2020 |
A new surface plasmon resonance-based immunoassay for rapid, reproducible and sensitive quantification of pentraxin-3 in human plasma M Canovi, J Lucchetti, M Stravalaci, S Valentino, B Bottazzi, M Salmona, ... Sensors 14 (6), 10864-10875, 2014 | 21 | 2014 |
A Mouse Model of Familial ALS Has Increased CNS Levels of Endogenous Ubiquinol9/10 and Does Not Benefit from Exogenous Administration of Ubiquinol10 J Lucchetti, M Marino, S Papa, M Tortarolo, G Guiso, S Pozzi, V Bonetto, ... PLoS One 8 (7), e69540, 2013 | 16 | 2013 |
A validated, sensitive HPLC‐MS/MS method for quantification of cis‐para‐methyl‐4‐methylaminorex (cis‐4,4'‐DMAR) in rat and human plasma: application to … J Lucchetti, CM Marzo, A Di Clemente, L Cervo, M Gobbi Drug Testing and Analysis 9 (6), 870-879, 2017 | 10 | 2017 |
A novel bio-inspired strategy to prevent amyloidogenesis and synaptic damage in Alzheimer’s disease M Catania, L Colombo, S Sorrentino, A Cagnotto, J Lucchetti, ... Molecular psychiatry 27 (12), 5227-5234, 2022 | 8 | 2022 |
Doxycycline rescues recognition memory and circadian motor rhythmicity but does not prevent terminal disease in fatal familial insomnia mice G Lavigna, A Masone, I Bouybayoune, I Bertani, J Lucchetti, M Gobbi, ... Neurobiology of Disease 158, 105455, 2021 | 7 | 2021 |
Doxycycline inhibition of a pseudotyped virus transduction does not translate to inhibition of SARS-CoV-2 infectivity L Diomede, S Baroni, A De Luigi, A Piotti, J Lucchetti, C Fracasso, ... Viruses 13 (9), 1745, 2021 | 6 | 2021 |
Brain disposition, metabolism and behavioral effects of the synthetic opioid AH-7921 in rats J Lucchetti, CM Marzo, A Passoni, F Moro, A di Clemente, R Bagnati, ... Neuropharmacology 133, 51-62, 2018 | 5 | 2018 |
Brain disposition of cis-para-methyl-4-methylaminorex (cis-4,4'-DMAR) and its potential metabolites after acute and chronic treatment in rats: correlation with central … J Lucchetti, C Marzo, A Passoni, A Di Clemente, F Moro, R Bagnati, ... Journal of Pharmacology and Experimental Therapeutics, 2017 | 4 | 2017 |
Brain kynurenine pathway and functional outcome of rats resuscitated from cardiac arrest J Lucchetti, F Fumagalli, D Olivari, R Affatato, C Fracasso, D De Giorgio, ... Journal of the American Heart Association 10 (23), e021071, 2021 | 3 | 2021 |
SEPN1-related myopathy depends on the oxidoreductase ERO1A and is druggable with the chemical chaperone TUDCA S Germani, AT Van Ho, A Cherubini, E Varone, A Chernorudskiy, ... Cell Reports Medicine, 2024 | 1 | 2024 |