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Pablo Machado
Pablo Machado
Professor da Escola de Ciências da Saúde e da Vida, Pontifícia Universidade Católica do Rio Grande
Verified email at pucrs.br
Title
Cited by
Cited by
Year
Solvent-free heterocyclic synthesis
MAP Martins, CP Frizzo, DN Moreira, L Buriol, P Machado
Chemical reviews 109 (9), 4140-4182, 2009
7192009
Antinociceptive effect of novel trihalomethyl-substituted pyrazoline methyl esters in formalin and hot-plate tests in mice
J Milano, SM Oliveira, MF Rossato, PD Sauzem, P Machado, P Beck, ...
European Journal of pharmacology 581 (1-2), 86-96, 2008
1212008
Cyclooxygenase-2/PGE2 pathway facilitates pentylenetetrazol-induced seizures
MS Oliveira, AF Furian, LFF Royes, MR Fighera, NG Fiorenza, M Castelli, ...
Epilepsy research 79 (1), 14-21, 2008
1202008
Design and microwave-assisted synthesis of 5-trifluoromethyl-4, 5-dihydro-1H-pyrazoles: novel agents with analgesic and anti-inflammatory properties
PD Sauzem, P Machado, MA Rubin, GS Sant'Anna, HB Faber, ...
European journal of medicinal chemistry 43 (6), 1237-1247, 2008
1192008
Synthesis, antimicrobial activity, and QSAR studies of furan-3-carboxamides
N Zanatta, SH Alves, HS Coelho, DM Borchhardt, P Machado, KM Flores, ...
Bioorganic & medicinal chemistry 15 (5), 1947-1958, 2007
892007
Ultrasound promoted synthesis of 5-hydroxy-5-trihalomethyl-4, 5-dihydroisoxazoles and β-enamino trihalomethyl ketones in water
MAP Martins, CMP Pereira, W Cunico, S Moura, FA Rosa, RL Peres, ...
Ultrasonics sonochemistry 13 (4), 364-370, 2006
822006
Straightforward and regiospecific synthesis of pyrazole-5-carboxylates from unsymmetrical enaminodiketones
FA Rosa, P Machado, PS Vargas, HG Bonacorso, N Zanatta, MAP Martins
Synlett 2008 (11), 1673-1678, 2008
802008
Microwave-assisted synthesis of 5-trichloromethyl substituted 1-phenyl-1H-pyrazoles and 1, 2-dimethylpyrazolium chlorides
MAP Martins, CMP Pereira, P Beck, P Machado, S Moura, MVM Teixeira, ...
Tetrahedron letters 44 (35), 6669-6672, 2003
752003
Ultrasound promoted synthesis of 2-imidazolines in water: a greener approach toward monoamine oxidase inhibitors
GS Sant’Anna, P Machado, PD Sauzem, FA Rosa, MA Rubin, J Ferreira, ...
Bioorganic & Medicinal Chemistry Letters 19 (2), 546-549, 2009
622009
Effect of 5-trifluoromethyl-4, 5-dihydro-1H-pyrazoles on chronic inflammatory pain model in rats
PD Sauzem, GS Sant'Anna, P Machado, MMMF Duarte, J Ferreira, ...
European journal of pharmacology 616 (1-3), 91-100, 2009
602009
Antipyretic and antioxidant activities of 5-trifluoromethyl-4, 5-dihydro-1H-pyrazoles in rats
JSM Pasin, APO Ferreira, ALL Saraiva, V Ratzlaff, R Andrighetto, ...
Brazilian Journal of Medical and Biological Research 43, 1193-1202, 2010
562010
2-(Quinolin-4-yloxy)acetamides Are Active against Drug-Susceptible and Drug-Resistant Mycobacterium tuberculosis Strains
K Pissinate, AD Villela, V Rodrigues-Junior, BC Giacobbo, ES Grams, ...
ACS medicinal chemistry letters 7 (3), 235-239, 2016
542016
Reaction of β‐dimethylaminovinyl ketones with hydroxylamine: A simple and useful method for synthesis of 3‐and 5‐substituted isoxazoles
FA Rosa, P Machado, HG Bonacorso, N Zanatta, MAP Martins
Journal of Heterocyclic Chemistry 45 (3), 879-885, 2008
512008
New insights into the SAR and drug combination synergy of 2-(quinolin-4-yloxy) acetamides against Mycobacterium tuberculosis
BC Giacobbo, K Pissinate, V Rodrigues-Junior, AD Villela, ES Grams, ...
European Journal of Medicinal Chemistry 126, 491-501, 2017
482017
Antinociceptive action of 4-methyl-5-trifluoromethyl-5-hydroxy-4, 5-dihydro-1H-pyrazole methyl ester in models of inflammatory pain in mice
J Milano, MF Rossato, SM Oliveira, C Drewes, P Machado, P Beck, ...
Life sciences 83 (21-22), 739-746, 2008
452008
Mycobacterium tuberculosis Shikimate Pathway Enzymes as Targets for the Rational Design of Anti-Tuberculosis Drugs
JES Nunes, MA Duque, TF de Freitas, L Galina, LFSM Timmers, ...
Molecules 25 (6), 1259, 2020
442020
Short-chain fatty acid acetate triggers antiviral response mediated by RIG-I in cells from infants with respiratory syncytial virus bronchiolitis
KH Antunes, RT Stein, C Franceschina, EF da Silva, DN de Freitas, ...
EBioMedicine 77, 2022
432022
Efficient and highly regioselective synthesis of ethyl 1-(2, 4-dichlorophenyl)-1H-pyrazole-3-carboxylates under ultrasound irradiation
P Machado, GR Lima, M Rotta, HG Bonacorso, N Zanatta, MAP Martins
Ultrasonics sonochemistry 18 (1), 293-299, 2011
392011
Microwave-assisted synthesis of novel 5-trichloromethyl-4, 5-dihydro-1H-1-pyrazole methyl esters under solvent free conditions
MAP Martins, P Beck, P Machado, S Brondani, S Moura, N Zanatta, ...
Journal of the Brazilian Chemical Society 17, 408-411, 2006
392006
Design, synthesis, and evaluation of new 2-(quinoline-4-yloxy) acetamide-based antituberculosis agents
AF Borsoi, JD Paz, BL Abbadi, FS Macchi, N Sperotto, K Pissinate, ...
European Journal of Medicinal Chemistry 192, 112179, 2020
362020
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