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Adele Pauley
Adele Pauley
Research scientist, Monsanto
Verified email at monsanto.com
Title
Cited by
Cited by
Year
Membrane-anchored aspartyl protease with Alzheimer's disease β-secretase activity
R Yan, MJ Bienkowski, ME Shuck, H Miao, MC Tory, AM Pauley, ...
Nature 402 (6761), 533-537, 1999
20471999
The Notch intracellular domain is ubiquitinated and negatively regulated by the mammalian Sel-10 homolog
C Öberg, J Li, A Pauley, E Wolf, M Gurney, U Lendahl
Journal of Biological Chemistry 276 (38), 35847-35853, 2001
5302001
SEL-10 is an inhibitor of notch signaling that targets notch for ubiquitin-mediated protein degradation
G Wu, S Lyapina, I Das, J Li, M Gurney, A Pauley, I Chui, RJ Deshaies, ...
Molecular and cellular biology, 2001
4432001
Distinction of microsomal prostaglandin E synthase-1 (mPGES-1) inhibition from cyclooxygenase-2 inhibition in cells using a novel, selective mPGES-1 inhibitor
G Mbalaviele, AM Pauley, AF Shaffer, BS Zweifel, S Mathialagan, ...
Biochemical pharmacology 79 (10), 1445-1454, 2010
892010
SEL‐10 interacts with presenilin 1, facilitates its ubiquitination, and alters A‐beta peptide production
J Li, AM Pauley, RL Myers, R Shuang, JR Brashler, R Yan, AE Buhl, ...
Journal of neurochemistry 82 (6), 1540-1548, 2002
892002
Direct interaction of soluble human recombinant tau protein with Aβ 1–42 results in tau aggregation and hyperphosphorylation by tau protein kinase II
KB Rank, AM Pauley, K Bhattacharya, Z Wang, DB Evans, TJ Fleck, ...
FEBS letters 514 (2-3), 263-268, 2002
812002
The Candida albicans myristoyl-CoA: protein N-myristoyltransferase gene. Isolation and expression in Saccharomyces cerevisiae and Escherichia coli.
RC Wiegand, C Carr, JC Minnerly, AM Pauley, CP Carron, CA Langner, ...
Journal of Biological Chemistry 267 (12), 8591-8598, 1992
781992
Positive and negative regulation of the γ-secretase activity by nicastrin in a murine model
J Li, GJ Fici, CA Mao, RL Myers, R Shuang, GP Donoho, AM Pauley, ...
Journal of Biological Chemistry 278 (35), 33445-33449, 2003
682003
Autoactivation of human ADAM8: a novel pre-processing step is required for catalytic activity
T Hall, JW Leone, JF Wiese, DW Griggs, LE Pegg, AM Pauley, ...
Bioscience reports 29 (4), 217-228, 2009
262009
Structure of human ADAM-8 catalytic domain complexed with batimastat
T Hall, HS Shieh, JE Day, N Caspers, JE Chrencik, JM Williams, LE Pegg, ...
Acta Crystallographica Section F: Structural Biology and Crystallization …, 2012
162012
ADAM8 substrate specificity: influence of pH on pre-processing and proteoglycan degradation
T Hall, LE Pegg, AM Pauley, HD Fischer, AG Tomasselli, MD Zack
Archives of biochemistry and biophysics 491 (1-2), 106-111, 2009
132009
Changes in γ-secretase activity and specificity caused by the introduction of consensus aspartyl protease active motif in Presenilin 1
DB Carter, E Dunn, AM Pauley, DD McKinley, TJ Fleck, BR Ellerbrook, ...
Molecular Neurodegeneration 3, 1-12, 2008
132008
Human sel-10 polypeptides and polynucleotides that encode them
ME Gurney, AM Pauley, J Li
US Patent 6,730,778, 2004
12004
Human sel-10 polypeptides and polynucleotides that encode them
ME Gurney, AM Pauley, J Li
US Patent 6,638,731, 2003
12003
Presenilin enhancers Pen-1 and Pen-2 and their roles in a-beta production
JH Li, R Myers, RQ Shuang, D Carter, D McKinley, R Hiebsch, ...
NEUROBIOLOGY OF AGING 23 (1), S206-S206, 2002
12002
Human sel-10 polypeptides and polynucleotides that encode them
M Gurney, A Pauley, J Li
US Patent App. 10/653,676, 2005
2005
Human sel-10 polypeptides and polynucleotides that encode them
M Gurney, A Pauley, J Li
US Patent App. 10/653,496, 2004
2004
Human sel-10 polypeptides and polynucleotides that encode them
M Gurney, A Pauley, J Li
US Patent App. 10/653,517, 2004
2004
Human sel-10 polypeptides and polynucleotides that encode them
M Gurney, A Pauley, J Li
US Patent App. 10/653,497, 2004
2004
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