|Purification and molecular cloning of a secreted, Frizzled-related antagonist of Wnt action|
PW Finch, X He, MJ Kelley, A Üren, RP Schaudies, NC Popescu, ...
Proceedings of the National Academy of Sciences 94 (13), 6770-6775, 1997
|Secreted frizzled-related protein-1 binds directly to Wingless and is a biphasic modulator of Wnt signaling|
A Uren, F Reichsman, V Anest, WG Taylor, K Muraiso, DP Bottaro, ...
Journal of Biological Chemistry 275 (6), 4374-4382, 2000
|A small molecule blocking oncogenic protein EWS-FLI1 interaction with RNA helicase A inhibits growth of Ewing's sarcoma|
HV Erkizan, Y Kong, M Merchant, S Schlottmann, JS Barber-Rotenberg, ...
Nature medicine 15 (7), 750-756, 2009
|Arsenic trioxide inhibits human cancer cell growth and tumor development in mice by blocking Hedgehog/GLI pathway|
EM Beauchamp, L Ringer, G Bulut, KP Sajwan, MD Hall, YC Lee, ...
The Journal of clinical investigation 121 (1), 148-160, 2011
|Activation of the canonical Wnt pathway during genital keratinocyte transformation: a model for cervical cancer progression|
A Üren, S Fallen, H Yuan, A Usubütün, T Küçükali, R Schlegel, ...
Cancer research 65 (14), 6199-6206, 2005
|GLI1 is a direct transcriptional target of EWS-FLI1 oncoprotein|
E Beauchamp, G Bulut, O Abaan, K Chen, A Merchant, W Matsui, Y Endo, ...
Journal of Biological Chemistry 284 (14), 9074-9082, 2009
|Predicting new indications for approved drugs using a proteochemometric method|
S Dakshanamurthy, NT Issa, S Assefnia, A Seshasayee, OJ Peters, ...
Journal of medicinal chemistry 55 (15), 6832-6848, 2012
|Oncoprotein EWS-FLI1 activity is enhanced by RNA helicase A|
JA Toretsky, V Erkizan, A Levenson, OD Abaan, JD Parvin, TP Cripe, ...
Cancer research 66 (11), 5574-5581, 2006
|Small molecule inhibitors of ezrin inhibit the invasive phenotype of osteosarcoma cells|
G Bulut, SH Hong, K Chen, EM Beauchamp, S Rahim, GW Kosturko, ...
Oncogene 31 (3), 269-281, 2012
|Toward a Drug Development Path That Targets Metastatic Progression in OsteosarcomaDrug Development for Metastatic Progression in Osteosarcoma|
C Khanna, TM Fan, R Gorlick, LJ Helman, ES Kleinerman, PC Adamson, ...
Clinical Cancer Research 20 (16), 4200-4209, 2014
|Secreted Frizzled-related proteins can regulate metanephric development|
K Yoshino, JS Rubin, KG Higinbotham, A Üren, V Anest, SY Plisov, ...
Mechanisms of development 102 (1-2), 45-55, 2001
|Preparation of F-18 labeled annexin V: a potential PET radiopharmaceutical for imaging cell death|
J Toretsky, A Levenson, IN Weinberg, JF Tait, A Üren, RC Mease
Nuclear medicine and biology 31 (6), 747-752, 2004
|Oncogenic fusion protein EWS-FLI1 is a network hub that regulates alternative splicing|
SP Selvanathan, GT Graham, HV Erkizan, U Dirksen, TG Natarajan, ...
Proceedings of the National Academy of Sciences 112 (11), E1307-E1316, 2015
|Wnt signaling promotes proliferation and stemness regulation of spermatogonial stem/progenitor cells|
N Golestaneh, E Beauchamp, S Fallen, M Kokkinaki, A Uren, M Dym
Reproduction 138 (1), 151, 2009
|Wnt-3a-dependent Cell Motility Involves RhoA Activation and Is Specifically Regulated by Dishevelled-2*[boxs]|
Y Endo, V Wolf, K Muraiso, K Kamijo, L Soon, A Uren, ...
Journal of Biological Chemistry 280 (1), 777-786, 2005
|Keratinocyte growth factor facilitates alloengraftment and ameliorates graft-versus-host disease in mice by a mechanism independent of repair of conditioning-induced tissue injury|
A Panoskaltsis-Mortari, PA Taylor, JS Rubin, A Uren, LA Welniak, ...
Blood, The Journal of the American Society of Hematology 96 (13), 4350-4356, 2000
|Wnt-3a and Dickkopf-1 stimulate neurite outgrowth in Ewing tumor cells via a Frizzled3-and c-Jun N-terminal kinase-dependent mechanism|
Y Endo, E Beauchamp, D Woods, WG Taylor, JA Toretsky, A Uren, ...
Molecular and cellular biology 28 (7), 2368-2379, 2008
|Disulfide bond assignments of secreted Frizzled-related protein-1 provide insights about Frizzled homology and netrin modules|
JM Chong, A Uren, JS Rubin, DW Speicher
Journal of Biological Chemistry 277 (7), 5134-5144, 2002
|A global benchmark study using affinity-based biosensors|
RL Rich, GA Papalia, PJ Flynn, J Furneisen, J Quinn, JS Klein, ...
Analytical biochemistry 386 (2), 194-216, 2009
|YK-4-279 inhibits ERG and ETV1 mediated prostate cancer cell invasion|
S Rahim, EM Beauchamp, Y Kong, ML Brown, JA Toretsky, A Üren
PloS one 6 (4), e19343, 2011