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Calvin Roskelley
Calvin Roskelley
University of British Columbia
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A biomarker that identifies senescent human cells in culture and in aging skin in vivo.
GP Dimri, X Lee, G Basile, M Acosta, G Scott, C Roskelley, EE Medrano, ...
Proceedings of the National Academy of Sciences 92 (20), 9363-9367, 1995
85261995
Expression of the ETV6-NTRK3 gene fusion as a primary event in human secretory breast carcinoma
C Tognon, SR Knezevich, D Huntsman, CD Roskelley, N Melnyk, ...
Cancer cell 2 (5), 367-376, 2002
9782002
Targeting tumor hypoxia: suppression of breast tumor growth and metastasis by novel carbonic anhydrase IX inhibitors
Y Lou, PC McDonald, A Oloumi, S Chia, C Ostlund, A Ahmadi, A Kyle, ...
Cancer research 71 (9), 3364-3376, 2011
7652011
Cell adhesion and the integrin-linked kinase regulate the LEF-1 and β-catenin signaling pathways
A Novak, SC Hsu, C Leung-Hagesteijn, G Radeva, J Papkoff, ...
Proceedings of the National Academy of Sciences 95 (8), 4374-4379, 1998
5881998
Extracellular matrix-dependent tissue-specific gene expression in mammary epithelial cells requires both physical and biochemical signal transduction.
CD Roskelley, PY Desprez, MJ Bissell
Proceedings of the National Academy of Sciences 91 (26), 12378-12382, 1994
5801994
A hierarchy of ECM-mediated signalling regulates tissue-specific gene expression
CD Roskelley, A Srebrow, MJ Bissell
Current opinion in cell biology 7 (5), 736-747, 1995
5091995
Laminin mediates tissue-specific gene expression in mammary epithelia.
CH Streuli, C Schmidhauser, N Bailey, P Yurchenco, AP Skubitz, ...
The Journal of cell biology 129 (3), 591-603, 1995
4931995
The integrin-linked kinase (ILK) suppresses anoikis
S Attwell, C Roskelley, S Dedhar
Oncogene 19 (33), 3811-3815, 2000
3422000
E-cadherin induces mesenchymal-to-epithelial transition in human ovarian surface epithelium
N Auersperg, J Pan, BD Grove, T Peterson, J Fisher, S Maines-Bandiera, ...
Proceedings of the National Academy of Sciences 96 (11), 6249-6254, 1999
3351999
The integrin linked kinase (ILK) induces an invasive phenotype via AP-1 transcription factor-dependent upregulation of matrix metalloproteinase 9 (MMP-9)
AA Troussard, P Costello, TN Yoganathan, S Kumagai, CD Roskelley, ...
Oncogene 19 (48), 5444-5452, 2000
2522000
The dominance of the microenvironment in breast and ovarian cancer
CD Roskelley, MJ Bissell
Seminars in cancer biology 12 (2), 97-104, 2002
1852002
Overexpression of the anti-adhesin podocalyxin is an independent predictor of breast cancer progression
A Somasiri, JS Nielsen, N Makretsov, ML McCoy, L Prentice, CB Gilks, ...
Cancer research 64 (15), 5068-5073, 2004
1842004
Regulation of BRCA1 expression and its relationship to sporadic breast cancer
CR Mueller, CD Roskelley
Breast Cancer Research 5, 1-8, 2002
1632002
Dynamic reciprocity revisited: a continuous, bidirectional flow of information between cells and the extracellular matrix regulates mammary epithelial cell function
CD Roskelley, MJ Bissell
Biochemistry and cell biology 73 (7-8), 391-397, 1995
1591995
Overexpression of the integrin-linked kinase mesenchymally transforms mammary epithelial cells
A Somasiri, A Howarth, D Goswami, S Dedhar, CD Roskelley
Journal of cell science 114 (6), 1125-1136, 2001
1532001
Integrin-linked kinase activity regulates Rac-and Cdc42-mediated actin cytoskeleton reorganization via α-PIX
NR Filipenko, S Attwell, C Roskelley, S Dedhar
Oncogene 24 (38), 5837-5849, 2005
1452005
Epithelial–mesenchymal transition (EMT) is not sufficient for spontaneous murine breast cancer metastasis
Y Lou, O Preobrazhenska, U auf dem Keller, M Sutcliffe, L Barclay, ...
Developmental Dynamics 237 (10), 2755-2768, 2008
1322008
Collagen-IV and laminin-1 regulate estrogen receptor α expression and function in mouse mammary epithelial cells
V Novaro, CD Roskelley, MJ Bissell
Journal of cell science 116 (14), 2975-2986, 2003
1312003
Division of labor among the α6β4 integrin, β1 integrins, and an E3 laminin receptor to signal morphogenesis and β-casein expression in mammary epithelial cells
J Muschler, A Lochter, CD Roskelley, P Yurchenco, MJ Bissell
Molecular biology of the cell 10 (9), 2817-2828, 1999
1311999
Cofilin-mediated F-actin severing is regulated by the Rap GTPase and controls the cytoskeletal dynamics that drive lymphocyte spreading and BCR microcluster formation
SA Freeman, V Lei, M Dang-Lawson, K Mizuno, CD Roskelley, MR Gold
The Journal of Immunology 187 (11), 5887-5900, 2011
1272011
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