| A deep learning approach to antibiotic discovery JM Stokes, K Yang, K Swanson, W Jin, A Cubillos-Ruiz, NM Donghia, ... Cell 180 (4), 688-702. e13, 2020 | 1653 | 2020 |
| Pentamidine sensitizes Gram-negative pathogens to antibiotics and overcomes acquired colistin resistance JM Stokes, CR MacNair, B Ilyas, S French, JP Côté, C Bouwman, ... Nature microbiology 2 (5), 1-8, 2017 | 298 | 2017 |
| CARD 2023: expanded curation, support for machine learning, and resistome prediction at the Comprehensive Antibiotic Resistance Database BP Alcock, W Huynh, R Chalil, KW Smith, AR Raphenya, MA Wlodarski, ... Nucleic acids research 51 (D1), D690-D699, 2023 | 291 | 2023 |
| Bicarbonate alters bacterial susceptibility to antibiotics by targeting the proton motive force MA Farha, S French, J Stokes, ED Brown ACS infectious diseases, 2018 | 111 | 2018 |
| Assembly and clustering of natural antibiotics guides target identification CW Johnston, MA Skinnider, CA Dejong, PN Rees, GM Chen, CG Walker, ... Nature chemical biology 12 (4), 233-239, 2016 | 108 | 2016 |
| Antagonism screen for inhibitors of bacterial cell wall biogenesis uncovers an inhibitor of undecaprenyl diphosphate synthase MA Farha, TL Czarny, CL Myers, LJ Worrall, S French, DG Conrady, ... Proceedings of the National Academy of Sciences 112 (35), 11048-11053, 2015 | 106 | 2015 |
| Cold stress makes Escherichia coli susceptible to glycopeptide antibiotics by altering outer membrane integrity JM Stokes, S French, OG Ovchinnikova, C Bouwman, C Whitfield, ... Cell chemical biology 23 (2), 267-277, 2016 | 87 | 2016 |
| Elevated temperatures and carbon dioxide concentrations: effects on selected microbial activities in temperate agricultural soils S French, D Levy-Booth, A Samarajeewa, KE Shannon, J Smith, ... World Journal of Microbiology and Biotechnology 25, 1887-1900, 2009 | 80 | 2009 |
| Potentiation of antibiotics against Gram-negative bacteria by polymyxin B analogue SPR741 from unique perturbation of the outer membrane S French, M Farha, MJ Ellis, Z Sameer, JP Côté, N Cotroneo, T Lister, ... ACS infectious diseases 6 (6), 1405-1412, 2019 | 77 | 2019 |
| Structural and kinetic characterization of diazabicyclooctanes as dual inhibitors of both serine-β-lactamases and penicillin-binding proteins AM King, DT King, S French, E Brouillette, A Asli, JAN Alexander, ... ACS chemical biology 11 (4), 864-868, 2016 | 65 | 2016 |
| A robust platform for chemical genomics in bacterial systems S French, C Mangat, A Bharat, JP Côté, H Mori, ED Brown Molecular biology of the cell 27 (6), 1015-1025, 2016 | 65 | 2016 |
| A macrophage-based screen identifies antibacterial compounds selective for intracellular Salmonella Typhimurium MJ Ellis, CN Tsai, JW Johnson, S French, W Elhenawy, S Porwollik, ... Nature communications 10 (1), 197, 2019 | 59 | 2019 |
| The genome-wide interaction network of nutrient stress genes in Escherichia coli JP Côté, S French, SS Gehrke, CR MacNair, CS Mangat, A Bharat, ... MBio 7 (6), 10.1128/mbio. 01714-16, 2016 | 51 | 2016 |
| Discovery of Novel Cell Wall-Active Compounds Using PywaC, a Sensitive Reporter of Cell Wall Stress, in the Model Gram-Positive Bacterium Bacillus subtilis TL Czarny, AL Perri, S French, ED Brown Antimicrobial Agents and Chemotherapy 58 (6), 3261-3269, 2014 | 48 | 2014 |
| The dynamic nature of bacterial surfaces: Implications for metal-membrane interaction S French, D Puddephatt, M Habash, S Glasauer Critical Reviews in Microbiology 39 (2), 196-217, 2013 | 42 | 2013 |
| Identification of two phosphate starvation-induced wall teichoic acid hydrolases provides first insights into the degradative pathway of a key bacterial cell wall component CL Myers, FKK Li, BM Koo, OM El-Halfawy, S French, CA Gross, ... Journal of Biological Chemistry 291 (50), 26066-26082, 2016 | 39 | 2016 |
| Chemical screen for vancomycin antagonism uncovers probes of the gram-negative outer membrane K Klobucar, JP Côté, S French, L Borrillo, ABY Guo, MH Serrano-Wu, ... ACS Chemical Biology 16 (5), 929-942, 2021 | 38 | 2021 |
| Genetic and chemical screening in human blood serum reveals unique antibacterial targets and compounds against Klebsiella pneumoniae BS Weber, AM De Jong, ABY Guo, S Dharavath, S French, ... Cell Reports 32 (3), 2020 | 35 | 2020 |
| A multiplexable assay for screening antibiotic lethality against drug-tolerant bacteria JM Stokes, A Gutierrez, AJ Lopatkin, IW Andrews, S French, I Matic, ... Nature Methods 16 (4), 303-306, 2019 | 35 | 2019 |
| Gene dispensability in Escherichia coli grown in thirty different carbon environments M Tong, S French, SS El Zahed, WK Ong, PD Karp, ED Brown MBio 11 (5), 10.1128/mbio. 02259-20, 2020 | 31 | 2020 |
Eric D BrownProfessor of Biochemistry, McMaster UniversityVerified email at mcmaster.ca
