A biomarker that identifies senescent human cells in culture and in aging skin in vivo. GP Dimri, X Lee, G Basile, M Acosta, G Scott, C Roskelley, EE Medrano, ... Proceedings of the National Academy of Sciences 92 (20), 9363-9367, 1995 | 8743 | 1995 |
Expression of the ETV6-NTRK3 gene fusion as a primary event in human secretory breast carcinoma C Tognon, SR Knezevich, D Huntsman, CD Roskelley, N Melnyk, ... Cancer cell 2 (5), 367-376, 2002 | 995 | 2002 |
Targeting tumor hypoxia: suppression of breast tumor growth and metastasis by novel carbonic anhydrase IX inhibitors Y Lou, PC McDonald, A Oloumi, S Chia, C Ostlund, A Ahmadi, A Kyle, ... Cancer research 71 (9), 3364-3376, 2011 | 781 | 2011 |
Cell adhesion and the integrin-linked kinase regulate the LEF-1 and β-catenin signaling pathways A Novak, SC Hsu, C Leung-Hagesteijn, G Radeva, J Papkoff, ... Proceedings of the National Academy of Sciences 95 (8), 4374-4379, 1998 | 588 | 1998 |
Extracellular matrix-dependent tissue-specific gene expression in mammary epithelial cells requires both physical and biochemical signal transduction. CD Roskelley, PY Desprez, MJ Bissell Proceedings of the National Academy of Sciences 91 (26), 12378-12382, 1994 | 578 | 1994 |
A hierarchy of ECM-mediated signalling regulates tissue-specific gene expression CD Roskelley, A Srebrow, MJ Bissell Current opinion in cell biology 7 (5), 736-747, 1995 | 507 | 1995 |
Laminin mediates tissue-specific gene expression in mammary epithelia. CH Streuli, C Schmidhauser, N Bailey, P Yurchenco, AP Skubitz, ... The Journal of cell biology 129 (3), 591-603, 1995 | 490 | 1995 |
The integrin-linked kinase (ILK) suppresses anoikis S Attwell, C Roskelley, S Dedhar Oncogene 19 (33), 3811-3815, 2000 | 344 | 2000 |
E-cadherin induces mesenchymal-to-epithelial transition in human ovarian surface epithelium N Auersperg, J Pan, BD Grove, T Peterson, J Fisher, S Maines-Bandiera, ... Proceedings of the National Academy of Sciences 96 (11), 6249-6254, 1999 | 342 | 1999 |
The integrin linked kinase (ILK) induces an invasive phenotype via AP-1 transcription factor-dependent upregulation of matrix metalloproteinase 9 (MMP-9) AA Troussard, P Costello, TN Yoganathan, S Kumagai, CD Roskelley, ... Oncogene 19 (48), 5444-5452, 2000 | 251 | 2000 |
Overexpression of the anti-adhesin podocalyxin is an independent predictor of breast cancer progression A Somasiri, JS Nielsen, N Makretsov, ML McCoy, L Prentice, CB Gilks, ... Cancer research 64 (15), 5068-5073, 2004 | 185 | 2004 |
The dominance of the microenvironment in breast and ovarian cancer CD Roskelley, MJ Bissell Seminars in cancer biology 12 (2), 97-104, 2002 | 184 | 2002 |
Regulation of BRCA1 expression and its relationship to sporadic breast cancer CR Mueller, CD Roskelley Breast Cancer Research 5, 1-8, 2002 | 167 | 2002 |
Dynamic reciprocity revisited: a continuous, bidirectional flow of information between cells and the extracellular matrix regulates mammary epithelial cell function CD Roskelley, MJ Bissell Biochemistry and cell biology 73 (7-8), 391-397, 1995 | 158 | 1995 |
Overexpression of the integrin-linked kinase mesenchymally transforms mammary epithelial cells A Somasiri, A Howarth, D Goswami, S Dedhar, CD Roskelley Journal of cell science 114 (6), 1125-1136, 2001 | 151 | 2001 |
Integrin-linked kinase activity regulates Rac-and Cdc42-mediated actin cytoskeleton reorganization via α-PIX NR Filipenko, S Attwell, C Roskelley, S Dedhar Oncogene 24 (38), 5837-5849, 2005 | 143 | 2005 |
Epithelial–mesenchymal transition (EMT) is not sufficient for spontaneous murine breast cancer metastasis Y Lou, O Preobrazhenska, U auf dem Keller, M Sutcliffe, L Barclay, ... Developmental Dynamics 237 (10), 2755-2768, 2008 | 137 | 2008 |
Collagen-IV and laminin-1 regulate estrogen receptor α expression and function in mouse mammary epithelial cells V Novaro, CD Roskelley, MJ Bissell Journal of cell science 116 (14), 2975-2986, 2003 | 131 | 2003 |
Cofilin-mediated F-actin severing is regulated by the Rap GTPase and controls the cytoskeletal dynamics that drive lymphocyte spreading and BCR microcluster formation SA Freeman, V Lei, M Dang-Lawson, K Mizuno, CD Roskelley, MR Gold The Journal of Immunology 187 (11), 5887-5900, 2011 | 127 | 2011 |
Division of labor among the α6β4 integrin, β1 integrins, and an E3 laminin receptor to signal morphogenesis and β-casein expression in mammary epithelial cells J Muschler, A Lochter, CD Roskelley, P Yurchenco, MJ Bissell Molecular biology of the cell 10 (9), 2817-2828, 1999 | 127 | 1999 |