Genomic and transcriptomic landscape of triple-negative breast cancers: subtypes and treatment strategies YZ Jiang, D Ma, C Suo, J Shi, M Xue, X Hu, Y Xiao, KD Yu, YR Liu, Y Yu, ... Cancer cell 35 (3), 428-440. e5, 2019 | 829 | 2019 |
Intrinsic gene expression profiles of gliomas are a better predictor of survival than histology LAM Gravendeel, MCM Kouwenhoven, O Gevaert, JJ de Rooi, AP Stubbs, ... Cancer research 69 (23), 9065-9072, 2009 | 712 | 2009 |
Glutamine sensitivity analysis identifies the xCT antiporter as a common triple-negative breast tumor therapeutic target LA Timmerman, T Holton, M Yuneva, RJ Louie, M Padrķ, A Daemen, ... Cancer cell 24 (4), 450-465, 2013 | 601 | 2013 |
HE4 and CA125 as a diagnostic test in ovarian cancer: prospective validation of the Risk of Ovarian Malignancy Algorithm T Van Gorp, I Cadron, E Despierre, A Daemen, K Leunen, F Amant, ... British journal of cancer 104 (5), 863-870, 2011 | 450 | 2011 |
Metabolite profiling stratifies pancreatic ductal adenocarcinomas into subtypes with distinct sensitivities to metabolic inhibitors A Daemen, D Peterson, N Sahu, R McCord, X Du, B Liu, K Kowanetz, ... Proceedings of the National Academy of Sciences 112 (32), E4410-E4417, 2015 | 377 | 2015 |
Modeling precision treatment of breast cancer A Daemen, OL Griffith, LM Heiser, NJ Wang, OM Enache, Z Sanborn, ... Genome biology 14, 1-14, 2013 | 345 | 2013 |
Metabolic plasticity underpins innate and acquired resistance to LDHA inhibition A Boudreau, HE Purkey, A Hitz, K Robarge, D Peterson, S Labadie, ... Nature chemical biology 12 (10), 779-786, 2016 | 243 | 2016 |
Single-cell dissection of cellular components and interactions shaping the tumor immune phenotypes in ovarian cancer M Hornburg, M Desbois, S Lu, Y Guan, AA Lo, S Kaufman, A Elrod, ... Cancer cell 39 (7), 928-944. e6, 2021 | 233 | 2021 |
mTORC1-dependent metabolic reprogramming underlies escape from glycolysis addiction in cancer cells RV Pusapati, A Daemen, C Wilson, W Sandoval, M Gao, B Haley, ... Cancer cell 29 (4), 548-562, 2016 | 214 | 2016 |
Recurrent loss of NFE2L2 exon 2 is a mechanism for Nrf2 pathway activation in human cancers LD Goldstein, J Lee, F Gnad, C Klijn, A Schaub, J Reeder, A Daemen, ... Cell reports 16 (10), 2605-2617, 2016 | 198 | 2016 |
Therapeutic ligands antagonize estrogen receptor function by impairing its mobility J Guan, W Zhou, M Hafner, RA Blake, C Chalouni, IP Chen, T De Bruyn, ... Cell 178 (4), 949-963. e18, 2019 | 185 | 2019 |
Limitations of current definitions of miscarriage using mean gestational sac diameter and crown–rump length measurements: a multicenter observational study Y Abdallah, A Daemen, E Kirk, A Pexsters, O Naji, C Stalder, D Gould, ... Ultrasound in obstetrics & gynecology 38 (5), 497-502, 2011 | 164 | 2011 |
Integrated digital pathology and transcriptome analysis identifies molecular mediators of T-cell exclusion in ovarian cancer M Desbois, AR Udyavar, L Ryner, C Kozlowski, Y Guan, M Dürrbaum, ... Nature communications 11 (1), 5583, 2020 | 152 | 2020 |
Metabolic and transcriptional profiling reveals pyruvate dehydrogenase kinase 4 as a mediator of epithelial-mesenchymal transition and drug resistance in tumor cells Y Sun, A Daemen, G Hatzivassiliou, D Arnott, C Wilson, G Zhuang, M Gao, ... Cancer & metabolism 2, 1-14, 2014 | 149 | 2014 |
L2-norm multiple kernel learning and its application to biomedical data fusion S Yu, T Falck, A Daemen, LC Tranchevent, JAK Suykens, B De Moor, ... BMC bioinformatics 11, 1-24, 2010 | 148 | 2010 |
Targetable mechanisms driving immunoevasion of persistent senescent cells link chemotherapy-resistant cancer to aging DP Muņoz, SM Yannone, A Daemen, Y Sun, F Vakar-Lopez, M Kawahara, ... JCI insight 4 (14), 2019 | 147 | 2019 |
Molecular response to cetuximab and efficacy of preoperative cetuximab-based chemoradiation in rectal cancer A Debucquoy, K Haustermans, A Daemen, S Aydin, L Libbrecht, ... Journal of Clinical Oncology 27 (17), 2751-2757, 2009 | 138 | 2009 |
Germline genetic polymorphisms influence tumor gene expression and immune cell infiltration YW Lim, H Chen-Harris, O Mayba, S Lianoglou, A Wuster, T Bhangale, ... Proceedings of the National Academy of Sciences 115 (50), E11701-E11710, 2018 | 125 | 2018 |
Hominoid-specific enzyme GLUD2 promotes growth of IDH1R132H glioma R Chen, MC Nishimura, S Kharbanda, F Peale, Y Deng, A Daemen, ... Proceedings of the National Academy of Sciences 111 (39), 14217-14222, 2014 | 125 | 2014 |
Occurrence and outcome of residual trophoblastic tissue: a prospective study T Van den Bosch, A Daemen, D Van Schoubroeck, N Pochet, B De Moor, ... Journal of Ultrasound in Medicine 27 (3), 357-361, 2008 | 125 | 2008 |