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R J Scott Lacombe
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Brain docosahexaenoic acid uptake and metabolism
RJS Lacombe, R Chouinard-Watkins, RP Bazinet
Molecular Aspects of Medicine 64, 109-134, 2018
1682018
Retroconversion is a minor contributor to increases in eicosapentaenoic acid following docosahexaenoic acid feeding as determined by compound specific isotope analysis in rat liver
AH Metherel, R Chouinard-Watkins, MO Trépanier, RJS Lacombe, ...
Nutrition & metabolism 14, 1-8, 2017
462017
Compound-specific isotope analysis resolves the dietary origin of docosahexaenoic acid in the mouse brain [S]
RJS Lacombe, V Giuliano, SM Colombo, MT Arts, RP Bazinet
Journal of Lipid Research 58 (10), 2071-2081, 2017
452017
DHA esterified to phosphatidylserine or phosphatidylcholine is more efficient at targeting the brain than DHA esterified to triacylglycerol
R Chouinard‐Watkins, RJS Lacombe, AH Metherel, M Masoodi, ...
Molecular nutrition & food research 63 (9), 1801224, 2019
342019
Mechanisms regulating brain docosahexaenoic acid uptake: what is the recent evidence?
R Chouinard-Watkins, RJS Lacombe, RP Bazinet
Current Opinion in Clinical Nutrition & Metabolic Care 21 (2), 71-77, 2018
242018
Complete assessment of whole-body n-3 and n-6 PUFA synthesis-secretion kinetics and DHA turnover in a rodent model
AH Metherel, RJS Lacombe, R Chouinard-Watkins, KE Hopperton, ...
Journal of lipid research 59 (2), 357-367, 2018
242018
Docosahexaenoic acid is both a product of and a precursor to tetracosahexaenoic acid in the rat [S]
AH Metherel, RJS Lacombe, R Chouinard-Watkins, RP Bazinet
Journal of Lipid Research 60 (2), 412-420, 2019
232019
Low linoleic acid foods with added DHA given to Malawian children with severe acute malnutrition improve cognition: a randomized, triple-blinded, controlled clinical trial
K Stephenson, M Callaghan-Gillespie, K Maleta, M Nkhoma, M George, ...
The American Journal of Clinical Nutrition 115 (5), 1322-1333, 2022
212022
Phospholipid class-specific brain enrichment in response to lysophosphatidylcholine docosahexaenoic acid infusion
R Chouinard-Watkins, CT Chen, AH Metherel, RJS Lacombe, F Thies, ...
Biochimica et Biophysica Acta (BBA)-Molecular and Cell Biology of Lipids …, 2017
212017
Maternal liver docosahexaenoic acid (DHA) stores are increased via higher serum unesterified DHA uptake in pregnant long Evans rats
AH Metherel, AP Kitson, AF Domenichiello, RJS Lacombe, KE Hopperton, ...
The Journal of Nutritional Biochemistry 46, 143-150, 2017
202017
Natural abundance carbon isotopic analysis indicates the equal contribution of local synthesis and plasma uptake to palmitate levels in the mouse brain
RJS Lacombe, V Giuliano, R Chouinard‐Watkins, RP Bazinet
Lipids 53 (5), 481-490, 2018
182018
Natural abundance carbon isotope ratio analysis and its application in the study of diet and metabolism
RJS Lacombe, RP Bazinet
Nutrition reviews 79 (8), 869-888, 2021
172021
Turnover of brain DHA in mice is accurately determined by tracer-free natural abundance carbon isotope ratio analysis
RJS Lacombe, CC Lee, RP Bazinet
Journal of lipid research 61 (1), 116-126, 2020
172020
Two weeks of docosahexaenoic acid (DHA) supplementation increases synthesis-secretion kinetics of n-3 polyunsaturated fatty acids compared to 8 weeks of DHA supplementation
AH Metherel, RJS Lacombe, JJA Henao, D Morin-Rivron, AP Kitson, ...
The Journal of nutritional biochemistry 60, 24-34, 2018
152018
Applying stable carbon isotopic analysis at the natural abundance level to determine the origin of docosahexaenoic acid in the brain of the fat-1 mouse
V Giuliano, RJS Lacombe, KE Hopperton, RP Bazinet
Biochimica et Biophysica Acta (BBA)-Molecular and Cell Biology of Lipids …, 2018
122018
A scoping review of clinical studies in infants fed formulas containing palm oil or palm olein and Sn-2 palmitate
ME Smith, G Cisbani, RJS Lacombe, RP Bazinet
The Journal of Nutrition 151 (10), 2997-3035, 2021
92021
Toward quantitative sequencing of deuteration of unsaturated hydrocarbon chains in fatty acids
DH Wang, HG Park, Z Wang, RJS Lacombe, VV Shmanai, AV Bekish, ...
Analytical Chemistry 93 (23), 8238-8247, 2021
92021
Plasma unesterified eicosapentaenoic acid is converted to docosahexaenoic acid (DHA) in the liver and supplies the brain with DHA in the presence or absence of dietary DHA
AH Metherel, K Rezaei, RJS Lacombe, RP Bazinet
Biochimica et Biophysica Acta (BBA)-Molecular and Cell Biology of Lipids …, 2021
82021
Biochemical alterations in white matter tracts of the aging mouse brain revealed by FTIR spectroscopy imaging
KL Furber, RJS Lacombe, S Caine, MP Thangaraj, S Read, ...
Neurochemical Research, 1-16, 2022
72022
Maternal dietary n-6 polyunsaturated fatty acid deprivation does not exacerbate post-weaning reductions in arachidonic acid and its mediators in the mouse hippocampus
SM Alashmali, AP Kitson, L Lin, RJS Lacombe, RP Bazinet
Nutritional Neuroscience 22 (4), 223-234, 2019
72019
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