| Current status of methods for defining the applicability domain of (quantitative) structure-activity relationships: The report and recommendations of ecvam workshop 52 TI Netzeva, AP Worth, T Aldenberg, R Benigni, MTD Cronin, P Gramatica, ... Alternatives to Laboratory Animals 33 (2), 155-173, 2005 | 685 | 2005 |
| Mechanistic applicability domain classification of a local lymph node assay dataset for skin sensitization DW Roberts, G Patlewicz, PS Kern, F Gerberick, I Kimber, RJ Dearman, ... Chemical Research in Toxicology 20 (7), 1019-1030, 2007 | 645 | 2007 |
| Compilation of historical local lymph node data for evaluation of skin sensitization alternative methods FG Gerberick, CA Ryan, PS Kern, H Schlatter, RJ Dearman, I Kimber, ... Dermatitis 16 (4), 157-202, 2005 | 409 | 2005 |
| ToxCast chemical landscape: paving the road to 21st century toxicology AM Richard, RS Judson, KA Houck, CM Grulke, P Volarath, ... Chemical research in toxicology 29 (8), 1225-1251, 2016 | 281 | 2016 |
| A stepwise approach for defining the applicability domain of SAR and QSAR models S Dimitrov, G Dimitrova, T Pavlov, N Dimitrova, G Patlewicz, J Niemela, ... Journal of chemical information and modeling 45 (4), 839-849, 2005 | 274 | 2005 |
| An evaluation of the implementation of the Cramer classification scheme in the Toxtree software G Patlewicz, N Jeliazkova, RJ Safford, AP Worth, B Aleksiev SAR and QSAR in Environmental Research 19 (5-6), 495-524, 2008 | 240 | 2008 |
| Applying adverse outcome pathways (AOPs) to support integrated approaches to testing and assessment (IATA) KE Tollefsen, S Scholz, MT Cronin, SW Edwards, J de Knecht, K Crofton, ... Regulatory Toxicology and Pharmacology 70 (3), 629-640, 2014 | 226 | 2014 |
| The CompTox Chemistry Dashboard: a community data resource for environmental chemistry AJ Williams, CM Grulke, J Edwards, AD McEachran, K Mansouri, ... Journal of cheminformatics 9 (1), 61, 2017 | 215 | 2017 |
| A roadmap for the development of alternative (non-animal) methods for systemic toxicity testing D Basketter, H Clewell, I Kimber, A Rossi, B Blaauboer, R Burrier, ... | 198 | 2012 |
| Skin sensitization: reaction mechanistic applicability domains for structure− activity relationships AO Aptula, G Patlewicz, DW Roberts Chemical Research in Toxicology 18 (9), 1420-1426, 2005 | 175 | 2005 |
| Electrophilic chemistry related to skin sensitization. Reaction mechanistic applicability domain classification for a published data set of 106 chemicals tested in the mouse … DW Roberts, AO Aptula, G Patlewicz Chemical Research in Toxicology 20 (1), 44-60, 2007 | 137 | 2007 |
| Ranking of hair dye substances according to predicted sensitization potency: quantitative structure–activity relationships H Søsted, DA Basketter, E Estrada, JD Johansen, GY Patlewicz Contact Dermatitis 51 (5‐6), 241-254, 2004 | 137 | 2004 |
| The role of the European Chemicals Bureau in promoting the regulatory use of (Q) SAR methods AP Worth, A Bassan, J De Bruijn, A Gallegos Saliner, T Netzeva, M Pavan, ... SAR and QSAR in Environmental Research 18 (1-2), 111-125, 2007 | 135 | 2007 |
| A chemical dataset for evaluation of alternative approaches to skin‐sensitization testing GF Gerberick, CA Ryan, PS Kern, RJ Dearman, I Kimber, GY Patlewicz, ... Contact dermatitis 50 (5), 274-288, 2004 | 129 | 2004 |
| Mechanistic applicability domains for non-animal based prediction of toxicological endpoints. QSAR analysis of the Schiff base applicability domain for skin sensitization DW Roberts, AO Aptula, G Patlewicz Chemical research in toxicology 19 (9), 1228-1233, 2006 | 117 | 2006 |
| Non-enzymatic glutathione reactivity and in vitro toxicity: a non-animal approach to skin sensitization AO Aptula, G Patlewicz, DW Roberts, TW Schultz Toxicology in Vitro 20 (2), 239-247, 2006 | 111 | 2006 |
| T4 report: Toward good read-across practice (GRAP) guidance N Ball, MTD Cronin, J Shen, K Blackburn, ED Booth, M Bouhifd, E Donley, ... Altex 33 (2), 149, 2016 | 110 | 2016 |
| Skin‐sensitization structure‐activity relationships for aldehydes G Patlewicz, DA Basketter, CK Smith, SAM Hotchkiss, DW Roberts Contact Dermatitis 44 (6), 331-336, 2001 | 108 | 2001 |
| Use of category approaches, read-across and (Q) SAR: general considerations G Patlewicz, N Ball, ED Booth, E Hulzebos, E Zvinavashe, C Hennes Regulatory Toxicology and Pharmacology 67 (1), 1-12, 2013 | 98 | 2013 |
| TIMES-SS—a promising tool for the assessment of skin sensitization hazard. A characterization with respect to the OECD validation principles for (Q) SARs and an external … G Patlewicz, SD Dimitrov, LK Low, PS Kern, GD Dimitrova, MIH Comber, ... Regulatory Toxicology and Pharmacology 48 (2), 225-239, 2007 | 96 | 2007 |
