Detection and localization of surgically resectable cancers with a multi-analyte blood test JD Cohen, L Li, Y Wang, C Thoburn, B Afsari, L Danilova, C Douville, ... Science 359 (6378), 926-930, 2018 | 2515 | 2018 |
Variation in cancer risk among tissues can be explained by the number of stem cell divisions C Tomasetti, B Vogelstein Science 347 (6217), 78-81, 2015 | 2283 | 2015 |
Circulating tumor DNA analysis detects minimal residual disease and predicts recurrence in patients with stage II colon cancer J Tie, Y Wang, C Tomasetti, L Li, S Springer, I Kinde, N Silliman, M Tacey, ... Science translational medicine 8 (346), 346ra92-346ra92, 2016 | 1430 | 2016 |
Stem cell divisions, somatic mutations, cancer etiology, and cancer prevention C Tomasetti, L Li, B Vogelstein Science 355 (6331), 1330-1334, 2017 | 1238 | 2017 |
Cancer-associated mutations in endometriosis without cancer MS Anglesio, N Papadopoulos, A Ayhan, TM Nazeran, M Noë, ... New England Journal of Medicine 376 (19), 1835-1848, 2017 | 613 | 2017 |
Combined circulating tumor DNA and protein biomarker-based liquid biopsy for the earlier detection of pancreatic cancers JD Cohen, AA Javed, C Thoburn, F Wong, J Tie, P Gibbs, CM Schmidt, ... Proceedings of the National Academy of Sciences 114 (38), 10202-10207, 2017 | 558 | 2017 |
Circulating tumor DNA analysis guiding adjuvant therapy in stage II colon cancer J Tie, JD Cohen, K Lahouel, SN Lo, Y Wang, S Kosmider, R Wong, ... New England Journal of Medicine 386 (24), 2261-2272, 2022 | 546 | 2022 |
Circulating tumor DNA analyses as markers of recurrence risk and benefit of adjuvant therapy for stage III colon cancer J Tie, JD Cohen, Y Wang, M Christie, K Simons, M Lee, R Wong, ... JAMA oncology 5 (12), 1710-1717, 2019 | 520 | 2019 |
Feasibility of blood testing combined with PET-CT to screen for cancer and guide intervention AM Lennon, AH Buchanan, I Kinde, A Warren, A Honushefsky, AT Cohain, ... Science 369 (6499), eabb9601, 2020 | 502 | 2020 |
Half or more of the somatic mutations in cancers of self-renewing tissues originate prior to tumor initiation C Tomasetti, B Vogelstein, G Parmigiani Proceedings of the National Academy of Sciences 110 (6), 1999-2004, 2013 | 471 | 2013 |
Only three driver gene mutations are required for the development of lung and colorectal cancers C Tomasetti, L Marchionni, MA Nowak, G Parmigiani, B Vogelstein Proceedings of the National Academy of Sciences 112 (1), 118-123, 2015 | 453 | 2015 |
Serial circulating tumour DNA analysis during multimodality treatment of locally advanced rectal cancer: a prospective biomarker study J Tie, JD Cohen, Y Wang, L Li, M Christie, K Simons, H Elsaleh, ... Gut 68 (4), 663-671, 2019 | 313 | 2019 |
Genome-wide quantification of rare somatic mutations in normal human tissues using massively parallel sequencing ML Hoang, I Kinde, C Tomasetti, KW McMahon, TA Rosenquist, ... Proceedings of the National Academy of Sciences 113 (35), 9846-9851, 2016 | 228 | 2016 |
Evaluation of liquid from the Papanicolaou test and other liquid biopsies for the detection of endometrial and ovarian cancers Y Wang, L Li, C Douville, JD Cohen, TT Yen, I Kinde, K Sundfelt, SK Kjær, ... Science translational medicine 10 (433), eaap8793, 2018 | 223 | 2018 |
Prognostic potential of circulating tumor DNA measurement in postoperative surveillance of nonmetastatic colorectal cancer Y Wang, L Li, JD Cohen, I Kinde, J Ptak, M Popoli, J Schaefer, N Silliman, ... JAMA oncology 5 (8), 1118-1123, 2019 | 196 | 2019 |
Circulating tumor DNA as a potential marker of adjuvant chemotherapy benefit following surgery for localized pancreatic cancer B Lee, L Lipton, J Cohen, J Tie, AA Javed, L Li, D Goldstein, M Burge, ... Annals of Oncology 30 (9), 1472-1478, 2019 | 177 | 2019 |
Non-invasive detection of urothelial cancer through the analysis of driver gene mutations and aneuploidy SU Springer, CH Chen, MDC Rodriguez Pena, L Li, C Douville, Y Wang, ... Elife 7, e32143, 2018 | 165 | 2018 |
A multimodality test to guide the management of patients with a pancreatic cyst S Springer, DL Masica, M Dal Molin, C Douville, CJ Thoburn, B Afsari, L Li, ... Science translational medicine 11 (501), eaav4772, 2019 | 149 | 2019 |
Circulating tumor DNA dynamics and recurrence risk in patients undergoing curative intent resection of colorectal cancer liver metastases: A prospective cohort study J Tie, Y Wang, J Cohen, L Li, W Hong, M Christie, HL Wong, S Kosmider, ... PLoS medicine 18 (5), e1003620, 2021 | 134 | 2021 |
Role of symmetric and asymmetric division of stem cells in developing drug resistance C Tomasetti, D Levy Proceedings of the National Academy of Sciences 107 (39), 16766-16771, 2010 | 133 | 2010 |