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Riekelt Houtkooper
Riekelt Houtkooper
Professor of Translational Metabolism, Academic Medical Center (AMC), Amsterdam
Verified email at amc.nl
Title
Cited by
Cited by
Year
Sirtuins as regulators of metabolism and healthspan
RH Houtkooper, E Pirinen, J Auwerx
Nature reviews Molecular cell biology 13 (4), 225-238, 2012
20402012
Calorie restriction-like effects of 30 days of resveratrol supplementation on energy metabolism and metabolic profile in obese humans
S Timmers, E Konings, L Bilet, RH Houtkooper, T van de Weijer, ...
Cell metabolism 14 (5), 612-622, 2011
13972011
The NAD+ precursor nicotinamide riboside enhances oxidative metabolism and protects against high-fat diet-induced obesity
C Cantó, RH Houtkooper, E Pirinen, DY Youn, MH Oosterveer, Y Cen, ...
Cell metabolism 15 (6), 838-847, 2012
12002012
The NAD+/sirtuin pathway modulates longevity through activation of mitochondrial UPR and FOXO signaling
L Mouchiroud, RH Houtkooper, N Moullan, E Katsyuba, D Ryu, C Cantó, ...
Cell 154 (2), 430-441, 2013
11662013
Mitonuclear protein imbalance as a conserved longevity mechanism
RH Houtkooper, L Mouchiroud, D Ryu, N Moullan, E Katsyuba, G Knott, ...
Nature 497 (7450), 451-457, 2013
10142013
The Secret Life of NAD+: An Old Metabolite Controlling New Metabolic Signaling Pathways
RH Houtkooper, C Cantó, RJ Wanders, J Auwerx
Endocrine reviews 31 (2), 194-223, 2010
9812010
PARP-1 inhibition increases mitochondrial metabolism through SIRT1 activation
P Bai, C Cantó, H Oudart, A Brunyánszki, Y Cen, C Thomas, H Yamamoto, ...
Cell metabolism 13 (4), 461-468, 2011
8612011
The metabolic footprint of aging in mice
RH Houtkooper, C Argmann, SM Houten, C Cantó, EH Jeninga, ...
Scientific reports 1 (1), 134, 2011
5332011
Metabolic flexibility as an adaptation to energy resources and requirements in health and disease
RL Smith, MR Soeters, RCI Wüst, RH Houtkooper
Endocrine reviews 39 (4), 489-517, 2018
4962018
Cardiolipin, the heart of mitochondrial metabolism
RH Houtkooper, FM Vaz
Cellular and Molecular Life Sciences 65, 2493-2506, 2008
4942008
Tetracyclines disturb mitochondrial function across eukaryotic models: a call for caution in biomedical research
N Moullan, L Mouchiroud, X Wang, D Ryu, EG Williams, A Mottis, ...
Cell reports 10 (10), 1681-1691, 2015
4782015
Imp2 controls oxidative phosphorylation and is crucial for preserving glioblastoma cancer stem cells
M Janiszewska, ML Suvŕ, N Riggi, RH Houtkooper, J Auwerx, ...
Genes & development 26 (17), 1926-1944, 2012
4432012
Pharmacological approaches to restore mitochondrial function
PA Andreux, RH Houtkooper, J Auwerx
Nature reviews Drug discovery 12 (6), 465-483, 2013
3992013
Cardiolipin provides an essential activating platform for caspase-8 on mitochondria
F Gonzalvez, ZT Schug, RH Houtkooper, ED MacKenzie, DG Brooks, ...
The Journal of cell biology 183 (4), 681-696, 2008
3142008
Cardiac and skeletal muscle defects in a mouse model of human Barth syndrome
D Acehan, F Vaz, RH Houtkooper, J James, V Moore, C Tokunaga, ...
Journal of biological chemistry 286 (2), 899-908, 2011
2882011
Laminar shear stress inhibits endothelial cell metabolism via KLF2-mediated repression of PFKFB3
A Doddaballapur, KM Michalik, Y Manavski, T Lucas, RH Houtkooper, ...
Arteriosclerosis, thrombosis, and vascular biology 35 (1), 137-145, 2015
2822015
Microbial stimulation of different Toll-like receptor signalling pathways induces diverse metabolic programmes in human monocytes
E Lachmandas, L Boutens, JM Ratter, A Hijmans, GJ Hooiveld, ...
Nature microbiology 2 (3), 1-10, 2016
2672016
Disorders of mitochondrial long-chain fatty acid oxidation and the carnitine shuttle
SJG Knottnerus, JC Bleeker, RCI Wüst, S Ferdinandusse, L IJlst, ...
Reviews in Endocrine and Metabolic Disorders 19, 93-106, 2018
2642018
Mutations in LPIN1 cause recurrent acute myoglobinuria in childhood
A Zeharia, A Shaag, RH Houtkooper, T Hindi, P de Lonlay, G Erez, ...
The American Journal of Human Genetics 83 (4), 489-494, 2008
2582008
Metabolic networks of longevity
RH Houtkooper, RW Williams, J Auwerx
Cell 142 (1), 9-14, 2010
2442010
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