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Nicole M Martinez
Nicole M Martinez
Verified email at yale.edu
Title
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Cited by
Year
Convergence of Acquired Mutations and Alternative Splicing of CD19 Enables Resistance to CART-19 ImmunotherapyAlternative Splicing of CD19 Enables Resistance to CART-19
E Sotillo, DM Barrett, KL Black, A Bagashev, D Oldridge, G Wu, ...
Cancer discovery 5 (12), 1282-1295, 2015
9252015
Control of alternative splicing in immune responses: many regulators, many predictions, much still to learn
NM Martinez, KW Lynch
Immunological reviews 253 (1), 216-236, 2013
1632013
Alternative splicing networks regulated by signaling in human T cells
NM Martinez, Q Pan, BS Cole, CA Yarosh, GA Babcock, F Heyd, W Zhu, ...
Rna 18 (5), 1029-1040, 2012
952012
mRNA structure determines modification by pseudouridine synthase 1
TM Carlile, NM Martinez, C Schaening, A Su, TA Bell, B Zinshteyn, ...
Nature chemical biology 15 (10), 966-974, 2019
672019
Widespread JNK-dependent alternative splicing induces a positive feedback loop through CELF2-mediated regulation of MKK7 during T-cell activation
NM Martinez, L Agosto, J Qiu, MJ Mallory, MR Gazzara, Y Barash, X Fu, ...
Genes & development 29 (19), 2054-2066, 2015
632015
Induced transcription and stability of CELF2 mRNA drives widespread alternative splicing during T-cell signaling
MJ Mallory, SJ Allon, J Qiu, MR Gazzara, I Tapescu, NM Martinez, XD Fu, ...
Proceedings of the National Academy of Sciences 112 (17), E2139-E2148, 2015
552015
Position-dependent activity of CELF2 in the regulation of splicing and implications for signal-responsive regulation in T cells
S Ajith, MR Gazzara, BS Cole, G Shankarling, NM Martinez, MJ Mallory, ...
RNA biology 13 (6), 569-581, 2016
332016
Regulation and function of RNA pseudouridylation in human cells
EK Borchardt, NM Martinez, WV Gilbert
Annual review of genetics 54, 309-336, 2020
322020
Inhibition of zinc-dependent histone deacetylases with a chemically triggered electrophile
ZV Boskovic, MM Kemp, AM Freedy, VS Viswanathan, MS Pop, JH Fuller, ...
ACS Chemical Biology 11 (7), 1844-1851, 2016
232016
Pre-mRNA modifications and their role in nuclear processing
NM Martinez, WV Gilbert
Quantitative Biology 6 (3), 210-227, 2018
202018
A novel HDAC inhibitor with a hydroxy-pyrimidine scaffold
MM Kemp, Q Wang, JH Fuller, N West, NM Martinez, EM Morse, ...
Bioorganic & medicinal chemistry letters 21 (14), 4164-4169, 2011
202011
Convergence of Acquired Mutations and Alternative Splicing of CD19 Enables Resistance to CART-19 Immunotherapy. Cancer Discov 5, 1282–1295, doi: 10.1158/2159-8290
E Sotillo, DM Barrett, KL Black, A Bagashev, D Oldridge, G Wu, ...
CD-15-1020, 2015
162015
Pseudouridine synthases modify human pre-mRNA co-transcriptionally and affect pre-mRNA processing
NM Martinez, A Su, MC Burns, JK Nussbacher, C Schaening, S Sathe, ...
Molecular Cell 82 (3), 645-659. e9, 2022
15*2022
Alternative splicing of CD19 mRNA in leukemias escaping CART-19 immunotherapy eliminates the cognate epitope and contributes to treatment failure
E Sotillo, D Barrett, A Bagashev, K Black, C Lanauze, D Oldridge, ...
Cancer Research 75 (15_Supplement), 3143-3143, 2015
32015
Pseudouridine site assignment by high-throughput in vitro RNA pseudouridylation and sequencing
NM Martinez, C Schaening-Burgos, WV Gilbert
Methods in Enzymology 658, 277-310, 2021
22021
Investigating pseudouridylation mechanisms by high-throughput in vitro RNA pseudouridylation and sequencing
NM Martinez, WV Gilbert
RNA Modifications, 379-397, 2021
22021
Regulation of CD19 Exon 2 inclusion in B-lymphoid cells by splicing factors and epigenetic marks
K Black, E Sotillo, N Martinez, M Gazzara, A Barrera, Y Barash, K Lynch, ...
Blood 126 (23), 2425, 2015
22015
Interplay between signaling and splicing during T cell activation: A study on MKK7
NM Martinez
University of Pennsylvania, 2015
2015
Convergence of Acquired Mutations and Alternative Splicing of CD19 Enables Resistance to CART-19 Immunotherapy
JM Lynch, SA Grupp, A Thomas-Tikhonenko, AB Black, G Wu, C Lanauze, ...
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