Mandi E Schmidt
Mandi E Schmidt
Centre for Molecular Medicine and Therapeutics
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Hip14l-deficient mice develop neuropathological and behavioural features of Huntington disease
LM Sutton, SS Sanders, SL Butland, RR Singaraja, S Franciosi, ...
Human molecular genetics 22 (3), 452-465, 2013
The palmitoyl acyltransferase HIP14 shares a high proportion of interactors with huntingtin: implications for a role in the pathogenesis of Huntington's disease
SL Butland, SS Sanders, ME Schmidt, SP Riechers, DTS Lin, DDO Martin, ...
Human molecular genetics 23 (15), 4142-4160, 2014
Preventing mutant huntingtin proteolysis and intermittent fasting promote autophagy in models of Huntington disease
DE Ehrnhoefer, DDO Martin, ME Schmidt, X Qiu, S Ladha, NS Caron, ...
Acta neuropathologica communications 6 (1), 1-16, 2018
Western Database of Lipid Variants (WDLV): a catalogue of genetic variants in monogenic dyslipidemias
J Fu, S Kwok, L Sinai, O Abdel-Razek, J Babula, D Chen, E Farago, ...
Canadian Journal of Cardiology 29 (8), 934-939, 2013
Identification of a novel caspase cleavage site in huntingtin that regulates mutant huntingtin clearance
DDO Martin, ME Schmidt, YT Nguyen, N Lazic, MR Hayden
The FASEB Journal 33 (3), 3190-3197, 2019
Altering cortical input unmasks synaptic phenotypes in the YAC128 cortico-striatal co-culture model of Huntington disease
ME Schmidt, C Buren, JP Mackay, D Cheung, L Dal Cengio, LA Raymond, ...
BMC Biology 16 (1), 58, 2018
The Interaction of Aging and Cellular Stress Contributes to Pathogenesis in Mouse and Human Huntington Disease Neurons
E Machiela, R Jeloka, NS Caron, S Mehta, ME Schmidt, HJE Baddeley, ...
Frontiers in Aging Neuroscience 12, 288, 2020
DAPK1 promotes extrasynaptic GluN2B phosphorylation and striatal spine instability in the YAC128 mouse model of Huntington disease
ME Schmidt, NS Caron, AE Aly, FL Lemariť, L Dal Cengio, Y Ko, N Lazic, ...
Frontiers in Cellular Neuroscience 14, 348, 2020
Axonal ER Ca2+ Release Enhances Miniature, but Reduces Activity-Dependent Glutamate Release in a Huntington Disease Model
JP Mackay, AI Smith-Dijak, ET Koch, P Zhang, E Fung, WB Nassrallah, ...
bioRxiv, 2020
Understanding and modulating synaptic dysfunction in Huntington disease
ME Schmidt
University of British Columbia, 2019
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