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Santhana Devaraj
Santhana Devaraj
Postdoctoral Research Associate, Houston Methodist Research Institutue
Verified email at houstonmethodist.org - Homepage
Title
Cited by
Cited by
Year
Regulation of IRF-3-dependent innate immunity by the papain-like protease domain of the severe acute respiratory syndrome coronavirus
SG Devaraj, N Wang, Z Chen, Z Chen, M Tseng, N Barretto, R Lin, ...
Journal of Biological Chemistry 282 (44), 32208-32221, 2007
4362007
Highly effective combination of LSD1 (KDM1A) antagonist and pan-histone deacetylase inhibitor against human AML cells
W Fiskus, S Sharma, B Shah, BP Portier, SGT Devaraj, K Liu, SP Iyer, ...
Leukemia 28 (11), 2155-2164, 2014
2922014
Toll-like receptor 3 mediates establishment of an antiviral state against hepatitis C virus in hepatoma cells
N Wang, Y Liang, S Devaraj, J Wang, SM Lemon, K Li
Journal of virology 83 (19), 9824-9834, 2009
2552009
Highly active combination of BRD4 antagonist and histone deacetylase inhibitor against human acute myelogenous leukemia cells
W Fiskus, S Sharma, J Qi, JA Valenta, LJ Schaub, B Shah, K Peth, ...
Molecular cancer therapeutics 13 (5), 1142-1154, 2014
2032014
Histone deacetylase inhibitor treatment induces ‘BRCAness’ and synergistic lethality with PARP inhibitor and cisplatin against human triple negative breast cancer cells
K Ha, W Fiskus, DS Choi, S Bhaskara, L Cerchietti, SGT Devaraj, B Shah, ...
Oncotarget 5 (14), 5637, 2014
1572014
Ubiquitination and proteasomal degradation of interferon regulatory factor-3 induced by Npro from a cytopathic bovine viral diarrhea virus
Z Chen, R Rijnbrand, RK Jangra, SG Devaraj, L Qu, Y Ma, SM Lemon, ...
Virology 366 (2), 277-292, 2007
1522007
BET protein antagonist JQ1 is synergistically lethal with FLT3 tyrosine kinase inhibitor (TKI) and overcomes resistance to FLT3-TKI in AML cells expressing FLT-ITD
W Fiskus, S Sharma, J Qi, B Shah, SGT Devaraj, C Leveque, BP Portier, ...
Molecular cancer therapeutics 13 (10), 2315-2327, 2014
1502014
Synergistic activity of BET protein antagonist-based combinations in mantle cell lymphoma cells sensitive or resistant to ibrutinib
B Sun, B Shah, W Fiskus, J Qi, K Rajapakshe, C Coarfa, L Li, ...
Blood, The Journal of the American Society of Hematology 126 (13), 1565-1574, 2015
1182015
Pre-clinical efficacy of combined therapy with novel β-catenin antagonist BC2059 and histone deacetylase inhibitor against AML cells
W Fiskus, S Sharma, S Saha, B Shah, SGT Devaraj, B Sun, S Horrigan, ...
Leukemia 29 (6), 1267-1278, 2015
1152015
A molecular switch in the capsid protein controls the particle polymorphism in an icosahedral virus
GL Lokesh, TDS Gowri, PS Satheshkumar, MRN Murthy, HS Savithri
Virology 292 (2), 211-223, 2002
712002
Complete genomic sequence of Pepper vein banding virus (PVBV): a distinct member of the genus Potyvirus
R Anindya, J Joseph, TDS Gowri, HS Savithri
Archives of virology 149, 625-632, 2004
482004
HEXIM1 induction is mechanistically involved in mediating anti-AML activity of BET protein bromodomain antagonist
SGT Devaraj, W Fiskus, B Shah, J Qi, B Sun, SP Iyer, S Sharma, ...
Leukemia 30 (2), 504-508, 2016
402016
Erratum: Highly effective combination of LSD1 (KDM1A) antagonist and pan-histone deacetylase inhibitor against human AML cells
W Fiskus, S Sharma, B Shah, BP Portier, SGT Devaraj, K Liu, SP Iyer, ...
Leukemia 31 (7), 1658-1658, 2017
192017
DNA aptamer against anti-programmed cell death-1 (anti-PD1-apt) induces robust anti-leukemic activity in vitro and in vivo humanized NSG mice with myeloid leukemia xenografts
SGT Devaraj, LGL Rao, Y Zu, J Chang, SP Iyer
Blood 130, 1373, 2017
52017
Peters. CJ Tseng, CK, Baker, SC, Li, K. Regulation of IRF-3-dependent innate immunity by the papain-like protease domain of the severe acute respiratory syndrome coronavirus
SG Devaraj, N Wang, Z Chen, Z Chen
J Biol Chem 282, 32208-32221, 2007
42007
Mechanistic role of HEXIM1 induction in BRD4-antagonist mediated growth inhibition, differentiation and in vivo lethal activity against human aml blast progenitor cells
SGT Devaraj, W Fiskus, B Shah, S Sharma, J Qi, B Sun, S Saha, SP Iyer, ...
Blood 124 (21), 3534, 2014
22014
Superior Pre-Clinical Activity of BET (Bromodomain and Extra terminal) Protein Antagonist Combined with Ibrutinib, Panobinostat or Carfilzomib Against Human Mantle Cell …
B Sun, W Fiskus, B Shah, J Qi, SGT Devaraj, SP Iyer, S Sharma, ...
Blood 124 (21), 918, 2014
12014
HEXIM1 induction exerts a mechanistic role and is a biomarker of lethal activity of BRD4 antagonist against human AML cells
SGT Devaraj, W Fiskus, S Sharma, J Qi, B Shah, LJ Schaub, M Rodriguez, ...
Cancer Research 74 (19_Supplement), 3686-3686, 2014
12014
BRD4 antagonist-based therapy exerts lethal activity against FLT3 mutation expressing AML cells resistant to FLT3 tyrosine kinase inhibitors
M Rodriguez, W Fiskus, S Sharma, J Qi, LJ Schaub, B Shah, SGT Devaraj, ...
Cancer Research 74 (19_Supplement), 1721-1721, 2014
12014
Combined Therapy With BRD4 Antagonist and JAK Inhibitor Is Synergistically Lethal Against Human Myeloproliferative Neoplasm (MPN) Cells
JA Valenta, W Fiskus, T Manshouri, S Sharma, J Qi, LJ Schaub, B Shah, ...
Blood 122 (21), 2842, 2013
12013
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