Towards a comprehensive characterisation of the human internal chemical exposome: Challenges and perspectives A David, J Chaker, EJ Price, V Bessonneau, AJ Chetwynd, CM Vitale, ... Environment International 156, 106630, 2021 | 44 | 2021 |
CGRP-dependent signalling pathways involved in mouse models of GTN-cilostazol-and levcromakalim-induced migraine SL Christensen, RH Rasmussen, C Ernstsen, S La Cour, A David, ... Cephalalgia 41 (14), 1413-1426, 2021 | 31 | 2021 |
From metabolomics to HRMS-based exposomics: adapting peak picking and developing scoring for MS1 suspect screening J Chaker, E Gilles, T Léger, B Jégou, A David Analytical Chemistry 93 (3), 1792-1800, 2020 | 26 | 2020 |
Acetaminophen metabolism revisited using non-targeted analyses: Implications for human biomonitoring A David, J Chaker, T Léger, R Al-Salhi, MD Dalgaard, B Styrishave, ... Environment International 149, 106388, 2021 | 22 | 2021 |
Comprehensive evaluation of blood plasma and serum sample preparations for HRMS-based chemical exposomics: overlaps and specificities J Chaker, DM Kristensen, TI Halldorsson, SF Olsen, C Monfort, C Chevrier, ... Analytical Chemistry 94 (2), 866-874, 2022 | 9 | 2022 |
Human sperm cells can form paracetamol metabolite AM404 that directly interferes with sperm calcium signalling and function through a CatSper-dependent mechanism A Rehfeld, H Frederiksen, RH Rasmussen, A David, J Chaker, BS Nielsen, ... Human Reproduction 37 (5), 922-935, 2022 | 8 | 2022 |
Improving Exposure Assessment Using Non-Targeted and Suspect Screening: The ISO/IEC 17025: 2017 Quality Standard as a Guideline J Monteiro Bastos da Silva, J Chaker, A Martail, J Costa Moreira, A David, ... Journal of Xenobiotics 11 (1), 1-15, 2021 | 6 | 2021 |
Exposome chimique et approches «non ciblées»-Un changement de paradigme pour évaluer l’exposition des populations aux contaminants chimiques A David, J Chaker, L Multigner, V Bessonneau médecine/sciences 37 (10), 895-901, 2021 | 2 | 2021 |
Scannotation: A Suspect Screening Tool for the Rapid Pre-Annotation of the Human LC-HRMS-Based Chemical Exposome J Chaker, E Gilles, C Monfort, C Chevrier, S Lennon, A David Environmental Science & Technology 57 (48), 19253-19262, 2023 | 1 | 2023 |
Chemical exposome and non-targeted approaches A David, J Chaker, L Multigner, V Bessonneau Medecine Sciences: M/S 37 (10), 895-901, 2021 | 1 | 2021 |
Assessing the contribution of the chemical exposome to neurodegenerative disease S Lefèvre-Arbogast, J Chaker, F Mercier, R Barouki, X Coumoul, ... Nature Neuroscience, 1-10, 2024 | | 2024 |
Innovative analytical methodologies for characterizing chemical exposure with a view to next-generation risk assessment Ž Tkalec, JP Antignac, N Bandow, FM Béen, L Belova, J Bessems, ... Environment international 186, 108585, 2024 | | 2024 |
Harmonized quality assurance/quality control provisions to assess completeness and robustness of MS1 data preprocessing for LC-HRMS-based suspect screening and non-targeted … S Lennon, J Chaker, EJ Price, J Hollender, C Huber, T Schulze, L Ahrens, ... TrAC Trends in Analytical Chemistry, 117674, 2024 | | 2024 |
High-resolution mass spectrometry identifies delayed biomarkers for improved precision in acetaminophen/paracetamol human biomonitoring E Gorrochategui, M Le Vee, H Selmi, A Gérard, J Chaker, AM Krais, ... Environment International 181, 108299, 2023 | | 2023 |
What is in the fish? Collaborative trial in suspect and non-target screening of organic micropollutants using LC-and GC-HRMS W Dürig, S Lindblad, O Golovko, G Gkotsis, R Aalizadeh, MC Nika, ... Environment international 181, 108288, 2023 | | 2023 |
Paracetamol/acetaminophen hepatotoxicity: new markers for monitoring the elimination of the reactive N-Acetyl-p-benzoquinone imine E Gorrochategui, ML Vee, H Selmi, A Gérard, J Chaker, AM Krais, C Lindh, ... bioRxiv, 2023.04. 28.538718, 2023 | | 2023 |
Développements analytiques pour la caractérisation non-ciblée et par profilage de suspects de l’exposome chimique dans le plasma et le sérum humain par LC-ESI-HRMS … J Chaker Rennes, École des hautes études en santé publique, 2022 | | 2022 |
Methodological developments for the non-targeted characterization of the human internal chemical exposome in epidemiological studies: optimizing and implementing a high … J Chaker École des Hautes Études en Santé Publique [EHESP], 2022 | | 2022 |
Optimizing a suspect screening annotation workflow for large-scale application in human cohorts J Chaker, T Léger, E Gilles, B Jégou, DM Kristensen, A David SETAC Europe 30th Annual Meeting - SciCon, 2020 | | 2020 |