| Icaritin exacerbates mitophagy and synergizes with doxorubicin to induce immunogenic cell death in hepatocellular carcinoma Z Yu, J Guo, M Hu, Y Gao, L Huang Acs Nano 14 (4), 4816-4828, 2020 | 221 | 2020 |
| Trapping of lipopolysaccharide to promote immunotherapy against colorectal cancer and attenuate liver metastasis W Song, K Tiruthani, Y Wang, L Shen, M Hu, O Dorosheva, K Qiu, ... Advanced materials 30 (52), 1805007, 2018 | 141 | 2018 |
| Nano-puerarin regulates tumor microenvironment and facilitates chemo-and immunotherapy in murine triple negative breast cancer model H Xu, M Hu, M Liu, S An, K Guan, M Wang, L Li, J Zhang, J Li, L Huang Biomaterials 235, 119769, 2020 | 103 | 2020 |
| Relaxin gene delivery mitigates liver metastasis and synergizes with check point therapy M Hu, Y Wang, L Xu, S An, Y Tang, X Zhou, J Li, R Liu, L Huang Nature communications 10 (1), 2993, 2019 | 100 | 2019 |
| mRNA delivery of a bispecific single‐domain antibody to polarize tumor‐associated macrophages and synergize immunotherapy against liver malignancies Y Wang, K Tiruthani, S Li, M Hu, G Zhong, Y Tang, S Roy, L Zhang, J Tan, ... Advanced Materials 33 (23), 2007603, 2021 | 82 | 2021 |
| An inflammatory-CCRK circuitry drives mTORC1-dependent metabolic and immunosuppressive reprogramming in obesity-associated hepatocellular carcinoma H Sun, W Yang, Y Tian, X Zeng, J Zhou, MTS Mok, W Tang, Y Feng, L Xu, ... Nature communications 9 (1), 5214, 2018 | 81 | 2018 |
| Hepatic macrophages act as a central hub for relaxin-mediated alleviation of liver fibrosis M Hu, Y Wang, Z Liu, Z Yu, K Guan, M Liu, M Wang, J Tan, L Huang Nature nanotechnology 16 (4), 466-477, 2021 | 79 | 2021 |
| Vasodilator hydralazine promotes nanoparticle penetration in advanced desmoplastic tumors Y Chen, W Song, L Shen, N Qiu, M Hu, Y Liu, Q Liu, L Huang ACS nano 13 (2), 1751-1763, 2019 | 69 | 2019 |
| Liver specific gene immunotherapies resolve immune suppressive ectopic lymphoid structures of liver metastases and prolong survival TJ Goodwin, L Shen, M Hu, J Li, R Feng, O Dorosheva, R Liu, L Huang Biomaterials 141, 260-271, 2017 | 52 | 2017 |
| Celastrol nanoemulsion induces immunogenicity and downregulates PD-L1 to boost abscopal effect in melanoma therapy N Qiu, Y Liu, Q Liu, Y Chen, L Shen, M Hu, X Zhou, Y Shen, J Gao, ... Biomaterials 269, 120604, 2021 | 49 | 2021 |
| Polymersomes via self-assembly of amphiphilic β-cyclodextrin-centered triarm star polymers for enhanced oral bioavailability of water-soluble chemotherapeutics M Hu, Y Shen, L Zhang, L Qiu Biomacromolecules 17 (3), 1026-1039, 2016 | 42 | 2016 |
| Tumour extracellular vesicles and particles induce liver metabolic dysfunction G Wang, J Li, L Bojmar, H Chen, Z Li, GC Tobias, M Hu, EA Homan, ... Nature 618 (7964), 374-382, 2023 | 41 | 2023 |
| Co-encapsulation of combretastatin-A4 phosphate and doxorubicin in polymersomes for synergistic therapy of nasopharyngeal epidermal carcinoma J Zhu, X Xu, M Hu, L Qiu Journal of biomedical nanotechnology 11 (6), 997-1006, 2015 | 36 | 2015 |
| Nanoparticle‐mediated HMGA1 silencing promotes lymphocyte infiltration and boosts checkpoint blockade immunotherapy for cancer Y Wang, W Song, M Hu, S An, L Xu, J Li, KA Kinghorn, R Liu, L Huang Advanced Functional Materials 28 (36), 1802847, 2018 | 35 | 2018 |
| Nanoparticle delivery of miR-122 inhibits colorectal cancer liver metastasis H Sendi, M Yazdimamaghani, M Hu, N Sultanpuram, J Wang, AS Moody, ... Cancer research 82 (1), 105-113, 2022 | 32 | 2022 |
| Strategies targeting tumor immune and stromal microenvironment and their clinical relevance M Hu, L Huang Advanced Drug Delivery Reviews 183, 114137, 2022 | 30 | 2022 |
| Locally Trapping the C‐C Chemokine Receptor Type 7 by Gene Delivery Nanoparticle Inhibits Lymphatic Metastasis Prior to Tumor Resection S An, K Tiruthani, Y Wang, L Xu, M Hu, J Li, W Song, H Jiang, J Sun, R Liu, ... Small 15 (9), 1805182, 2019 | 27 | 2019 |
| Relaxin gene delivery modulates macrophages to resolve cancer fibrosis and synergizes with immune checkpoint blockade therapy X Zhou, Y Liu, M Hu, M Wang, X Liu, L Huang Science Advances 7 (8), eabb6596, 2021 | 24 | 2021 |
| Polymer micelle-based combination therapy of paclitaxel and resveratrol with enhanced and selective antitumor activity M Hu, J Zhu, L Qiu RSC advances 4 (109), 64151-64161, 2014 | 22 | 2014 |
| Relaxin-FOLFOX-IL-12 triple combination therapy engages memory response and achieves long-term survival in colorectal cancer liver metastasis M Hu, X Zhou, Y Wang, K Guan, L Huang Journal of controlled release 319, 213-221, 2020 | 19 | 2020 |
Leaf HuangProfessor Emeritus, University of North Carolina at Chapel HillVerified email at email.unc.edu
