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Tim Lohoff
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Multi-omics profiling of mouse gastrulation at single-cell resolution
R Argelaguet, SJ Clark, H Mohammed, LC Stapel, C Krueger, ...
Nature 576 (7787), 487-491, 2019
3522019
Integration of spatial and single-cell transcriptomic data elucidates mouse organogenesis
T Lohoff, S Ghazanfar, A Missarova, N Koulena, N Pierson, JA Griffiths, ...
Nature biotechnology 40 (1), 74-85, 2022
1672022
Complementary activity of ETV5, RBPJ, and TCF3 drives formative transition from naive pluripotency
T Kalkan, S Bornelöv, C Mulas, E Diamanti, T Lohoff, M Ralser, ...
Cell stem cell 24 (5), 785-801. e7, 2019
872019
The circadian clock modulates global daily cycles of mRNA ribosome loading
A Missra, B Ernest, T Lohoff, Q Jia, J Satterlee, K Ke, AG von Arnim
The Plant Cell 27 (9), 2582-2599, 2015
812015
Inactivation of cancer mutations utilizing CRISPR/Cas9
C Gebler, T Lohoff, M Paszkowski-Rogacz, J Mircetic, D Chakraborty, ...
Journal of the National Cancer Institute 109 (1), djw183, 2017
482017
Distinct molecular trajectories converge to induce naive pluripotency
HT Stuart, GG Stirparo, T Lohoff, LE Bates, M Kinoshita, CY Lim, EJ Sousa, ...
Cell Stem Cell 25 (3), 388-406. e8, 2019
352019
Metabolic control of DNA methylation in naive pluripotent cells
RM Betto, L Diamante, V Perrera, M Audano, S Rapelli, A Lauria, ...
Nature genetics 53 (2), 215-229, 2021
322021
Decoding gene regulation in the mouse embryo using single-cell multi-omics
R Argelaguet, T Lohoff, JG Li, A Nakhuda, D Drage, F Krueger, L Velten, ...
BioRxiv, 2022.06. 15.496239, 2022
252022
Highly multiplexed spatially resolved gene expression profiling of mouse organogenesis
T Lohoff, S Ghazanfar, A Missarova, N Koulena, N Pierson, JA Griffiths, ...
BioRxiv, 2020.11. 20.391896, 2020
232020
Single-cell multi-omics profiling links dynamic DNA methylation to cell fate decisions during mouse early organogenesis
SJ Clark, R Argelaguet, T Lohoff, F Krueger, D Drage, B Göttgens, ...
Genome biology 23 (1), 202, 2022
142022
Inference of emergent spatio-temporal processes from single-cell sequencing reveals feedback between de novo DNA methylation and chromatin condensates
F Olmeda, T Lohoff, SJ Clark, L Benson, F Krüger, W Reik, S Rulands
bioRxiv, 2020.12. 30.424823, 2021
32021
Dynamic DNA methylation turnover at the exit of pluripotency epigenetically primes gene regulatory elements for hematopoietic lineage specification
A Parry, C Krueger, T Lohoff, S Wingett, S Schoenfelder, W Reik
bioRxiv, 2023.01. 11.523441, 2023
12023
Supervised spatial inference of dissociated single-cell data with SageNet
E Heidari, T Lohoff, RCV Tyser, JC Marioni, MD Robinson, S Ghazanfar
bioRxiv, 2022.04. 14.488419, 2022
12022
Investing in vision: Innovation in retinal therapeutics and the influence on venture capital investment
D Hristodorov, T Lohoff, N Luneborg, GJ Mulder, SJ Clark
Progress in Retinal and Eye Research, 101243, 2024
2024
3078–EOMESODERMIN IS A PIVOTAL REGULATOR OF YOLK SAC BLOOD AND ENDOTHELIAL DEVELOPMENT
L Harland, B Theeuwes, A Bisia, ML Ton, R Argelaguet, S Clark, T Lohoff, ...
Experimental Hematology 124, S89, 2023
2023
Multi-omics characterisation of mouse gastrulation and organogenesis at single-cell resolution
T Lohoff
2021
Inference of emergent spatio-temporal processes in single-cell genomics
F Olmeda, T Lohoff, S Clark, L Benson, F Krueger, W Reik, S Rulands
APS March Meeting Abstracts 2021, S13. 009, 2021
2021
Setting the epigenetic stage for differentiation: a collective phenomenon
F Olmeda, S Clark, T Lohoff, H Lee, W Reik, S Rulands
APS March Meeting Abstracts 2019, Y51. 004, 2019
2019
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Articles 1–18