| PDSM, a motif for phosphorylation-dependent SUMO modification V Hietakangas, J Anckar, HA Blomster, M Fujimoto, JJ Palvimo, A Nakai, ... Proceedings of the National Academy of Sciences 103 (1), 45-50, 2006 | 627 | 2006 |
| Phosphorylation of serine 230 promotes inducible transcriptional activity of heat shock factor 1 CI Holmberg, V Hietakangas, A Mikhailov, JO Rantanen, M Kallio, ... The EMBO journal, 2001 | 426 | 2001 |
| Phosphorylation of serine 303 is a prerequisite for the stress-inducible SUMO modification of heat shock factor 1 V Hietakangas, JK Ahlskog, AM Jakobsson, M Hellesuo, NM Sahlberg, ... Molecular and cellular biology 23 (8), 2953-2968, 2003 | 417 | 2003 |
| Regulation of tissue growth through nutrient sensing V Hietakangas, SM Cohen Annual review of genetics 43, 389-410, 2009 | 327 | 2009 |
| Nutritional control of protein biosynthetic capacity by insulin via Myc in Drosophila AA Teleman, V Hietakangas, AC Sayadian, SM Cohen Cell metabolism 7 (1), 21-32, 2008 | 287 | 2008 |
| Rapid turnover of c-FLIPshort is determined by its unique C-terminal tail M Poukkula, A Kaunisto, V Hietakangas, K Denessiouk, T Katajamäki, ... Journal of Biological Chemistry 280 (29), 27345-27355, 2005 | 186 | 2005 |
| Regulation of Carbohydrate Energy Metabolism in Drosophila melanogaster J Mattila, V Hietakangas Genetics 207 (4), 1231-1253, 2017 | 182 | 2017 |
| Functional, metabolic and transcriptional maturation of human pancreatic islets derived from stem cells D Balboa, T Barsby, V Lithovius, J Saarimäki-Vire, M Omar-Hmeadi, ... Nature biotechnology 40 (7), 1042-1055, 2022 | 179 | 2022 |
| MAPK/ERK Signaling Regulates Insulin Sensitivity to Control Glucose Metabolism in Drosophila W Zhang, BJ Thompson, V Hietakangas, SM Cohen PLoS genetics 7 (12), e1002429, 2011 | 168 | 2011 |
| Re-evaluating AKT regulation: role of TOR complex 2 in tissue growth V Hietakangas, SM Cohen Genes & development 21 (6), 632-637, 2007 | 166 | 2007 |
| ER stress potentiates insulin resistance through PERK-mediated FOXO phosphorylation W Zhang, V Hietakangas, S Wee, SC Lim, J Gunaratne, SM Cohen Genes & development 27 (4), 441-449, 2013 | 146 | 2013 |
| NOTUM from Apc-mutant cells biases clonal competition to initiate cancer DJ Flanagan, N Pentinmikko, K Luopajärvi, NJ Willis, K Gilroy, AP Raven, ... Nature 594 (7863), 430-435, 2021 | 144 | 2021 |
| Inhibition of DNA binding by differential sumoylation of heat shock factors J Anckar, V Hietakangas, K Denessiouk, DJ Thiele, MS Johnson, ... Molecular and cellular biology, 2006 | 138 | 2006 |
| Formation of nuclear stress granules involves HSF2 and coincides with the nucleolar localization of Hsp70 TP Alastalo, M Hellesuo, A Sandqvist, V Hietakangas, M Kallio, ... Journal of cell science 116 (17), 3557-3570, 2003 | 138 | 2003 |
| Erythroid differentiation sensitizes K562 leukemia cells to TRAIL-induced apoptosis by downregulation of c-FLIP V Hietakangas, M Poukkula, KM Heiskanen, JT Karvinen, L Sistonen, ... Molecular and Cellular Biology 23 (4), 1278-1291, 2003 | 130 | 2003 |
| Glucose sensing by ChREBP/MondoA–Mlx transcription factors E Havula, V Hietakangas Seminars in cell & developmental biology 23 (6), 640-647, 2012 | 115 | 2012 |
| Mondo/ChREBP-Mlx-Regulated Transcriptional Network Is Essential for Dietary Sugar Tolerance in Drosophila E Havula, M Teesalu, T Hyötyläinen, H Seppälä, K Hasygar, P Auvinen, ... PLoS genetics 9 (4), e1003438, 2013 | 110 | 2013 |
| Novel proteomics strategy brings insight into the prevalence of SUMO-2 target sites HA Blomster, V Hietakangas, J Wu, P Kouvonen, S Hautaniemi, ... Molecular & cellular proteomics 8 (6), 1382-1390, 2009 | 106 | 2009 |
| Mondo-Mlx mediates organismal sugar sensing through the Gli-similar transcription factor sugarbabe J Mattila, E Havula, E Suominen, M Teesalu, I Surakka, R Hynynen, ... Cell reports 13 (2), 350-364, 2015 | 86 | 2015 |
| TOR complex 2 is needed for cell cycle progression and anchorage-independent growth of MCF7 and PC3 tumor cells V Hietakangas, SM Cohen BMC cancer 8, 1-8, 2008 | 85 | 2008 |
