Follow
Patricia Sime
Patricia Sime
Unknown affiliation
Verified email at vcu.edu
Title
Cited by
Cited by
Year
Adenovector-mediated gene transfer of active transforming growth factor-beta1 induces prolonged severe fibrosis in rat lung.
PJ Sime, Z Xing, FL Graham, KG Csaky, J Gauldie
The Journal of clinical investigation 100 (4), 768-776, 1997
12731997
Fibrosis of the lung and other tissues: new concepts in pathogenesis and treatment
PJ Sime, KMA O'Reilly
Clinical immunology 99 (3), 308-319, 2001
4782001
PPARγ agonists inhibit TGF-β induced pulmonary myofibroblast differentiation and collagen production: implications for therapy of lung fibrosis
HA Burgess, LE Daugherty, TH Thatcher, HF Lakatos, DM Ray, ...
American Journal of Physiology-Lung Cellular and Molecular Physiology 288 (6 …, 2005
4112005
Transfer of tumor necrosis factor-α to rat lung induces severe pulmonary inflammation and patchy interstitial fibrogenesis with induction of transforming growth factor-β1 and …
PJ Sime, RA Marr, D Gauldie, Z Xing, BR Hewlett, FL Graham, J Gauldie
The American journal of pathology 153 (3), 825-832, 1998
3831998
Overexpression of active TGF-beta-1 in the murine knee joint: evidence for synovial-layer-dependent chondro-osteophyte formation
AC Bakker, FAJ Van De Loo, HM Van Beuningen, P Sime, P Van Lent, ...
Osteoarthritis and cartilage 9 (2), 128-136, 2001
3622001
Proteoglycans decorin and biglycan differentially modulate TGF-β-mediated fibrotic responses in the lung
M Kolb, PJ Margetts, PJ Sime, J Gauldie
American Journal of Physiology-Lung Cellular and Molecular Physiology 280 (6 …, 2001
3372001
Lactic acid is elevated in idiopathic pulmonary fibrosis and induces myofibroblast differentiation via pH-dependent activation of transforming growth factor-β
RM Kottmann, AA Kulkarni, KA Smolnycki, E Lyda, T Dahanayake, ...
American journal of respiratory and critical care medicine 186 (8), 740-751, 2012
3172012
Asbestos-related lung disease
KMA O'REILLY, AM Mclaughlin, WS Beckett, PJ Sime
American family physician 75 (5), 683-688, 2007
3172007
An official American Thoracic Society workshop report: use of animal models for the preclinical assessment of potential therapies for pulmonary fibrosis
RG Jenkins, BB Moore, RC Chambers, O Eickelberg, M Königshoff, ...
American journal of respiratory cell and molecular biology 56 (5), 667-679, 2017
2892017
Transient transgene expression of decorin in the lung reduces the fibrotic response to bleomycin
M Kolb, PJ Margetts, T Galt, PJ Sime, Z Xing, M Schmidt, J Gauldie
American journal of respiratory and critical care medicine 163 (3), 770-777, 2001
2782001
Cigarette smoke induces cyclooxygenase-2 and microsomal prostaglandin E2 synthase in human lung fibroblasts: implications for lung inflammation and cancer
CA Martey, SJ Pollock, CK Turner, KMA O'Reilly, CJ Baglole, RP Phipps, ...
American Journal of Physiology-Lung Cellular and Molecular Physiology 287 (5 …, 2004
2772004
TGF-β, Smad3 and the process of progressive fibrosis
J Gauldie, P Bonniaud, P Sime, K Ask, M Kolb
Biochemical Society Transactions 35 (4), 661-664, 2007
2492007
Future directions in idiopathic pulmonary fibrosis research. An NHLBI workshop report
TS Blackwell, AM Tager, Z Borok, BB Moore, DA Schwartz, KJ Anstrom, ...
American journal of respiratory and critical care medicine 189 (2), 214-222, 2014
2452014
PPAR-γ ligands repress TGFβ-induced myofibroblast differentiation by targeting the PI3K/Akt pathway: implications for therapy of fibrosis
AA Kulkarni, TH Thatcher, KC Olsen, SB Maggirwar, RP Phipps, PJ Sime
PloS one 6 (1), e15909, 2011
2422011
PPARγ and the innate immune system mediate the resolution of inflammation
A Croasdell, PF Duffney, N Kim, SH Lacy, PJ Sime, RP Phipps
PPAR research 2015, 2015
2262015
Inflammation resolution: a dual-pronged approach to averting cytokine storms in COVID-19?
D Panigrahy, MM Gilligan, S Huang, A Gartung, I Cortés-Puch, PJ Sime, ...
Cancer and metastasis reviews 39, 337-340, 2020
2252020
A novel anti-inflammatory and pro-resolving role for resolvin D1 in acute cigarette smoke-induced lung inflammation
HM Hsiao, RE Sapinoro, TH Thatcher, A Croasdell, EP Levy, RA Fulton, ...
PloS one 8 (3), e58258, 2013
2182013
Aryl hydrocarbon receptor-deficient mice develop heightened inflammatory responses to cigarette smoke and endotoxin associated with rapid loss of the nuclear factor-κB …
TH Thatcher, SB Maggirwar, CJ Baglole, HF Lakatos, TA Gasiewicz, ...
The American journal of pathology 170 (3), 855-864, 2007
2122007
Oropharyngeal aspiration of a silica suspension produces a superior model of silicosis in the mouse when compared to intratracheal instillation
HF Lakatos, HA Burgess, TH Thatcher, MR Redonnet, E Hernady, ...
Experimental lung research 32 (5), 181-199, 2006
2052006
Differences in the Fibrogenic Response after Transfer of Active Transforming Growth Factor-β1 Gene to Lungs of “Fibrosis-prone” and “Fibrosis-resistant” Mouse …
M Kolb, P Bonniaud, T Galt, PJ Sime, MM Kelly, PJ Margetts, J Gauldie
American journal of respiratory cell and molecular biology 27 (2), 141-150, 2002
2012002
The system can't perform the operation now. Try again later.
Articles 1–20