Metalloprotease SPRTN/DVC1 orchestrates replication-coupled DNA-protein crosslink repair B Vaz, M Popovic, JA Newman, J Fielden, H Aitkenhead, S Halder, ... Molecular cell 64 (4), 704-719, 2016 | 244 | 2016 |
Targeting BRCA1 and BRCA2 deficiencies with G-quadruplex-interacting compounds J Zimmer, EMC Tacconi, C Folio, S Badie, M Porru, K Klare, M Tumiati, ... Molecular cell 61 (3), 449-460, 2016 | 230 | 2016 |
Mutations in SPRTN cause early onset hepatocellular carcinoma, genomic instability and progeroid features D Lessel, B Vaz, S Halder, PJ Lockhart, I Marinovic-Terzic, ... Nature genetics 46 (11), 1239-1244, 2014 | 215 | 2014 |
Colonic microbiota alters host susceptibility to infectious colitis by modulating inflammation, redox status, and ion transporter gene expression S Ghosh, C Dai, K Brown, E Rajendiran, S Makarenko, J Baker, C Ma, ... American Journal of Physiology-Gastrointestinal and Liver Physiology 301 (1 …, 2011 | 163 | 2011 |
Role of p97/VCP (Cdc48) in genome stability B Vaz, S Halder, K Ramadan Frontiers in genetics 4, 60, 2013 | 107 | 2013 |
Determinants of prakriti, the human constitution types of Indian traditional medicine and its correlation with contemporary science H Rotti, R Raval, S Anchan, R Bellampalli, S Bhale, R Bharadwaj, ... Journal of Ayurveda and integrative medicine 5 (3), 167, 2014 | 86 | 2014 |
A ruthenium polypyridyl intercalator stalls DNA replication forks, radiosensitizes human cancer cells and is enhanced by Chk1 inhibition MR Gill, SN Harun, S Halder, RA Boghozian, K Ramadan, H Ahmad, ... Scientific reports 6 (1), 31973, 2016 | 56 | 2016 |
Strategic role of the ubiquitin-dependent segregase p97 (VCP or Cdc48) in DNA replication K Ramadan, S Halder, K Wiseman, B Vaz Chromosoma 126 (1), 17-32, 2017 | 55 | 2017 |
Short term exercise induces PGC-1α, ameliorates inflammation and increases mitochondrial membrane proteins but fails to increase respiratory enzymes in aging diabetic hearts A Botta, I Laher, J Beam, D DeCoffe, K Brown, S Halder, A Devlin, ... PLoS One 8 (8), e70248, 2013 | 55 | 2013 |
SPRTN protease and checkpoint kinase 1 cross-activation loop safeguards DNA replication S Halder, I Torrecilla, MD Burkhalter, M Popović, J Fielden, B Vaz, ... Nature communications 10 (1), 3142, 2019 | 53 | 2019 |
Chromatin-associated degradation is defined by UBXN-3/FAF1 to safeguard DNA replication fork progression A Franz, PA Pirson, D Pilger, S Halder, D Achuthankutty, H Kashkar, ... Nature communications 7 (1), 10612, 2016 | 46 | 2016 |
A three-in-one-bullet for oesophageal cancer: replication fork collapse, spindle attachment failure and enhanced radiosensitivity generated by a ruthenium (II) metallo-intercalator MR Gill, PJ Jarman, S Halder, MG Walker, HK Saeed, JA Thomas, ... Chemical Science 9 (4), 841-849, 2018 | 36 | 2018 |
Double-stranded DNA binding function of RAD51 in DNA protection and its regulation by BRCA2 S Halder, A Sanchez, L Ranjha, G Reginato, I Ceppi, A Acharya, R Anand, ... Molecular Cell 82 (19), 3553-3565. e5, 2022 | 23 | 2022 |
Strand annealing and motor driven activities of SMARCAL1 and ZRANB3 are stimulated by RAD51 and the paralog complex S Halder, L Ranjha, A Taglialatela, A Ciccia, P Cejka Nucleic Acids Research 50 (14), 8008-8022, 2022 | 18 | 2022 |
WRN helicase and mismatch repair complexes independently and synergistically disrupt cruciform DNA structures V Mengoli, I Ceppi, A Sanchez, E Cannavo, S Halder, S Scaglione, ... The EMBO Journal 42 (3), e111998, 2023 | 11 | 2023 |
Mechanism of BRCA1-BARD1 function in DNA end resection and DNA protection P Cejka, I Ceppi, MRD Stritto, S Braunshier, M Mutze, G Reginato, ... | | 2024 |
The role of p97 cofactors SPRTN and FAF1 in DNA replication S Halder University of Oxford, 2016 | | 2016 |